5 Aminolevulinic Acid Phosphate

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5 Aminolevulinic acid phosphate, tseem hu ua 5-ALA phosphate, yog phosphate daim ntawv ntawm 5-Aminolevulinic acid. 5-ALA yog ib txwm tshwm sim tsis muaj protein ntau amino acid nyob rau hauv cov kab mob muaj sia, thiab nws kuj yog tus thawj coj ntawm biosynthesis ntawm tetrapyrrole tebchaw, xws li, chlorophyll, heme thiab vitamin B12. 5-ALA ua lub luag haujlwm ua tus neeg saib xyuas tus nqi txwv hauv heme biosynthesis thiab nws tuaj yeem txhim kho lub cev tiv thaiv kab mob ntawm penaeus vannamei rau vibrio parahaemolyticus, txhim kho lub cev tiv thaiv kab mob thiab tiv thaiv cov noob, thiab ua kom lub zog aerobic metabolism raws li. Tam sim no, nws tau siv dav hauv kev ua liaj ua teb thiab tshuaj kho mob. Vim nws cov nyhuv zoo, 5-Aminolevulinic acid cov neeg muag khoom tshwm sim hauv khw maj mam. Raws li ib qho ntawm lawv, Xi'an Sonwu tuaj yeem muab cov khoom zoo 5-Amino-4-oxopentanoic acid phosphate hmoov. Lub purity yog tsawg dua 98 feem pua. Yog tias koj xav paub ntau ntxiv txog cov khoom no, thov hu rau Xi'an Sonwu.

Certificate of Analysis

Kev kuaj HPLC

5-ALA Mechanisms

Ua kom thiab nce ntawm mitochondria

5-ALA yog ib txwm tshwm sim hauv kab mob, thiab tsim los ntawm mitochondria. Yog li peb hais mitochondria yog cov organelles hauv cell uas tsim 5-ALA. Nws lub luag haujlwm mian yog tsim lub zog los ntawm zaub mov thiab oxygen. Muaj "kev ua pa nyuaj" nyob rau hauv mitochondria, thiab heme ua nyob rau hauv mitochondria ua raws li lub active centre ntawm lub pa saw complex.

Hauv kev tshawb fawb. Cov kws tshawb fawb pom tias muaj peev xwm tsim lub zog ntawm mitochondrial tau txhim kho hauv cov tsiaj uas tau muab rau 5-ALA. Cov kab mob ua pa nyuaj ua haujlwm los hloov cov khoom noj los ntawm lub zog rau hauv hluav taws xob, tsim cov tshuaj hu ua adenosine triphosphate (ATP) uas yog lub zog ntawm lub neej ua haujlwm. Vim tias ATP tuaj yeem nkag siab tias yog cov nyiaj hauv kev lag luam, ATP tseem hu ua "lub zog txiaj rau cov kab mob muaj sia." 5-ALA tau txais txiaj ntsig los txhim kho ATP no.

Kev kuaj mob qog nqaij hlav thiab kev kho mob

Kev tsim cov heme los ntawm 5-ALA yog ua tiav los ntawm kev khi hlau rau hauv qhov chaw. Ib yam khoom hu ua protoporphyrin IX (PpIX) yog tsim nyob rau hauv ib kauj ruam ua ntej cov hlau ua ke thiab muaj cov khoom tshwj xeeb. Thaum illuminated nrog ib tug tshwj xeeb wavelength ntawm xiav lub teeb, nws qhia txog lub teeb liab.

Cov qog hlwb yog cov hlwb zoo tib yam uas tau dhau los ua DNA hloov pauv thiab tau txais lub peev xwm loj hlob mus tas li. Nws tau pom tias cov qog hlwb uas tau nqus tau ntau ntawm 5-ALA tsis tuaj yeem tsim heme ib txwm tab sis PpIX tau sau ua ntej. Vim yog qhov no thiab cov cuab yeej ntawm PpIX, muab 5-ALA rau cov kab mob thiab teeb pom kev zoo nrog lub teeb xiav xiav yuav pab kws kho mob nrhiav seb cov qog nqaij hlav nyob qhov twg. Qhov no yog qhov tseem ceeb rau kev kuaj xyuas cov me me uas tsis tuaj yeem pom ntawm qhov muag liab qab, uas yog hu ua photodynamic diagnosis (PDD).

Anti-oxidation thiab tiv thaiv kab mob los ntawm degrading heme

Txawm hais tias heme muaj ntau yam haujlwm, nws kuj tuaj yeem ua rau cov kab mob lom yog tias tsim cov pa oxygen reactive (ROS) hauv thaj chaw uas nws yuav tsum tsis txhob ua. Txhawm rau tswj lossis zam cov khoom no, peb lub cev yuav tsim cov enzyme hu ua heme oxygenase-1 (HO-1).

HO-1decomposes ntau heme kom tswj kom muaj nuj nqis tas li ntawm heme hauv lub cev. Interestingly, bilirubin thiab carbon monoxide tsim los ntawm degraded heme, muaj cov nyhuv ntawm tshem tawm reactive oxygen hom.

Feem ntau ntawm cov loj npaum li cas ntawm5 Aminolevulinic acid phosphatemuab rau tsiaj yuav tsis remian nyob rau hauv lub cev li heme. Thiab cov kws tshawb fawb tau kawm tias qee qhov 5-ALA hauv cov ntshav tuaj yeem hloov mus rau bilirubin tam sim ntawd los ntawm HO-1 ntawm heme. Raws li qhov no, 5-ALA muaj cov nyhuv antioxidant zoo lossis cuam tshuam rau kev tshem tawm ROS, los ntawm induing HO-1 thiab tsim bilirubin thiab carbon monoxide.

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Tuam txhab Profile

Xi'an Sonwu Biotech Co. Itd yog cov kws tshaj lij Suav chaw tsim khoom thiab cov khoom lag luam, nrhiav tau nyob rau hauv 2012, thiab nyob rau hauv Hi-Tech industrial Zone Xi'an nroog, Shannxi xeev, Suav. Xi'an Sonwu them tag nrho cov xim rau kev txhim kho, kev tshawb fawb thiab tsim cov khoom noj khoom haus additives, cog extract, APl thiab lwm yam khoom xyaw ntawm cov khoom kho mob. Xi'an Sonwu muab tsib yam khoom siv raw khoom: Cov plaub hau poob Powders, Nootropic, API, Cov Khoom Siv Muscle, Cog Extract. Xi'an Sonwu ua siab dawb ntseeg tias qhov chaw ntawm kev koom tes zoo yog cov kev pabcuam zoo tshaj plaws thiab zoo. Yog li, txais tos koj qhov kev nug.

Yog tias koj txaus siab thiab xav yuav5 aminolevulinic acid phosphate, tsis txhob yig tiv tauj Xi'an Sonwu.

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