JBSNF-000088

JBSNF 000088 yog dab tsi

JBSNF-000088, feem ntau hu ua 6-methoxy-nicotinamide los yog 6-MNA, yog ib tug tswv cuab ntawm tsev neeg nicotinamide. Nws yog niacin (vitamin B3) derivative uas muaj methoxy pawg (-OCH3) txuas rau lub nplhaib nicotinamide nyob rau hauv thib rau txoj hauj lwm.

Thawj qhov kev siv ntawm 6-methylnicotinamide yog cov kev kho mob pw tsaug zog. Nws ua haujlwm raws li agonist (cov tshuaj ua kom muaj zog) rau melatonin MT2 receptors, uas yog lub hlwb receptors. Los ntawm kev cuam tshuam nrog cov receptors no, 6-MNA tuaj yeem cuam tshuam li cas lub circadian rhythms thiab kev tswj hwm ntawm lub voj voog pw tsaug zog, yog li txhim kho kom muaj nuj nqis thiab pw tsaug zog zoo.

Raws li kev tshawb fawb, nws tej zaum muaj kev pw tsaug zog zoo thiab tuaj yeem siv los kho ntau yam kev pw tsaug zog, nrog rau lub dav hlau lag thiab insomnia. Tsis tas li ntawd, nws tau raug tshawb xyuas rau nws lub peev xwm los txhim kho kev pw tsaug zog, ua kom ntev tag nrho kev pw tsaug zog, thiab txo qis kev tsaug zog nruab hnub.

Xi'an Sonwu lav muab cov khoom zoo tshaj plaws. Yog tias koj txaus siab rau cov khoom no, thov hu rau Xi'an Sonwu.

Qhov Yuav Yuav 6-Methoxynicotinamide

Xi'an Sonwu Biotech Co., Ltd. muaj kev paub nplua nuj hauv kev lag luam thoob ntiaj teb thiab kev lag luam kev noj qab haus huv. Hais txog kev ntseeg raws li kev ntseeg thiab ua ntej yog peb lub tuam txhab txoj cai. Peb nruj me ntsis tswj cov khoom zoo, uas txhais tau tias kev xaiv pib los ntawm raw khoom. Tsis tas li ntawd, peb tuav txhua qhov kev nthuav dav thiab txo tus nqi mus rau qhov siab tshaj plaws, ces peb cov neeg siv khoom tuaj yeem tau txais cov khoom lag luam zoo. Raws li cov no, cov neeg siv khoom tau muab cov lus pom zoo rau peb cov khoom. Yog li nrhiav Xi'an Sonwu Biotech Co. Ltd. thaum koj xav tau cov khoom no.

Xi'an Sonwu tag nrho ua kom cov khoom zoo, yog li cov qauv tuaj yeem muab tau. Ntawm no yog qhov ntau.

Cov neeg siv khoom 'Cov lus pom zoo

Kev Pabcuam OEM

Xi'an Sonwu tsis tsuas yog tuaj yeem muab cov khoom zooJBSNF-000088hmoov, tab sis kuj muab JBSNF 000088 capsules.

Yog li txhua tus neeg siv khoom tuaj yeem kho cov tshuaj ntsiav lawv xav tau. Thiab cov khoom hauv qab no tuaj yeem muab tau.

1. Customized capsules shells (loj, xim, khoom)

2. Customized fwj (loj, xim, khoom, style)

3. Customized ntim (nqus foil ntim, thawv, nruas)

4. Customized daim ntawv lo (xim zaj duab xis, matte zaj duab xis, daim npog qhov muag)

NNMT Inhibitor yog dab tsi

Ib yam khoom hu ua NNMT (nicotinamide N-methyltransferase) inhibitor yog tsim los nres lossis txo cov haujlwm ntawm NNMT enzyme. Ib qho enzyme hu ua NNMT muaj nyob rau hauv cov hlwb thiab koom nrog cov metabolism hauv cov vitamin B3 daim ntawv nicotinamide. Kev ua haujlwm ntawm NNMT tuaj yeem cuam tshuam rau ntau lub cev kev ua haujlwm thiab kev mob nkeeg.

Cov teeb meem metabolic zoo li kev rog rog thiab insulin tsis kam yog ib qho ntawm kev tsom mus rau NNMT inhibition. Kev nthuav qhia NNMT tau txuas ntxiv rau kev ua haujlwm ntawm metabolic thiab rog, raws li kev tshawb fawb. NNMT inhibitors tau pom cov lus cog tseg hauv kev txhim kho cov cim metabolic xws li lub cev hnyav, qabzib homeostasis, thiab lipid metabolism hauv kev tshawb xyuas ua ntej. Cov tshuaj no tuaj yeem pab tswj kev sib npaug ntawm lub zog thiab txo cov metabolism hauv qhov tsis sib xws los ntawm kev thaiv NNMT.

Dab tsi yog Qhov Zoo Ntawm 6-Methoxynicotinamide

Cov kev tshawb fawb tau ua tiav ntawm 6-Methoxynicotinamide (6-MNA) kom pom tias nws muaj peev xwm cuam tshuam rau kev tswj kev pw tsaug zog thiab lwm yam kev ua haujlwm ntawm lub cev. Cov hauv qab no yog ob peb yam cuam tshuam nrog rau 6-MNA:

1. Txoj Cai Pw Tsaug Zog: Ib qho ntawm 6-MNA cov teebmeem tseem ceeb yog nws cuam tshuam txog kev pw tsaug zog li cas. Nws ua haujlwm ua tus agonist ntawm lub hlwb melatonin MT2 receptors, uas pab tswj lub voj voog pw tsaug zog. Raws li kev tshawb fawb, 6-MNA tuaj yeem ua kom ntev tag nrho cov sij hawm pw tsaug zog, txo kev pw tsaug zog latency (lub sij hawm nws yuav siv sij hawm tsaug zog), thiab txhim kho pw tsaug zog zoo. Rau cov neeg uas muaj kev pw tsaug zog tsis zoo lossis muaj cov qauv pw tsaug zog uas cuam tshuam, nws yuav pab tau.

2. Antioxidant Kev Ua Haujlwm: 6-MNA nthuav tawm cov yam ntxwv ntawm antioxidant, uas txhais tau hais tias nws tuaj yeem pab lub cev siv zog los tawm tsam cov dawb radicals txaus ntshai. Dawb radicals yog cov tshuaj reactive heev uas muaj peev xwm ua mob hlwb thiab ua lub luag haujlwm hauv ntau yam kab mob. 6-MNA tej zaum yuav muaj kev tiv thaiv oxidative kev nyuaj siab thiab lwm yam kab mob los ntawm kev tshem tawm cov dawb radicals. Qhov kev ua haujlwm antioxidant no yuav muaj txiaj ntsig zoo rau kev noj qab haus huv thiab kev noj qab haus huv.

3. Muaj peev xwm txo tau qhov mob: Ntau qhov kev tshawb fawb tau pom tias 6-MNA muaj peev xwm tiv thaiv kab mob. Cov lus teb inflammatory tuaj yeem hloov kho los ntawm inhibiting cov synthesis ntawm cov tshuaj pro-inflammatory. Qhov no qhia tau tias 6-MNA tuaj yeem muaj peev xwm kho tau hauv cov kab mob xws li mob caj dab rheumatoid, kab mob plab hnyuv, lossis kab mob neuroinflammatory uas tshwm sim los ntawm kev mob ntev.

4. Cov teebmeem ntawm Neuroprotective: Cov kev tshawb fawb thaum ntxov qhia txog qhov muaj peev xwm hais tias 6-MNA muaj cov txiaj ntsig zoo ntawm neuroprotective. Nws tau raug pom los tiv thaiv cov hlwb neuronal los ntawm neurotoxicity thiab oxidative kev nyuaj siab. Cov txiaj ntsig no txhais tau tias 6-MNA yuav raug tshawb xyuas rau nws txoj haujlwm hauv cov kab mob neurodegenerative zoo li Parkinson's lossis Alzheimer's. Txhawm rau nkag siab txog nws cov txheej txheem meej ntawm kev ua thiab kev kho mob muaj peev xwm hauv neuroprotection, xav tau kev tshawb fawb ntxiv.

6-Methoxynicotinamide Mechanism Of Action

Txawm hais tias qhov tseeb 6-Methoxynicotinamide (6-MNA) hom kev txiav txim tsis tau tsim tag nrho, cov txheej txheem hauv qab no tau muab tso rau hauv qhov pom ntawm kev tshawb fawb tsis ntev los no:

1. Melatonin MT2 Receptor Activation: Ntawm melatonin MT2 receptors nyob rau hauv lub hlwb, 6-MNA yog xav tias muaj cov nyhuv agonistic. Ib qho tshuaj hu ua melatonin yog qhov tseem ceeb rau kev tswj lub voj voog pw tsaug zog. 6-MNA tej zaum yuav muaj kev cuam tshuam rau kev tswj kev pw tsaug zog, xws li kev pw tsaug zog zoo dua thiab pw tsaug zog luv dua, los ntawm kev ua kom MT2 receptors. 6-MNA yuav synchronize thiab txhawb kom pib pw tsaug zog los ntawm kev txuas rau cov receptors.

2. Antioxidant Kev Ua Haujlwm: 6-MNA tau pom muaj peev xwm antioxidant, uas tuaj yeem ua rau muaj kev cuam tshuam ntau yam. Txhawm rau txo qis oxidative kev ntxhov siab, nws tuaj yeem tshem tawm cov dawb radicals thiab cov pa oxygen reactive (ROS) hauv lub cev. Qhov kev ua antioxidant no tuaj yeem pab piav qhia nws cov txiaj ntsig neuroprotective thiab anti-inflammatory zog los ntawm kev tiv thaiv cov hlwb thiab cov ntaub so ntswg los ntawm kev puas tsuaj los ntawm ntau dawb radicals.

6-MNA zoo li muaj cov tshuaj tiv thaiv kab mob, raws li kev tshawb fawb. Nws tuaj yeem tiv thaiv kev sib txuas lossis tso tawm ntawm cytokines thiab chemokines, ob yam tshuaj uas ua rau mob. 6-MNA tuaj yeem pab txo qis qhov mob ntawm ntau yam mob los ntawm kev tswj cov kab mob inflammatory. Nws cov khoom tiv thaiv kab mob 'cov txheej txheem molecular meej yog tam sim no tau kawm.

4. Modulation of Signaling Pathways: Nws tau raug pom tias 6-MNA cuam tshuam ntau txoj hauv kev ntawm cov xov tooj ntawm tes. Piv txwv li, nws tau raug pom los txhawb lub nuca b (NF-B (NF-B) Kev sib txuas lus thiab cov lus pom zoo. 6-MNA tuaj yeem cuam tshuam cov txheej txheem ntawm tes thiab pab txhawb rau nws cov ntaub ntawv cuam tshuam rau kev mob thiab lwm yam txheej txheem physiological los ntawm kev hloov ntau yam kev taw qhia.

Hoobkas ib puag ncig

1. Xi'an Sonwu muaj lub Hoobkas nrog cov khoom lag luam txaus. Tsis tas li ntawd, Xi'an Sonwu muaj chav ua haujlwm huv thiab huv si nrog cov cuab yeej siv siab heev. Raws li lub tuam txhab kev coj noj coj ua, cov kws tshawb fawb txuas ntxiv tsim cov khoom tshiab kom tau raws li cov neeg siv khoom xav tau.

2. Xi'an Sonwu muaj cov cuab yeej ntsuas qib siab thiab cov neeg ua haujlwm kuaj cov kws tshaj lij, txhua yam qhia tau tias Xi'an Sonwu lub hom phiaj muab cov ntaub ntawv raug thiab ua tau zoo thiab kev pabcuam zoo.

Daim ntawv pov thawj

Ntim

Cov ntaub ntawv logistics

Tsuas yog lav cov khoom lag luam, lwm qhov tseem ceeb tshaj plaws yog cov neeg siv khoom tuaj yeem tau txais cov khoom zoo. Yog li, Xi'an Sonwu muab txhua yam kev xa khoom raws li qhov xav tau sib txawv.

Tuam txhab Profile

Xi'an Sonwu Biotech Co., Ltd. Itd yog cov chaw tsim khoom hauv Suav teb thiab cov khoom lag luam. Nws tau tsim nyob rau hauv 2012, thiab nyob rau hauv Hi-Tech industrial Zone Xi'an nroog, Shannxi xeev, Suav teb. Nws them tag nrho cov xim ntawm txoj kev loj hlob, kev tshawb fawb thiab kev tsim khoom noj khoom haus additives, cog extract, APl thiab lwm yam khoom xyaw ntawm cov khoom kho mob. Peb lub tuam txhab muab tsib yam khoom raw khoom: Anti-hair poob Powders, Nootropic, API, Muscle Building products, Cog Extract. Peb ua siab dawb ntseeg tias qhov chaw ntawm kev koom tes zoo yog cov kev pabcuam zoo tshaj plaws thiab zoo. Yog li, txais tos koj qhov kev nug.

Yog koj xav paubJBSNF-000088hmoov nqi, xav tias dawb rau ocntact Xi'an Sonwu.

E-mail:sales@sonwu.com

Cim npe nrov: jbsnf -000088, Tuam Tshoj, lwm tus neeg, manufacturers, hoobkas, lag luam wholesale, yuav, nqe, tej, ntshiab, raw, mov, kev muag khoom