Clomiphene txhais li cas
Clomiphene citrate hmoov, tseem hu ua clomifene, belongs rau ib hom tshuaj tiv thaiv hormonal. Nws feem ntau yog siv los kho cov poj niam cev xeeb tub hauv cov poj niam uas tsis ovulate, suav nrog cov poj niam uas muaj mob polycystic zes qe menyuam. Cov tshuaj no muaj ob qho tib si tsis muaj zog agonistic thiab antagonistic cov teebmeem ntawm cov tshuaj estrogen, uas tuaj yeem txhawb nqa ovulation. Clinically, clomiphene feem ntau yog siv los kho cov poj niam cev xeeb tub anovulatory, thiab nws yog qhov tsim nyog rau cov neeg mob uas muaj qee theem ntawm estrogen hauv lub cev. Nws kuj tuaj yeem kho corpus luteum insufficiency thiab zes qe menyuam kuaj ua haujlwm. Tsis tas li ntawd, siv los kuaj xyuas qhov txawv txav ntawm tus txiv neej hypothalamus-pituitary-gonadal axis thiab kho txiv neej infertility vim phev tsawg dhau. Nyob rau hauv luv luv, cov tshuaj yog ib tug hluavtaws uas tsis yog-steroidal npaj nrog ib tug tshuaj qauv zoo ib yam li diethylstilbestrol. Nws yog ib qho tshuaj uas muaj zog tiv thaiv estrogen thiab tsis muaj zog estrogen nyhuv. belongs rau qeb ntawm "Ovulation Inducing Agents" hauv World Health Organization's Essential Medicines List. Nws advent ushered nyob rau hauv lub era ntawm pab reproductive technology. Yog tias koj xav tau clomiphene citrate nyoos, Xi'an Sonwu yuav tsum yog qhov kev xaiv zoo tshaj plaws.
Certificate Of Analysis
Yam khoom | Specification | Cov txiaj ntsig |
Qhov tshwm sim | Dawb hmoov | Ua raws |
Specification | 99% min | 99.32% ua |
Mesh Loj | 100% dhau 80 mesh | Ua raws |
Tshauv | Tsawg dua lossis sib npaug li 5.0 feem pua | 3.43 feem pua |
Poob rau ziab | Tsawg dua lossis sib npaug li 5.0 feem pua | 3.57% ua |
Melting point | 116 5-118 degree | Ua raws |
Tshuaj ntsuam xyuas | ||
Hnyav Hlau | Tsawg dua lossis sib npaug li 10.0 mg/kg | Ua raws |
Pb | Tsawg dua lossis sib npaug rau 2.0 mg/kg | Ua raws |
Raws li | Tsawg dua los yog sib npaug rau 1.0 mg/kg | Ua raws |
Microbiological Analysis | ||
Cov tshuaj tua kab residue | Tsis zoo | Tsis zoo |
Tag Nrho Phaj suav | Tsawg dua lossis sib npaug li 1000cfu / g | Ua raws |
Yeast & Pwm | Tsawg dua lossis sib npaug li 100cfu / g | Ua raws |
E.coil | Tsis zoo | Tsis zoo |
Salmonella | Tsis zoo | Tsis zoo |
Qhov twg yuav Clomiphene Citrate
Xi'an Sonwu Biotech Co., Ltd. yog ib lub lag luam nrog ntau tshaj kaum xyoo ntawm kev ua lag luam. Nws koom tes nrog cov teb chaws hauv Asmeskas, Europe, Asia, thiab Oceania thoob ntiaj teb. Xi'an Sonwu yeej ib txwm khaws qhov muag ntawm cov khoom zoo ua ntej. Txaus siab rau txhua tus neeg yuav khoom thiab ntsib txhua tus neeg siv khoom yog Xi'an Sonwu txoj kev nrhiav. Xi'an Sonwu nruj me ntsis tswj kev xaiv cov khoom siv raw thiab tsim cov khoom zoo, xws li kev tsim khoom, kev sim, thiab muag. Tsis tas li ntawd, Xi'an Sonwu siv zog ua txoj haujlwm zoo hauv txhua qhov kev nthuav dav thiab nrhiav kom tau cov neeg siv khoom kom tau txais cov khoom lag luam zoo. Raws li qhov zoo, kev muag khoom, thiab kev pab cuam tom qab muag, cov neeg siv khoom tau muab cov lus pom zoo rau cov khoom. Yog li yog tias koj xav tau clomiphene, tsis txhob yig tiv tauj Xi'an Sonwu.
Xi'an Sonwu tsis tsuas yog thaum kawg ua kom cov khoom zoo tab sis kuj muab cov qauv. Thov xyuas kom muaj nuj nqis.
Daim ntawv | Tus Qauv Zauv | MOQ |
Hmoov | 50g | 100g |
Cov neeg siv khoom 'Cov lus pom zoo
Clomiphene ua haujlwm li cas txhawm rau txhawm rau ovulation
Clomiphene yog ib qho tshuaj hormone, tab sis nws cov tshuaj pharmacological tseem tsis tau paub meej. Nws tuaj yeem ua haujlwm zoo ib yam li cov tshuaj estrogen. Nws khi rau cov tshuaj estrogen receptors hauv hypothalamus, sib tw nrog cov tshuaj estrogen rau cov receptors no, txo lawv cov teebmeem. Qhov kev khi no txhawb nqa kev txhawb nqa thiab kev tso tawm ntawm GnRH los ua kom ovulation thiab tseem tuaj yeem ua rau ntawm zes qe menyuam kom cov lus teb follicular rau gonadotropins.
Cov khoom no muaj ob qhov teebmeem ntawm qhov tsis muaj zog excitability thiab muaj zog antagonism ntawm estrogen. Nws ua rau hypothalamus thiab estrogen kev sib tw receptors los ntawm ib koob me me ntawm cov tshuaj, txo cov kev tawm tswv yim ntawm cov tshuaj estrogen, txhawb kev tso tawm ntawm endogenous GnRH, thiab txhawb kev tso tawm ntawm pituitary. Antagonism tuaj yeem nyiam cuam tshuam nrog cov teebmeem tsis zoo ntawm endogenous estrogen los ntawm kev sib tw ntawm cov tshuaj hypothalamic estrogen receptors thiab es tsis txhob txhawb kev tso tawm ntawm follicle-stimulating hormone thiab luteinizing hormone, yog li txhawb kev loj hlob ntawm follicle. Raws li cov follicles paub tab, estrogen tso tawm nce, stimulating preovulatory gonadotropin tso tawm kom ncov los ntawm kev tawm tswv yim zoo. Thaum clomiphene inhibited, GnRH txo qis, ua rau estradiol nce mus rau 2 lossis 3 npaug ntawm qhov nruab nrab. Qhov nce hauv estradiol txhawb nqa LH surge, uas ua rau ovulation.
Dab tsi yog Cov txiaj ntsig ntawm Clomiphene Citrate
Raws li cov ntaub ntawv tseem ceeb, qhov ua tiav ntawm clomiphene ovulation induction tau mus txog ze li 80 feem pua. Cov ntaub ntawv no yog ib qho surprise loj rau cov poj niam infertility cov neeg mob, tab sis qhov kev tu siab tsuas yog qhov qis cev xeeb tub. Raws li kev soj ntsuam, noj Lub caij nyoog ntawm cev xeeb tub nrog clomiphene tsuas yog kwv yees li 20 feem pua, yog vim li cas qee cov neeg mob tau ua tiav nrog clomiphene tab sis tsis xeeb tub.
Clomiphene citrate hmoovsiv kev kho mob los kuaj xyuas txiv neej hypothalamus-pituitary-gonad axis tsis ua haujlwm. Cov tshuaj no cuam tshuam rau kev kho cov txiv neej infertility vim cov phev tsawg dhau, yog li cov txiv neej tuaj yeem noj clomiphene.
Anovulatory poj niam infertility;
Cov poj niam uas tsis txaus corpus luteum muaj nuj nqi;
Ntsuam xyuas poj niam txoj haujlwm ntawm zes qe menyuam;
Kev kho tus txiv neej infertility vim phev tsawg dhau;
Kev txheeb xyuas qhov tsis ua haujlwm ntawm hypothalamic-pituitary-gonadal axis hauv cov txiv neej.
Dab tsi yog Cov Teeb Meem Ntawm Clomiphene
1. Cov kev phiv tshwm sim ntau dua muaj xws li o, mob plab, mob plab lossis plab plab, zes qe menyuam loj lossis cyst tsim lossis zes qe menyuam, thiab pom meej ntawm zes qe menyuam, feem ntau tshwm sim ob peb hnub tom qab tso tseg cov tshuaj.
2. Cov tsis tshua muaj tshwm sim yog: qhov muag tsis pom kev, pom ob lub qhov muag, lub teeb ci ntsa iab ntawm lub qhov muag, qhov muag tsis pom kev, tsis pom kev, thiab daj ntawm daim tawv nqaij thiab sclera.
3. Kev ceev faj yuav tsum tau them nyiaj thaum muaj cov tshuaj tiv thaiv hauv qab no: kub flashes, tsis xis nyob hauv lub mis, cem quav lossis zawv plab, kiv taub hau lossis kiv taub hau, mob taub hau, mob plab zuj zus lossis los ntshav tsis zoo, qab los noj mov thiab qhov hnyav nce, plaub hau poob, kev nyuaj siab, ntxhov siab, tsis xis nyob. , insomnia, qaug zog, xeev siab thiab ntuav, daim tawv nqaij ua pob khaus, ua xua dermatitis, wheal, nquag tso zis, thiab lwm yam, kuj tuaj yeem ua rau poob phaus. Muaj tsawg heev qhia txog mob qog noj ntshav mis thiab qog nqaij hlav qog nqaij hlav txawv teb chaws.
Cov lus ceeb toom Clomifene
Contraindicated nyob rau hauv qhov chaw mos los ntshav, uterine fibroids, zes qe menyuam hlwv, lub siab ua hauj lwm puas, puas siab puas ntsws kev nyuaj siab, thrombophlebitis, thiab lwm yam., yog contraindicated.
1. Tsiaj thwmsim muaj cov teebmeem teratogenic thiab fetal toxicity. Thaum lub sij hawm noj tshuaj, ntsuas lub cev kub ntawm lub cev txhua hnub los saib xyuas cov neeg mob ovulation thiab conception, thiab cov tshuaj yuav tsum tau nres thaum conception tshwm sim. Yog tias cov poj niam cev xeeb tub noj tshuaj, kuj tseem yuav muaj 5 feem pua ntawm qhov ua rau fetal malformations.
2. Polycystic zes qe menyuam syndrome yuav tsum tau siv nrog ceev faj.
3. Ua raws li kev txiav txim siab hauv qab no raws li xav tau thaum lub sijhawm tshuaj:
1) Ovulation-stimulating hormone thiab luteinizing hormone;
2) Rau cov neeg siv tshuaj ntev ntev, ntsuas cov ntsiab lus ntawm 24-dehydrocholesterol hauv plasma los txiav txim seb cov tshuaj puas cuam tshuam rau kev tsim cov roj cholesterol.
3) Corticosteroid hloov cov protein cov ntsiab lus hauv plasma.
4) Cov ntsiab lus ntawm thyroxine.
5) Kev sib deev hormone khi globulin cov ntsiab lus.
6) Sodium sulfobromophthalein daim siab ua haujlwm kuaj.
7) Thyroxine-binding globulin cov ntsiab lus (tej zaum nce).
4. Thaum lub sij hawm noj tshuaj yuav tsum xyuam xim rau kev kuaj xyuas:
Ntsuas basal lub cev kub txhua hnub, thiab ntsuas cov tshuaj estrogen thiab serum progesterone thaum tsim nyog; Lub siab ua haujlwm yuav tsum tau kuaj xyuas, thiab yuav tsum tau ua cov kev kuaj mob thiab cov tshuaj tua kab mob rau cov neeg uas tau kho ntau tshaj ib xyoos; Yog tias pom kev cuam tshuam tshwm sim thaum siv tshuaj, cov tshuaj yuav tsum tau nres tam sim ntawd, thiab yuav tsum tau ua raws li cov kev kuaj xyuas tsim nyog.
Kev siv Clomiphene
Qhov koob tshuaj clomiphene ib txwm yog 50mg txhua hnub, thiab tsib hnub yog kev kho mob. Yog tias koj tsis ovulate tom qab kev kho mob, koj yuav tsum tau nce koob tshuaj rau 100mg thiab siv sijhawm tsib hnub ntxiv. Yog tias koj tseem tsis tau ovulate, koj yuav tsum tau nce ntxiv rau 150mg. Hnub tim 5, nws muaj peev xwm ovulate.
Txawm li cas los xij, cov poj niam uas muaj poj niam cev xeeb tub thiab cov poj niam tsis muaj kev coj khaub ncaws siv clomiphene txawv. Cov poj niam cev xeeb tub noj clomiphene rau hnub thib tsib ntawm kev coj khaub ncaws, 50mg ib hnub rau tsib hnub sib law liag. Cov poj niam tsis muaj kev coj khaub ncaws tuaj yeem noj clomiphene txhua lub sijhawm, noj 50mg ib hnub, tsis txhob noj tshuaj rau tsib hnub ncaj, thiab feem ntau ovulate tom qab noj tshuaj rau xya hnub.
Hoobkas
1. Los ntawm kev pom cov khoom zoo, Xi'an Sonwu muaj lub Hoobkas los tsim thiab sim txhua batch ntawm cov khoom. Xi'an Sonwu muaj kev tswj xyuas nruj nruj nrog cov cuab yeej tshaj lij los muab cov ntaub ntawv txhawb nqa rau txhua yam khoom. Raws li kev cai lij choj ntawm Xi'an Sonwu, cov kws tshawb fawb txuas ntxiv tshawb fawb thiab tsim cov khoom lag luam kom ntseeg tau tias lawv tsim cov khoom lag luam nrog cov lus qhia siab dua kom tau raws li cov neeg siv khoom xav tau.
2. Hais txog kev pabcuam, Xi'an Sonwu muaj cov kws tshaj lij kev tsim khoom los xaiv cov khoom siv raw thiab tsim cov khoom, cov cuab yeej siv siab tshaj plaws, thiab cov neeg ua haujlwm ua haujlwm zoo los kuaj cov khoom. Cov neeg ua haujlwm nrog kev paub txog kev muag khoom txawv teb chaws los muag cov khoom thiab Xi'an Sonwu muaj cov kab tshwj xeeb rau kev thauj mus los hauv ntau lub teb chaws thiab nrhiav kom tau raws li qhov xav tau ntawm txhua tus neeg siv khoom.
Daim ntawv pov thawj
Pob
Logistics
Xi'an Sonwu, dhau li kev ua kom cov khoom zoo, qhov tseem ceeb tshaj plaws yog pab cov neeg siv khoom kom tau txais cov pob ntawv kom zoo. Yog li ntawd, Xi'an Sonwu tuaj yeem muab txhua tus neeg xa khoom raws li qhov xav tau sib txawv.
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