Bortezomib hmoov

Bortezomib yog dab tsi

Bortezomib hmoovtseem hu ua PS-341 Powder lossis MG-341 hmoov. MG-341 yog ib yam tshuaj siv los npaj kev txhaj tshuaj thiab feem ntau yog siv los kho cov kab mob tshwj xeeb, tshwj xeeb tshaj yog ntau yam teeb meem myeloid thiab mantle cell lymphoid. MG-341 belongs rau ib chav kawm ntawm cov tshuaj hu ua proteasome inhibitors, uas thaiv cov kev ua ntawm proteasome. Proteasomes yog cov enzyme complexes hauv cov hlwb uas zom cov proteins uas tsis xav tau lossis ua rau lawv puas tsuaj. Bortezomib ua rau tsub zuj zuj ntawm cov proteins los ntawm inhibiting proteasomes, uas tuaj yeem ua rau cov cell tuag, tshwj xeeb tshaj yog cov kab mob sib faib sai. Yog tias koj xav tau, Xi'an Sonwu tuaj yeem muab bortezomib. Xi'an Sonwu tos ntsoov yuav hnov ​​​​los ntawm koj.

Certificate Of Analysis

Bortezomib Nqe

Xi'an Sonwu Biotech Co. Ltd. muaj kev paub dhau los hauv kev lag luam thoob ntiaj teb thiab kev lag luam kev noj qab haus huv. Insisting rau txoj kev ntseeg raws li kev ntseeg thiab zoo ua ntej yog peb lub tuam txhab txoj cai. Peb nruj me ntsis tswj cov khoom zoo, uas txhais tau tias kev xaiv pib los ntawm raw khoom. Tsis tas li ntawd, peb tswj txhua qhov kev nthuav dav thiab txo cov nqi kom siab tshaj plaws kom peb cov neeg siv khoom tuaj yeem tau txais cov khoom lag luam zoo. Raws li cov no, cov neeg siv khoom tau muab ntau cov lus pom zoo txog peb cov khoom. Yog li nrhiav Xi'an Sonwu Biotech Co. Ltd. thaum yuav nws.

Xi'an Sonwu ua kom cov khoom zoo thiab tuaj yeem muab cov qauv. Ntawm no yog qhov ntau.

Cov neeg siv khoom zoo lus

Bortezomib Mechanism Of Action

Bortezomib yog ib qho proteasome inhibitor feem ntau siv los kho ntau yam myeloid thiab mantle cell lymphoid teeb meem. Nov yog qhov tseem ceeb ntawm nws txoj haujlwm:

A. Mechanism of Action

1. Proteasome Inhibition:

PS-341 inhibits 26S proteasome, ib qho nyuaj uas degrades ubiquitinated proteins hauv hlwb.

Proteasomes yog qhov tseem ceeb hauv kev tswj hwm cov protein homeostasis los ntawm kev rhuav tshem cov proteins uas tsis tsim nyog.

2. Kev cuam tshuam ntawm cov txheej txheem ntawm tes:

PS-341 tiv thaiv kev degradation ntawm cov proteins no los ntawm inhibiting proteasome, uas ua rau lawv nyob rau hauv lub hlwb.

Qhov kev txuam no cuam tshuam ntau yam txheej txheem ntawm tes, suav nrog kev tswj hwm lub voj voog ntawm tes, apoptosis (programmed cell tuag), thiab kev ntxhov siab.

3. Induces Apoptosis:

Kev sib sau ntawm cov proteins hauv cov hlwb tuaj yeem ua rau muaj kev ntxhov siab thiab ua haujlwm tsis zoo, tshwj xeeb tshaj yog hauv kev faib cov qog nqaij hlav sai.

Qhov kev ntxhov siab no ua rau apoptosis, xaiv qhov ua rau tuag ntawm cov kab mob hauv lub cev thaum sparing feem ntau cov hlwb.

B. Kev siv tshuaj kho mob

1. Ntau yam teeb meem Myeloid:

PS-341 yog siv los kho ntau yam teeb meem myeloid, feem ntau ua ke nrog lwm cov tshuaj xws li dexamethasone lossis lenalidomide. Nws pab txo tus naj npawb ntawm cov kab mob hauv cov pob txha pob txha thiab tswj kev loj hlob ntawm tus kab mob.

2. Mantle Cell Lymphatic Teeb meem:

Mantle cell lymphatic teeb meem kuj tau kho nrog cov pob txha pob txha, tshwj xeeb tshaj yog nyob rau hauv cov neeg mob uas nws mob tau rov qab los lossis tsis teb rau cov kev kho mob ib txwm muaj.

PS-341 ua haujlwm los ntawm kev tsom thiab tua cov kab mob lymphatic, yog li txo qhov teeb meem loj thiab cov tsos mob.

C. Cov yam ntxwv ntxiv

1. Anti-angiogenic teebmeem:

PS-341 tau pom tias boratezomib muaj cov yam ntxwv ntawm cov tshuaj tiv thaiv angiogenic, uas tiv thaiv kev txhim kho cov hlab ntsha tshiab uas yuav txwv tsis pub muab qhov teeb meem nrog cov as-ham. Qhov no ntxiv pab kom tshaib plab cov kab mob ntawm cov as-ham thiab oxygen, yog li inhibiting lawv txoj kev loj hlob.

2. Immunomodulation:

PS-341 tuaj yeem hloov kho lub cev tiv thaiv kab mob, ua kom lub cev muaj peev xwm paub txog thiab tua cov kab mob.

PS-341 tuaj yeem cuam tshuam rau kev tsim tawm ntawm ntau lub cev tiv thaiv kab mob thiab cytokines, uas tuaj yeem ua rau nws txoj haujlwm tiv thaiv kab mob.

Kev siv Bortezomib

Bortezomib hmoovfeem ntau yog siv los kho tej yam mob. Nov yog nws cov kev siv tseem ceeb:

1. Ntau yam teeb meem myeloid: Bortezomib feem ntau siv los kho ntau yam teeb meem myeloid, mob pob txha plasma hlwb. Nws tuaj yeem siv los ua kev kho thawj zaug, ua ke nrog lwm cov tshuaj, lossis ua ib tus neeg sawv cev hauv cov neeg mob uas twb tau txais kev kho mob sib txawv.

2. Mantle cell lymphoma teeb meem: Lwm yam uas tsis yog-Hodgkin lymphoma uas kho nrog boratezolamib yog mantle cell lymphoma (MCL). MG-341 tuaj yeem siv rau hauv cov neeg mob uas tau txais tsawg kawg ib qho kev kho mob ua ntej.

Ntxiv nrog rau cov kev siv tseem ceeb no, MG-341 tej zaum yuav raug siv off-label lossis kawm hauv kev sim tshuaj rau lwm yam mob, suav nrog:

3. Lwm yam hematologic malignancies: MG-341 tau kawm rau lwm yam mob, xws li tej yam mob leukemia thiab lwm yam teeb meem lymphoma.

4. Cov teeb meem ntawm lub cev: MG-341 tam sim no tab tom kawm txog nws lub peev xwm los kho ntau yam teeb meem ntawm lub cev, txawm hais tias nws siv hauv cov xwm txheej no tsis meej dua li nws siv hauv cov kab mob hematologic.

5. Amyloidosis: MG-341 qee zaum siv los kho lub teeb-chain amyloidosis, ib yam kab mob uas txawv txav ntawm cov protein deposits (amyloid) nyob rau hauv cov ntaub so ntswg thiab lub cev.

Hauv kev kho mob, kev siv MG-341 tshwj xeeb yuav nyob ntawm tus neeg mob yam xwm txheej, suav nrog hom thiab theem ntawm tus mob, kev kho mob yav dhau los, thiab kev noj qab haus huv tag nrho.

Cov teebmeem ntawm Bortezomib

Zoo li ntau cov tshuaj khomob, boratezomib tuaj yeem muaj ntau yam teebmeem. Txhua tus neeg mob yuav ntsib cov kev mob tshwm sim no mus rau qhov sib txawv ntawm qhov hnyav. Nov yog qee qhov kev mob tshwm sim thiab hnyav cuam tshuam nrog MG-341:

Cov teebmeem tshwm sim

1. qaug zog: Xav tias nkees nkees lossis qaug zog.

2. Cov teeb meem hauv plab hnyuv: suav nrog xeev siab, ntuav, raws plab, thiab cem quav.

3. Peripheral neuropathy: loog, tingling, lossis mob ntawm tes thiab ko taw.

4. Thrombocytopenia: Ib qho platelet suav tsawg tuaj yeem ua rau muaj kev pheej hmoo los ntshav thiab nqaij tawv.

5. Anemia: Cov qe ntshav liab tsawg ua rau qaug zog thiab qaug zog.

6. Neutropenia: Cov qe ntshav dawb tsawg ua rau muaj kev pheej hmoo kis mob.

7. Ua npaws: Qhov kub ntawm lub cev nce, feem ntau yog vim muaj kab mob los yog cov tshuaj tiv thaiv rau cov tshuaj.

8. Tsis qab los noj mov: Txo qab los noj mov tuaj yeem ua rau poob phaus.

9. Cov pob khaus: tawv nqaij khaus lossis pob khaus.

Mob hnyav heev

1. Teeb meem hauv plawv: suav nrog lub plawv tsis ua haujlwm thiab arrhythmias (lub plawv dhia tsis zoo).

2. Hepatotoxicity: Kev kuaj lub siab ua haujlwm tsis zoo qhia tau tias muaj peev xwm ua rau daim siab puas.

3. Cov teeb meem ntawm lub ntsws, xws li kab mob ntsws interstitial, uas tuaj yeem ua rau ua pa nyuaj.

4. Mob ntshav qab zib: mob hlab ntsha tawg tuaj yeem ua rau mob hnyav thiab txo qis kev txav mus los.

5. Hypotension: ntshav siab qis tuaj yeem ua rau kiv taub hau thiab qaug zog.

6. Cov kab mob hnyav: Vim muaj kev tiv thaiv kab mob, nrog rau mob ntsws thiab mob sepsis.

7. Kab mob plab hnyuv: Ib yam mob uas tsis tshua muaj tab sis loj heev uas muaj qhov tshwm sim hauv plab hnyuv.

Cov neeg mob kho nrog bortezomib yuav tsum tau saib xyuas zoo los ntawm lawv pab neeg kho mob los tswj cov kev mob tshwm sim thiab kho kho raws li xav tau. Cov neeg mob yuav tsum tau tshaj tawm cov tsos mob tshiab lossis tsis zoo rau lawv tus kws kho mob tam sim ntawd.

Hoobkas

1. Muaj cov khoom muag txaus ntawm Xi'an Sonwu qhov chaw. Tsis tas li ntawd, Xi'an Sonwu nta lub tuam tsev tsim khoom niaj hnub uas tau teeb tsa thiab tsis muaj dab tsi. Raws li kev coj ua ntawm kev lag luam, cov kws tshawb fawb tau tsim cov khoom tshiab los ua kom tau raws li cov neeg siv khoom xav tau.
2. Xi'an Sonwu siv zog ua kom tiav cov txiaj ntsig tau zoo thiab muaj txiaj ntsig zoo nrog rau kev pabcuam zoo, raws li tau lees paub los ntawm nws cov cuab yeej ntsuas kev txawj ntse thiab cov neeg ua haujlwm kuaj tau zoo.

Daim ntawv pov thawj

Ntim

Logistics Hloov tshiab

Ntxiv nrog rau kev lees paub cov khoom zoo, lwm qhov tseem ceeb tshaj plaws yog cov neeg tau txais cov khoom lag luam zoo. Yog li, Xi'an Sonwu muab txhua yam kev xa khoom raws li kev xav tau sib txawv.

FAQ

1. Yuav nug li cas?

Peb tuaj yeem hu xovtooj, email, lossis social media.

2. Koj tuaj yeem lav qhov khoom zoo li cas?

Txhua pawg yuav tsum tau sim, thiab COA tuaj yeem muab rau cov neeg siv khoom. Tsis tas li ntawd, tag nrho cov khoom dhau qhov kev xeem: HPLC, UV, GC, TLC, thiab lwm yam. Peb koom tes nrog cov neeg thib peb, zoo li SGS.

3. Koj ntim thiab khaws cia li cas?

Pob: Siv cov khoom ntim ntim khoom ntim thiab ntim cov ntawv ntim khoom ntim, lossis ntim cov khoom raws li cov neeg siv khoom xav tau.

Cia: Koj tuaj yeem khaws cia rau hauv qhov chaw qhuav thiab txias thiab ua kom tsis txhob tshav ntuj.

Yog koj xav paub txog lubbortezomib hmoov, koj tuaj yeem tiv tauj Xi'an Sonwu. Nyem rau email, thiab tom qab ntawd koj tau txais PS-341 hmoov zoo.

Email:sales@sonwu.com

Cim npe nrov: Bortezomib hmoov, Tuam Tshoj, lwm tus neeg, manufacturers, hoobkas, lag luam wholesale, yuav, nqe, tej, ntshiab, raw, mov, kev muag khoom