Xi'an Sonwu Biotech Co., Ltd. yog ib qho ntawm cov kws tshaj lij thiab cov neeg muag khoom ntawm pp405 hmoov hauv Suav teb. Peb sov siab txais tos yuo rau cov lag luam wholesale bulk pp405 hmoov muag ntawm no los ntawm peb lub hoobkas. Cov khoom zoo thiab tus nqi tsim nyog muaj.
JXL-069 hmoov
PP405 hmoov(tseem hu ua JXL-069) yog ib qho kev sim plaub hau-cov neeg siv tshuaj poob tam sim no hauv kev tshawb fawb thaum ntxov. Nws tau txais kev saib xyuas tseem ceeb hauv xyoo tas los no feem ntau vim tias nws siv cov txheej txheem ntawm kev ua haujlwm txawv ntawm cov tshuaj kho cov plaub hau, muab tso rau nws raws li qhov muaj peev xwm txuas ntxiv mus rau kev kho mob androgenetic alopecia (AGA). Kev tshawb fawb rau PP405 tsom rau kev tswj hwm "lub xeev metabolic" ntawm cov plaub hau follicle qia hlwb es tsis yog ntawm cov qauv siv xws li kev hloov kho hormonal lossis txhim kho cov ntshav ntws. Cov kev kho mob ib txwm zoo li finasteride txo cov plaub hau follicle miniaturization los ntawm inhibiting dihydrotestosterone (DHT), thaum minoxidil prolongs cov plaub hau kev loj hlob theem los ntawm vasodilation thiab stimulation ntawm kev loj hlob teeb liab. Hauv qhov sib piv, PP405 siv txoj hauv kev sib txawv, tsom mus rau "rov ua cov hauv paus plaub hau ntawm qib cellular zog."
Hauv lwm lo lus, es tsis yog "txhim kho plaub hau kev loj hlob," JXL-069 nrhiav "rov pib dormant plaub hau follicles." Qhov kev hloov tshiab no tshwm sim los ntawm qhov tseeb tias nws tsis ua ncaj qha rau txoj hauv kev androgen tab sis hloov mus rau hauv cov plaub hau follicle lub neej voj voog ntawm qib cellular metabolism. Raws li txoj cai, cov txheej txheem no tuaj yeem siv rau ntau hom plaub hau poob, txawm tias loj - nplai, cov ntaub ntawv kho mob mus sij hawm ntev tam sim no tsis muaj. Xi'an Sonwu tuaj yeem muab raw JXL-069; thov hu rau lawv yog tias koj txaus siab.
Kev Xeem Thib Peb
PP 405 Qhov Yuav Yuav
Xi'an Sonwu Biotech Co., Ltd. muaj kev paub nplua nuj hauv kev lag luam thoob ntiaj teb thiab kev lag luam kev noj qab haus huv. Hais rau kev ntseeg-raws li thiab zoo- ua ntej raws li lub tuam txhab cov hauv paus ntsiab lus. Xi'an Sonwu nruj me ntsis tswj cov khoom zoo, uas txhais tau tias kev xaiv pib nrog raw cov ntaub ntawv. Tsis tas li ntawd, Xi'an Sonwu tswj txhua qhov kev nthuav dav thiab txo cov nqi kom cov neeg siv khoom tau txais tus nqi- cov khoom siv tau zoo. Raws li qhov no, cov neeg siv khoom tau muab tswv yim zoo heev rau cov khoom. Yog li nrhiav Xi'an Sonwu Biotech Co., Ltd. thaum yuav JXL-069 hmoov.
Xi'an Sonwu tuaj yeem ua kom cov khoom lag luam zoo, tso cai rau kev xa khoom. Ntawm no yog qhov ntau.
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Daim ntawv |
Tus Qauv Zauv |
MOQ |
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Hmoov |
10g |
10g |
Cov neeg siv khoom 'Cov lus pom zoo
PP405 Kev kho plaub hau
PP405 hmoovfeem ntau yog npaj rau kev kho mob ntawm androgenetic alopecia, tus cwj pwm los ntawm M-zoo li cov plaub hau rov qab los yog thinning ntawm lub kaus mom. Nws cov txheej txheem tseem ceeb tsis koom nrog "inhibiting plaub hau poob" hauv kev txiav txim siab ib txwm; es, nws lub hom phiaj ncaj qha reactivate dormant cov hauv paus plaub hau, ua kom lawv rov- nkag mus rau theem kev loj hlob thiab tsim cov plaub hau tshiab. Thaum lub sij hawm kev loj hlob ntawm cov plaub hau poob, ntau follicles tsis ploj tag nrho tab sis hloov mus rau lub sij hawm so, shrinking ho thiab tsis ua rau pom cov plaub hau. Qhov tseem ceeb ntawm PP405 yog nyob rau hauv nws lub peev xwm los tsom cov "tseem tau tsis tau ua tsis tau" cov hauv paus hniav thiab sim rov qab kho lawv txoj kev loj hlob. Yog li ntawd, nws raug cais raws li lub tswv yim hauv paus hauv "cov tshuaj kho dua tshiab" lossis "follicle reactivation," nws txawv ntawm cov kev kho tshuaj hormonal.
Cov ntaub ntawv los ntawm pej xeem muaj nyob rau thaum ntxov- theem kev sim tshuaj (feem ntau Theem 1 thiab Theem 2a) qhia tias cov cim qhia ntawm cov plaub hau regrowth tau pom tom qab luv luv - siv JXL-069. Cov txheej txheem kev tshawb fawb ib txwm muaj cov ntawv thov txuas ntxiv rau kwv yees li plaub lub lis piam, ua raws li ntau-lub lim tiam ua raws- lub sijhawm nce. Hauv cov kev sim me me uas muaj kwv yees li 70 txog 80 tus neeg tuaj koom, ib pawg ntawm cov ntsiab lus tau pom tias muaj qhov pom ntawm cov plaub hau ntom ntom ntawm yim-lub lim tiam. Kev tshawb pom dav dav yog tias, nyob rau hauv pab pawg kho mob, kwv yees li 31% ntawm cov txiv neej uas muaj nruab nrab - mus rau - plaub hau poob hnyav tau ua tiav ntau dua 20% nce ntawm cov plaub hau ceev hauv lub sijhawm luv. Hauv qhov sib piv, tsis muaj kev hloov pauv li no tau pom hauv pawg placebo. Tsis tas li ntawd, qhov tshwm sim ntawm "cov plaub hau ntev" (thicker, darker strands)-as opposed to fine, wispy vellus hairs- tau sau tseg nyob rau hauv tej thaj chaw; Qhov no suav hais tias yog qhov tseem ceeb, raws li nws qhia txog qhov rov nkag ntawm cov follicles mus rau theem kev loj hlob es tsis yog tsuas yog ib qho kev cuam tshuam stimulatory.
Dab tsi yog Mechanism Ntawm Kev Ua Ntawm PP405 Hauv Cov plaub hau
Hais txog nws cov txheej txheem ntawm kev ua, JXL-069 feem ntau yog tsom rau mitochondrial pyruvate carrier (MPC). Cov kab ke no, tsim los ntawm MPC1 thiab MPC2 protein subunits, yog nyob rau hauv mitochondrial membrane thiab feem ntau thauj pyruvate los ntawm cytoplasm mus rau mitochondria. Pyruvate nkag mus rau mitochondria thaum lub sij hawm ib txwm cellular metabolism thiab koom nyob rau hauv oxidative phosphorylation thiab lub tricarboxylic acid voj voog, ua ib tug tseem ceeb npaum li cas ntawm ATP uas ua hauj lwm raws li lub cell thawj lub zog. Cov txheej txheem no, uas yog lub zog tseem ceeb rau ntau lub hlwb nyob rau hauv ib qho chaw so lossis ruaj khov, yog ib qho piv txwv ntawm "oxidative metabolism" hom. PP405 inhibits qhov kev thauj mus los tseem ceeb. Thaum MPC yog inhibited, pyruvate tsis tuaj yeem nkag mus rau mitochondria, yog li txwv tsis pub nkag mus rau hauv mitochondrial oxidative metabolic txoj kev; Yog li ntawd, lub cell raug yuam kom hloov ntau pyruvate mus rau cytoplasmic lactate fermentation txoj kev-tseem ceeb txhawb glycolysis. Qhov kev hloov pauv hauv cov txheej txheem metabolic no ua rau muaj kev hloov pauv tseem ceeb hauv lub cev tag nrho lub zog thiab cov txheej txheem metabolite, tshwj xeeb tshaj yog nce qib lactate thiab rov ua kom lub cev rov ua haujlwm hauv lub cev. Biologically, cov txheej txheem no hu ua "metabolic reprogramming."
Nyob rau hauv cov plaub hau follicle system, qhov no metabolic reprogramming yog suav hais tias tseem ceeb heev. Cov hauv paus plaub hau tsis yog cov ntaub so ntswg uas loj hlob tsis tu ncua; Hloov chaw, lawv tau dhau mus ua ntu zus suav nrog anagen (kev loj hlob), catagen (regression), thiab telogen (so) theem. Thaum lub sij hawm kev loj hlob ntawm androgenetic alopecia, ntau cov hauv paus plaub hau maj mam nkag mus rau lub sijhawm so, nrog rau kev ua haujlwm me me- qhov twg cov plaub hau ntawm cov plaub hau ua nyias thiab luv dua - nws thiaj li tsis tsim cov plaub hau yuav luag tag. Txawm li cas los xij, kev tshawb fawb qhia tias cov "so" follicles feem ntau khaws cov plaub hau follicle qia hlwb structurally; cov hlwb no tsuas yog ua haujlwm tsis zoo lossis tsis ua haujlwm, txhais tau tias lawv theoretically khaws lub peev xwm rau kev tsim dua tshiab.
Hoobkas ib puag ncig
1. Xi'an Sonwu Biotech Co., Ltd muaj nws lub Hoobkas, yog li nws muaj cov khoom tsim nyog. Tsis tas li, Xi'an Sonwu muaj chav ua haujlwm huv, huv si nrog cov khoom siv siab heev. Cov kws tshawb fawb niaj hnub tsim cov khoom tshiab raws li Xi'an Sonwu cov lus qhia kom ua tau raws li cov neeg siv khoom xav tau.
2. Xi'an Sonwu Biotech Co., Ltd muaj cov cuab yeej ntsuas qib siab thiab cov kws tshaj lij, uas txhua tus qhia tias Xi'an Sonwu lub hom phiaj muab cov ntaub ntawv raug thiab ua tau zoo thiab kev pabcuam zoo.
Daim ntawv pov thawj
Ntim
Logistics
Dhau li lav cov khoom, lwm qhov tseem ceeb tshaj plaws yog cov neeg siv khoom tuaj yeem tau txais cov khoom zoo. Yog li, Xi'an Sonwu muaj ntau yam ntawm cov neeg xa xov tuaj yeem ua tau raws li qhov xav tau sib txawv.
FAQ
Hais txog kev nyab xeeb, ib qho tseem ceeb ntawm JXL-069 yog nws daim ntawv thov tshuaj pleev ib ce, uas ua rau muaj qhov tsis txaus ntseeg hauv lub cev. Cov kev sim tshuaj tau kuaj pom tsis muaj qhov tseem ceeb ntawm cov tshuaj nkag mus rau hauv cov hlab ntsha, thiab tsis muaj cov kev mob tshwm sim loj heev tau tshaj tawm. Qhov no sib piv nrog qee cov tshuaj tiv thaiv qhov ncauj (xws li finasteride), qhia txog qhov muaj txiaj ntsig zoo dua kev nyab xeeb.
Txawm li cas los xij, nws yog ib qho tseem ceeb uas yuav tsum tau hais tias PP405 tseem yog ib qho tshuaj ntsuam xyuas; nws tseem tsis tau ua tiav Phase III qhov kev sim tshuaj kho mob lossis tsis tau txais kev pom zoo ua lag luam los ntawm ib lub koom haum tswj hwm hauv tebchaws. Yog li ntawd, thaum nws qhia tau hais tias "cov cim zoo thaum ntxov," nws tseem tsis tuaj yeem sib npaug nrog kev tsim, pov thawj kev kho mob.
Los ntawm kev xav txog kev tshawb fawb, JXL-069 lub luag haujlwm hauv kev kho cov plaub hau poob tuaj yeem raug sau tseg raws li hauv qab no: nws yog cov tshuaj pleev xim rau cov tshuaj metabolic-modulating tam sim no nyob rau hauv kev tshuaj xyuas. Los ntawm kev cuam tshuam lub zog ntawm cov plaub hau follicle qia hlwb, nws lub hom phiaj "ua kom dormant plaub hau follicles." Cov tshuaj tseem tab tom tshawb fawb thiab txhim kho. Nws tseem tsis tau pom zoo raws li kev kho mob ib txwm, txawm tias kev sim tshuaj thaum ntxov qhia nws lub peev xwm los txhawb cov plaub hau kev loj hlob thiab ua kom cov plaub hau ceev.
Yog koj xav yuavPP405 hmoovlossis txaus siab rau Xi'an Sonwu, lossis muaj lwm yam lus nug txog cov khoom, tsis txhob yig tiv tauj Xi'an Sonwu.
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