Ertugliflozin api

Xian Sonwu Biotech Co., Ltd. yog ib qho ntawm cov lag luam tshaj lij thiab cov chaw muag khoom ntawm ertuglifloliflozin api hauv Suav teb. Peb sov siab txais tos Yuo rau kev lag luam wholesale mis eertugliflolozin API Kev muag khoom ntawm peb lub hoobkas. Cov khoom lag luam zoo thiab tus nqi tsim nyog muaj.

Dab tsi yog ertugliflozin

Ertugliflozin apiYog cov tshuaj kho mob ntshav qab ntsev uas yog ib tus tswv cuab ntawm sodium {{}} glucose cotranster 2 inhibitor (SGLT2) chav kawm. Cov neeg mob uas muaj hom 2 Ntshav Qab Zib Mellitus (T2Dm) feem ntau siv rau kev kho mob glycemic, feem ntau ua kev kho zaub mov noj thaum muaj kev tawm dag zog thiab kev tawm dag zog tsis muaj txiaj ntsig. Cov khoom no tau pom zoo los ntawm FDA hauv 2017 thiab muaj nyob rau ntau yam kev kho mob, xws li segluromet® nrog Metformin® nrog Metformin® nrog Steglujan® nrog SitformLiptin. Tsis zoo li cov khoom noj hniav hypoglyolly (xws li sulfonyhlehlielas, yog li nws tseem tuaj yeem ua tau zoo rau cov neeg mob ntshav qab zib uas tsis muaj txiaj ntsig pancreatic muaj nuj nqi. Qhov tshwj xeeb mechanism ua rau nws yog qhov tseem ceeb ntawm cov hypoglycemy txoj kev kho.

Cov khoom lag luam no tau siv los kho cov ntshav qab zib siab los ntawm hom ntshav qab zib hom 2 thaum ua ke nrog kev tawm dag zog thiab ua haujlwm ib ce muaj zog. Nws ua haujlwm nyob rau hauv lub raum tsis txhob qab zib (ntshav qab zib) los ntawm kev nqus. Qib ntshav qab zib ntshav qis dua yog qhov tshwm sim. Cov neeg mob uas muaj hom 1 lossis insulin - yog tsis muaj ntshav qab zib tsis pab los ntawm ertugliflozin. Cov neeg mob uas muaj ntshav qab zib hom 1 yuav tsum txhaj tshuaj insulin.

Daim Ntawv Pov Thawj Kev Ntsuam Xyuas

Qhov twg yuav ertugliflozin

Xi'an Songwu Biotech Co. Ltd. Tau muaj kev nplua nuj nyob hauv kev lag luam thoob ntiaj teb thiab kev noj qab haus huv. Kev ua txhaum rau txoj kev ntseeg-} Raws thiab ua tau zoo ua ntej yog peb lub tuam txhab cov ntsiab cai. Peb tswj cov khoom lag luam nruj me ntsis, uas txhais tau tias kev xaiv pib los ntawm cov khoom siv raw. Dhau li, peb lis txhua yam thiab txo tus nqi rau qhov ntau kawg, tom qab ntawd peb cov neeg siv khoom tuaj yeem tau txais tus nqi {6- cov khoom siv tau zoo. Raws li cov no, cov neeg muas zaub tau muab ntau cov lus qhia zoo rau peb cov khoom. Yog li koj tuaj yeem nrhiav Xi'an Soniach Co. Ltd. Thaum koj xav yuav ertugliflozin hmoov.

Xi'an Soniau tag ua kom paub tseeb ntawm cov khoom lag luam zoo, yog li cov qauv coj tuaj yeem muab tau. Ntawm no yog qhov ntau.

Cov neeg siv khoom 'paub zoo

Dab tsi yog cov tshuab ntawm kev ua ntawm ertugliflozin

Epagliflozin txo qis cov ntshav qab zib los ntawm kev cuam tshuam SGLT2 transporter hauv lub raum. Feem ntau, ob lub raum reaSorge lim los ntawm cov ntshav txhua hnub, nrog rau kwv yees li 90% ntawm SGLT2 protein thiab seem 10% los ntawm SGLT1. Thaum muaj hnub nyoog elegliflozin khi rau SGLT2 thiab inhibits nws cov haujlwm, qab zib tsis tuaj yeem rov ua dua tshiab hauv cov zis, yog li txo cov ntshav ntshav qab zib. Cov txheej txheem no ua rau peb qhov kev mob metabolic tseem ceeb:

1. Txo cov ntshav ntshav ntshav qab zib

2. Txo qhov hnyav: Cov zis tshem tawm ntawm 200 thiab 300 kcal ntawm lub zog txhua hnub, uas ua rau txo qis me ntsis;

3. Txo cov ntshav siab: Vim tias muaj kev tso zis ntau dua (diuresis me), systolic ntshav siab yog qis dua.

Nws yog qhov tsis muaj kuab muaj kuab heev rau SGLT2 (kwv yees li 2000 zaug uas yuav tsum tsis muaj kev nqus plab hnyuv ntxig thiab yog qhov zoo}}}}}}}}.

Dab tsi yog cov tshuaj ertugliflozin siv rau

Ertugliflozin feem ntau siv los kho hom Ntshav Qab Zib Hom 2 (Mellitus), nrog nws cov haujlwm tseem ceeb tau ua kom cov ntshav qis dua qib. Nws zwm rau hom kev ua tshiab ntawm qhov ncauj mob hu ua SGLT2 inhibitor (sosers ntshav qab zib) Qhov no ua rau nws ua tau zoo rau cov neeg mob pancreatic lossis cov tshuaj insulin tiv thaiv, ua kom muaj kev xaiv ntshav qab zib.

Lub ntsiab txheem tseem ceeb ntawm kev ua yog qhov cuam tshuam ntawm SGLT2 transporter nyob rau hauv lub Proximal raum tubrienal. Los ntawm thaiv cov SGLT2, ertugliflozin txwv tsis pub muaj cov glucose los ntawm kev rov ua dua, yog li ua rau nws tau txais kev tawm hauv cov zis. Qhov no "glucose {{{{}} excreting" me ntsis ntawm insulin qab ntshav qab zib thiab yog kev phom sij ntawm kev pheej hmoo ntawm hypoglycemia.

Ntxiv rau nws cov ntshav ntshav qab zib -} cov nyhuv qis dua,Ertugliflozin apialso has some weight- and blood pressure-lowering effects. Vim tias kev tso zis ua rau muaj kev tshem tawm qee cov calories, cov neeg mob feem ntau muaj kev poob phaus me; Ib txhij, cov tshuaj kuj txhawb nqa sodium excretion, yog li cov ntshav qis qis ntawm cov ntshav siab. Cov kev pab ntxiv no yog tau txais txiaj ntsig tshwj xeeb rau cov neeg mob rog lossis cov neeg muaj kubpertension.

Egliflozin feem ntau siv nyob rau hauv cov neeg laus uas muaj hom 2 cov ntshav qab zib uas nws cov ntshav qab zib tsis txaus nyiam kev noj haus thiab kev tawm dag zog. Nws tuaj yeem raug siv los ua kev sib xyaw nrog lwm cov piam thaj av (xws li manformin, DPP-4 inhibitors, lossis insulin) los txhim kho glycemic tswj. Hauv kev tshawb fawb, ua yeeb yam xws li segluromet (eleflozin + metformin) thiab steglujan (eleflozin + sitagliptin) tseem dav siv.

Feem ntau, kev siv ntawm Eleflozin yog los pab tswj cov ntshav qab zib muaj cov kev pab ntshav qab zib, thaum tseem yuav muaj kev pab rau kev noj qab haus huv ntau xws li cov ntshav poob siab thiab txhim kho ntshav siab. Nws muaj cov ntaub ntawv kev nyab xeeb rau kev nyab xeeb, tab sis kev pheej hmoo ntawm cov teeb meem kev mob tso zis, thiab cov zis yuav tsum tau txiav txim siab thaum siv nws.

Dab tsi yog qhov kev ceev faj rau Dapagliflozin

Feem ntau ntawm cov tib neeg ua kom muaj ertugliflozin zoo, thiab nws cov kev mob tshwm sim feem ntau yog kev coj ua. Txawm li cas los xij, tus txheej txheem tshwj xeeb no tseem ua rau qee qhov tsis zoo vim tias nws txo cov ntshav qab zib los ntawm ob lub raum los ntawm kev tawm hws.

I. Cov kev mob tshwm sim ib qho (tshwm sim hauv cov neeg mob feem ntau)

Cov kev tawm tsam no feem ntau yog feem ntau thiab maj mam ua raws li lub cev yoog raws li lub cev:

Kev mob tso zis (tshwj xeeb tshaj tawm cov zis)

Kaj siab ntsws fungal

Polyuria thiab Nquag Tso Tawm

Qhuav qhuav, kiv taub hau, lossis ntshav siab

Poob phaus me me

Ii. Tsis tshua muaj tshwm sim phiv (tshwm sim hauv qee cov neeg mob)

Nqhis dej thiab tsis muaj zog me me

Kev nce ntshav ketone lub cev

Mob ntshav lipids me me (LDL):

Dab tsi yog qhov kev ceev faj rau Dapagliflozin

Thaum siv cov khoom no, cov ntsiab lus hauv qab no yuav tsum tau sau tseg:

1. Kev ntsuam xyuas lub neej: Cov tshuaj feem ntau ua rau ntawm lub raum roj; Yog li ntawd, lub raum muaj nuj nqi (EGFR) yuav tsum raug saib xyuas tsis tu ncua ua ntej thiab thaum siv. Yog tias EGFR <45 ml / min / 1.73m², cov tshuaj tsis pom zoo vim tias qhov kev ua tau zoo yuav raug txo qis thiab kev pheej hmoo yuav muaj kev cuam tshuam loj heev. Saib xyuas lub raum ua haujlwm thiab qib cov ntshav, tshwj xeeb tshaj yog rau cov neeg uas tsis muaj raum muaj nuj nqi lossis cov tshuaj insulin.

2. Kev pheej hmoo ntawm lub cev qhuav dej thiab hypotension: nws muaj cov nyhuv diuretic me me, uas tuaj yeem ua rau cov ntshav kom tsawg. Cov tib neeg laus, cov uas tau noj cov neeg laus, lossis cov ntshav siab muaj mob siab rau kiv taub hau, hypotension, thiab lub cev qhuav dej; Muaj kev co kom haum yog qhov tseem ceeb.

3. Kev tso zis tawm: Ntau cov piam thaj hauv cov zis txhawb nqa cov kab mob thiab cov kab mob kev sib tw, cov mob tso zis. Nrhiav kev kho mob tam sim ntawd yog khaus lossis tso zis mob tshwm sim.

4. Kabmob Ketoacidosis (DKA): txawm tias tsis tshua muaj, SGLT2 inhibitors tuaj yeem ntxias tau "Euglucose Ketoacidosis" txawm tias cov ntshav qab zib tsis siab. Yog tias tsis muaj hmoo, ua tsis taus pa, huab tsis muaj zog, lossis lwm yam kev tsis txaus siab yuav tsum raug xav tias, thiab kev kho mob tam sim ntawd yog qhov tsim nyog.

Cov neeg tshwj xeeb:

Cov tshuaj no tsis pom zoo rau cov poj niam cev xeeb tub lossis cov poj niam pub mis niam mis, raws li kev tshawb fawb tsiaj tau qhia nws yuav muaj kev cuam tshuam rau lub raum loj hlob; Nws yog contraindicated nyob rau hauv cov neeg mob uas muaj ntshav qab zib hom 1, raws li nws muaj feem ntau txoj kev pheej hmoo ntawm cov tshuaj ketoacidosis; Cov neeg laus cov neeg mob yuav tsum muaj qhov quav me me thiab cov tshuaj xyuas kom zoo rau kev sib npaug hauv electrolyte.

Tsev tsim khoom

1. Xi'an Sonwu muaj lub Hoobkas nrog Tshuag txaus. Ib qho ntxiv, Xi'an Sonwu muaj cov chaw ua haujlwm huv thiab huv si nrog cov cuab yeej siv siab heev. Nyob rau hauv lub tuam txhab cov thawj coj kev coj ua, cov neeg tshawb nrhiav txuas ntxiv tsim cov khoom lag luam tshiab kom tau raws li cov neeg siv khoom xav tau.

2. Xi'an Sonwu muaj cov cuab yeej ntsuas siab thiab cov kws tshaj lij kev sim ua haujlwm, txhua yam uas qhia tau tias Xi'an Sonwu lub hom phiaj los muab cov ntaub ntawv raug thiab cov kev pabcuam zoo.

Daim ntawv muaj cai

Lub thawv

Hloov tshiab cov qauv hloov tshiab

Ntxiv rau kev lav cov khoom zoo, lwm yam tseem ceeb tshaj plaws yog cov neeg siv khoom tuaj yeem tau txais cov khoom kom yooj yim. Yog li, Xi'an Sonwu cov khoom siv txhua hom ntawm cov kws qhia ntawv raws li cov kev xav tau sib txawv.

Tuam Txhab Cov Ntaub Ntawv

Xi'an Songwu Biotech Co., Ltd yog cov kws tsim khoom lag luam suav thiab khoom siv. Nws tau tsim tsa hauv xyoo 2012 thiab yog nyob hauv lub hi- Tech Industrial Zone, Xi'an City, xeev, Suav. Nws them txhua qhov kev txhim kho, kev tshawb fawb, thiab kev tsim khoom noj khoom haus ntxiv, cov nroj tsuag, thiab lwm yam khoom xyaw ntawm cov khoom lag luam kho mob. Lub tuam txhab khoom siv tsib hom khoom siv raw khoom: anti {{6} Cov plaub hau ploj, tsis muaj plaub hau, API, cov leeg cov leeg khoom, thiab cov leeg cov khoom tawm. Xi'an Sonwu ua tsaug rau qhov tseeb ntawm kev koom tes zoo yog qhov kev pabcuam zoo tshaj plaws thiab cov txiaj ntsig zoo. Yog li, txais tos koj qhov kev nug.

Thiab yog tias koj xav paub tusErtugliflozin apiNqe, thov hu rau Xi'an Sonwu.

Email:sales@sonwu.com

Cim npe nrov: ertugliflozin API, Tuam Tshoj Tuam Tshoj, Tuam Tshoj chaw tsim khoom, chaw tsim khoom, lag luam, yuav, Zaub, Raw, muab khoom, kev muag khoom