KX826 hmoov

KX-826 hmoov yog dab tsi

KX826 hmoov, los yog pyrilamine, yog ib qho androgen receptor antagonist feem ntau pab kho androgenic alopecia (AGA). Randomized, ob-dig muag, kev sim tshuaj placebo yog ua los xyuas kom meej tias cov tshuaj txaus siab rau txhua yam kev nyab xeeb thiab kev ua tau zoo. Vim tias qhov rhiab heev ntawm cov hauv paus plaub hau thiab lawv cov lus teb rau dihydrotestosterone (DHT), AGA nquag tshwm sim. Thaum DHT ib txwm txhawb txoj kev loj hlob ntawm tus cwj pwm cuam tshuam nrog txiv neej pw, DHT ntau dhau hauv cov ntshav tuaj yeem muaj cov kev mob tshwm sim tsis zoo xws li pob txuv, qhov txhab mob, thiab AGA. Finasteride thiab dutasteride, ob txoj kev kho mob nrov niaj hnub no, tau muab cais ua 5ɑ reductase inhibitors. Los ntawm inhibiting 5ɑ reductase, DHT ntau lawm txo, ua rau muaj kev poob qis hauv androgenic. Lwm cov tshuaj zoo uas zoo sib xws rau pyrilamine yog CB-03-01, tseem hu ua Clascoterone. Vim tias aldosterone inhibits androgen receptors hauv cov qog sebaceous thiab cov hauv paus plaub hau, nws txo DHT. KX 826 hmoov ua haujlwm zoo ib yam thiab suav tias yog qhov nrawm tshaj plaws androgen receptor antagonist, thib ob rau CB-03-01. Raws li ib qho ntawm peb cov khoom nrov tshaj plaws, pyrilamine hmoov tau txais ntau cov lus pom zoo thiab cov lus pom zoo los ntawm kev lis kev cai. Dab tsi nyiam cov neeg siv khoom feem ntau yog qhov zoo. Tsuas yog tias, peb muaj tus nqi sib tw heev. Yog tias koj xav paub ntau ntxiv txog nws, tsuas yog hu rau Xi'an Sonwu Biotech Co., ltd.

Certificate Of Analysis

Yuav Pyrilutamide KX-826

Xi'an Sonwu Biotech Co. Ltd. muaj kev paub dhau los hauv kev lag luam thoob ntiaj teb thiab kev lag luam kev noj qab haus huv. Insisting rau txoj kev ntseeg raws li kev ntseeg thiab zoo ua ntej yog peb lub tuam txhab txoj cai. Peb nruj me ntsis tswj cov khoom zoo, uas txhais tau tias kev xaiv pib los ntawm raw khoom. Tsis tas li ntawd, peb tswj txhua qhov kev nthuav dav thiab txo cov nqi mus rau qhov siab tshaj plaws kom peb cov neeg siv khoom tuaj yeem tau txais cov khoom lag luam zoo. Raws li cov no, cov neeg siv khoom tau muab ntau cov lus pom zoo txog peb cov khoom. Yog li nrhiav Xi'an Sonwu Biotech Co. Ltd. thaum yuav nws.

Xi'an Sonwu thaum kawg ua kom cov khoom zoo yog li cov qauv tuaj yeem muab tau. Ntawm no yog qhov ntau.

Cov neeg siv khoom 'Cov lus pom zoo

Yuav Thov Li Cas Pyrilutamide

1. Ntau qhov kev tshawb fawb tam sim no hais txog kev siv ntawmKX826 hmoovtsom rau ob qho tib si kev nyab xeeb thiab kev ua tau zoo ntawm qhov sib xyaw. Kev tshawb fawb paub zoo tau siv 120 tus neeg koom nrog kev sim tsiaj thiab muab lawv xaiv ntawm peb qhov sib txawv: 2.5 mg ob zaug ib hnub, 5 mg ib hnub ib zaug, 5 mg ob zaug ib hnub, lossis pab pawg placebo. Lub hom phiaj thaj tsam plaub hau suav (TAHC) tau siv los suav cov txiaj ntsig tom qab kev sim 24-lub lim tiam. Txoj kev tshawb no xaus lus tias 5 mg ntawm pyrilamine noj ob zaug ib hnub twg yog qhov txiaj ntsig zoo tshaj plaws rau kev ua tiav qhov siab tshaj plaws ntawm cov plaub hau loj hlob. Muaj qhov nce ntawm 22.73 cov plaub hau ib square cent dhau lub hauv paus TAHC thiab 15.34 plaub hau ib square cent saum toj no TAHC ntawm cov placebo pawg raws li qhov tshwm sim ntawm qhov koob tshuaj no. Kev ua tau zoo ntawm pyrilamine yog pom tseeb rau txhua tus. Niaj hnub no tib neeg feem ntau nug cov ntaub ntawv txog nws. Thiab feem ntau cov neeg siv nyiaj ntau los kho cov plaub hau. Thaj, pyrilamine ua qhov sib txawv loj hauv lawv txoj kev kho mob. Cov plaub hau poob yog ib qho kev txhawj xeeb rau ntau tus neeg laus. Txawm hais tias nws tsis ua rau tsis xis nyob, nws muaj kev cuam tshuam loj rau tib neeg lub siab. Thiab ntau qhov kev sim tau pom tias cov plaub hau poob muaj kev cuam tshuam zoo rau tib neeg lub cev thiab lub hlwb. Qee tus neeg txawm muaj teeb meem pw tsaug zog thiab tsis tuaj yeem mloog zoo rau kev ua haujlwm vim tias plaub hau poob. Cov tshuaj tuaj yeem txav mus rau theem tom ntej ntawm kev sim raws li cov ntaub ntawv tseem ceeb ntawm cov tshuaj uas tau txais thoob plaws hauv txoj kev tshawb no.

2. Pyrilamine trials 'theem III thiab theem II tau zoo heev. Nyob rau lub sijhawm ntawm 24- lub sijhawm kho mob lub lim tiam, 416 tus neeg koom tau raug soj ntsuam, thiab kev hloov pauv ntawm TAHC tau siv los suav cov kev tshawb pom. Cov koob tshuaj uas cov kws tshawb fawb tab tom tshawb nrhiav rau theem III tsis tau tshaj tawm rau pej xeem, tab sis qhov kev tshawb pom ua ntej tau txhawb nqa thiab taw qhia txog kev txhim kho ntxiv hauv cov theem kev sim tshuaj. Piv rau ob theem dhau los, cov neeg koom nrog kev xeem ntau dua suav nrog hauv Phase III. Qhov no ua rau nws ua tau rau cov kws tshawb fawb los sau cov ntaub ntawv los ntawm cov qauv loj dua, uas thaum kawg ua rau cov ntaub ntawv meej dua ntawm kev nyab xeeb thiab kev ua tau zoo. Dutasteride thiab Clascoterone, ob qho tshuaj zoo li cov plaub hau poob ntawm kev ua lag luam-hais luv luv tham saum toj no-yog muab piv rau pyrilamine. Cov kws tshawb fawb feem ntau tau sau tseg tias cov tshuaj no muaj cov txheej txheem physiological sib txawv, tab sis lawv cov teebmeem zoo sib xws. Muab hais tias ob qho tib si dutasteride thiab clascoterone tau tshawb fawb zoo thiab tsim cov kev kho mob, muaj kev cia siab tias pyrilamine yuav sai sai no yog ib qho tshuaj nquag siv rau androgenic alopecia. Sib nrug los ntawm kev tshawb fawb pyrilamine, Kintor Pharma tau pib tshawb fawb soj ntsuam rau GT20029. Cov tshuaj no yog npaj los kho cov plaub hau poob. Thaum pyrilamine yog androgen receptor antagonist, cov tshuaj no xav tias yog ib qho androgen receptor degrader. AR degraders siv E3 ubiquitin ligase txoj hauv kev los khi nrog receptors thiab rhuav tshem cov qauv kev ncaj ncees. Yog li ntawd, tsawg androgen raug tsim.

3. KX 826 hmoov ua haujlwm raws li androgen receptor blocker los ntawm tshwj xeeb tsom rau androgen receptors. Qhov tseem ceeb, nws yog hom DHT blocker. Nws yog qhov txawv, txawm li cas los xij, los ntawm lwm yam DHT blockers, xws li finasteride thiab dutasteride, uas tam sim no tau muab tshuaj los kho androgenetic alopecia. Cov tshuaj hormone dihydrotestosterone los ntawm testosterone. Androgenetic alopecia feem ntau tshwm sim los ntawm nws. Hauv cov hauv paus plaub hau, DHT khi rau androgen receptors, shrinking cov hauv paus hniav thiab nws thiaj li ua rau cov plaub hau poob. Pyrilamine ua haujlwm los ntawm kev tiv thaiv cov enzyme 5-alpha-reductase los ntawm kev hloov testosterone rau hauv DHT los ntawm kev ua haujlwm. KX-826 aims kom qeeb lossis nres qhov me me ntawm cov hauv paus plaub hau los ntawm kev txo qis DHT, uas tuaj yeem khaws cov plaub hau uas twb muaj lawm thiab txhawb cov plaub hau regrowth. Finasteride thiab dutasteride ua haujlwm li DHT blockers los ntawm kev tsom mus rau 5-reductase enzyme uas hloov testosterone rau hauv DHT es tsis yog androgen receptors. Ob qho tib si dutasteride thiab finasteride feem ntau yog noj hauv qhov ncauj, thiab hauv qee tus neeg mob, lawv yuav muaj cov kev mob tshwm sim. Rau kev kho mob ntawm cov plaub hau poob, pyrilamine, tshuaj pleev ib ce, yuav yog ib qho kev xaiv zoo dua rau cov neeg uas tsis tuaj yeem noj qhov ncauj finasteride lossis dutasteride yam tsis muaj kev pheej hmoo. Txij li tam sim no tsis muaj DHT blockers muaj ntawv tso cai rau kev kho cov poj niam qauv plaub hau poob, KX-826 muaj cov kev kho tshwj xeeb tshwj xeeb rau cov poj niam. Nco ntsoov tias txhua tus neeg teb qhov sib txawv rau pyrilamine Powder cov txiaj ntsig kho plaub hau. Nws raug nquahu kom hais lus nrog tus kws kho mob kom paub qhov tseeb thiab cov lus qhia txog kev ua haujlwm zoo tshaj plaws rau kev kho cov plaub hau. Thiab ntau qhov kev sim tau pom tias cov plaub hau poob muaj kev cuam tshuam zoo rau tib neeg lub cev thiab lub hlwb. Qee tus neeg txawm muaj teeb meem pw tsaug zog thiab tsis tuaj yeem mloog zoo rau kev ua haujlwm vim tias plaub hau poob.

Hoobkas ib puag ncig

Xi'an Sonwu ntau lawm Hoobkas yog zoo-tsim, huv si, thiab huv si, nrog txaus Tshuag. Raws li kev coj noj coj ua ntawm lub tuam txhab, cov kws tshawb fawb tau hais kom tsim cov khoom tshiab. Cov hauv qab no yog qhov chaw sim ntawm peb lub chaw soj nstuam, cov cuab yeej ntsuas qib siab, thiab cov kws tshaj lij kev sim, nrog tus cwj pwm nruj los muab cov ntaub ntawv tseem ceeb rau peb cov khoom thiab muab peb cov neeg siv khoom zoo.

Daim ntawv pov thawj

Ntim

Cov ntaub ntawv logistics

Ntxiv nrog rau kev lees paub cov khoom zoo, lwm qhov tseem ceeb tshaj plaws yog cov neeg tuaj yeem tau txais cov khoom lag luam zoo. Yog li, Xi'an Sonwu muab txhua yam kev xa khoom raws li kev xav tau sib txawv.

Vim Li Cas Xaiv Peb

Xi'an Sonwu tau koom nrog ntshuam-export rau ntau tshaj 10 xyoo thiab muaj kev nplua nuj nyob hauv kev lag luam ntshuam thiab xa tawm.

Xi'an Sonwu muaj 10 xyoo dhau los ntawm kev tsim khoom, tsim khoom, thiab muag khoom.

Xi'an Sonwu muaj pab pawg tshaj lij nrog kev faib ua haujlwm kom meej.

Xi'an Sonwu muaj cov chaw ua haujlwm tshaj lij thiab cov khoom siv los xyuas kom meej cov khoom zoo. Cov khoom raug kuaj los ntawm cov neeg thib peb.

Xi'an Sonwu muab kev pabcuam OEM thiab 7 * 24 cov neeg siv khoom.

Yog xav yuavKX826 hmoov, thov hu rau Xi'an Sonwu.

E-mail:sales@sonwu.com

Cim npe nrov: kx826 hmoov, Tuam Tshoj, lwm tus neeg, manufacturers, hoobkas, lag luam wholesale, yuav, nqe, tej, ntshiab, raw, mov, kev muag khoom