PNC{0}} hmoov

PNC yog dab tsi -27 Ib ntus

PNC{0}} hmoovyog kev kho mob peptide tsom rau cov kab mob uas muaj kab mob, koom nrog kev tshawb fawb ntawm cov tshuaj tiv thaiv cytopathic, tshwj xeeb tshaj yog hauv kev kho mob. PNC-27 yog tsim los ntawm ntau cov amino acids thiab yog cov txheej txheem polypeptide tshwj xeeb nrog kev xaiv muaj zog rau cov kab mob thiab cov tshuaj lom me me rau cov hlwb ib txwm muaj. Nws txoj kev tshawb fawb thiab kev loj hlob tsom mus rau cov tswv yim tshiab rau kev kho mob ntawm cov kab mob cytopathic, tshwj xeeb tshaj yog rau kev kho mob ntawm cov kab mob ntawm tes uas tsis zoo nrog cov kev kho mob ib txwm muaj (xws li kev kho tshuaj khomob thiab xov tooj cua). PNC 27 yog luv peptide synthesized los ntawm tib neeg, txog 27 amino acid residues ntev. Nws cov yam ntxwv ntawm cov qauv ua rau nws tshwj xeeb khi rau thiab lub hom phiaj tshwj xeeb receptors ntawm daim nyias nyias ntawm cov kab mob, tshwj xeeb tshaj yog cov protein p53 ntawm lub xov tooj ntawm tes. p53 yog cytopathic suppressor noob lub luag haujlwm xws li kev tswj hwm lub voj voog ntawm tes, kho DNA thiab apoptosis. Hauv ntau cov kab mob cytopathic, kev hloov pauv hauv cov noob p53 ua rau poob ntawm kev ua haujlwm, cia cov kab mob kom dim ntawm cov cim kev tuag. PNC 27 tshwj xeeb khi rau no mutant daim ntawv ntawm p53 protein thiab, los ntawm kev hloov nws conformation, activates ib tug series ntawm cell tuag txoj kev, thaum kawg ua rau apoptosis (programmed cell tuag) ntawm cov kab mob. Cov qauv tshuaj ntawm PNC 27 zoo ib yam li lub ntuj p53 protein. Txawm li cas los xij, nws qhov tshwj xeeb amino acid ib ntus ua rau nws nkag mus rau hauv cov cell membrane thiab khi rau p53 ntawm qhov chaw ntawm cytopathic hlwb. Los ntawm cov txheej txheem no, PNC 27 txhim kho cov teeb liab tua tus kheej ntawm cov hlwb cytopathic, inhibits lawv txoj kev loj hlob thiab ua rau lawv tuag los ntawm kev ua ncaj qha lossis ua rau lwm txoj hauv kev molecular. Nyob rau hauv ntau yam kev tshawb fawb preclinical, PNC 27 tau ua pov thawj tseem ceeb ntawm kev tiv thaiv kab mob ntawm tes, tshwj xeeb tshaj yog nyob rau hauv kev kho mob ntawm ntau hom kab mob cytopathic, suav nrog tab sis tsis txwv rau cov kab mob ntawm lub mis, kab mob ntsws cytopathic, kab mob plab cytopathic, thiab lwm yam. Cov kev sim tau pom tias. PNC 27 inhibits kev loj hlob ntawm cytopathic hlwb los ntawm kev tsom mus rau p53 protein nyob rau saum npoo ntawm cytopathic. cov hlwb thiab, rau qee qhov, kov yeej cov tshuaj tiv thaiv ntawm cytopathic hlwb uas cov kev kho mob ib txwm tsis tuaj yeem daws tau. Tsis zoo li cov tshuaj siv tshuaj khomob ib txwm siv, PNC-27 yog qhov xaiv tau zoo thiab muaj kev phiv qis dua.

Raws li ib qho ntawm cov khoom nrov tshaj plaws, PNC-27 tau txais ntau cov lus pom zoo thiab cov lus pom zoo los ntawm kev lis kev cai. Dab tsi nyiam cov neeg siv khoom feem ntau yog qhov zoo. Txawm li cas los xij, Xi'an Sonwu muaj tus nqi sib tw heev. Yog tias koj xav paub ntau ntxiv txog nws, tsuas yog hu rau Xi'an Sonwu Biotech Co., Ltd.

Certificate Of Analysis

Yuav PNC qhov twg -27

Xi'an Sonwu Biotech Co. Ltd. muaj kev paub dhau los hauv kev lag luam thoob ntiaj teb thiab kev lag luam kev noj qab haus huv. Kev hais kom muaj kev ntseeg raws li kev ntseeg thiab kev ua tau zoo ua ntej yog Xi'an Sonwu lub hauv paus ntsiab lus. Xi'an Sonwu nruj me ntsis tswj cov khoom zoo, uas txhais tau tias kev xaiv pib los ntawm raw cov ntaub ntawv. Tsis tas li ntawd, Xi'an Sonwu tuav txhua qhov kev nthuav dav thiab txo cov nqi mus rau qhov siab tshaj plaws kom cov neeg siv khoom tuaj yeem tau txais cov khoom lag luam zoo. Raws li qhov no, cov neeg siv khoom tau muab cov lus pom zoo rau cov khoom. Yog li nrhiav Xi'an Sonwu Biotech Co. Ltd. thaum yuav nws.

Xi'an Sonwu thaum kawg ua kom cov khoom zoo yog li cov qauv tuaj yeem muab tau. Ntawm no yog qhov ntau.

Cov neeg siv khoom 'Cov lus pom zoo

PNC yog dab tsi -27 Siv rau

PNC -27 yog peptide hluavtaws uas feem ntau yog siv los kho cov kab mob cytopathic. Nws cov txheej txheem ntawm kev ua haujlwm yog qhov tshwj xeeb, tso siab rau lub hom phiaj ntawm p53 protein nyob rau hauv cytopathic hlwb kom inhibit qhov kev loj hlob ntawm cov kab mob los ntawm inducing cytopathic cell tuag. Cov protein p53 hu ua "tus neeg saib xyuas ntawm lub genome" thiab yog lub luag haujlwm rau kev tswj lub voj voog ntawm tes, kho DNA puas, thiab ua rau apoptosis thaum cov hlwb raug mob hnyav hauv cov hlwb. Txawm li cas los xij, hauv ntau cov kab mob cytopathic, p53 noob tau hloov pauv lossis tsis ua haujlwm, tso cai rau cytopathic hlwb kom dim ntawm txoj kev tuag ib txwm, ua rau muaj kev loj hlob ntawm cov kab mob txuas ntxiv. Cov txheej txheem ntawm kev ua ntawm PNC 27 yog raws li nws lub peev xwm los khi tshwj xeeb rau cov tsis muaj zog lossis hloov pauv p53 proteins. Cov qauv molecular ntawm PNC 27 zoo ib yam li thaj tsam tseem ceeb ntawm p53 protein, uas ua rau nws paub thiab khi rau p53 receptor nyob rau saum npoo ntawm cytopathic hlwb. Los ntawm qhov kev khi no, PNC 27 hloov pauv qhov sib txawv ntawm cov protein p53, yog li ua kom muaj cov kev taw qhia, thaum kawg ua rau kev tua tus kheej ntawm cov hlwb cytopathic. Tsis zoo li cov tshuaj chemotherapy ib txwm muaj, qhov tshwj xeeb zoo ntawm PNC 27 nyob rau hauv nws cov kev xaiv siab thiab tsis tshua muaj kev phiv. Cov tshuaj chemotherapeutic feem ntau tawm tsam tsis yog tsuas yog cytopathic hlwb xwb tab sis kuj cov hlwb ib txwm, ua rau muaj kev phiv loj xws li kev tiv thaiv kab mob, plaub hau poob, xeev siab, thiab lwm yam. PNC27 feem ntau ua rau cov hlwb cytopathic nrog kev hloov pauv, txo kev puas tsuaj rau cov ntaub so ntswg li qub, txo cov kev tsis zoo hauv kev kho mob. Tsis tas li ntawd, PNC 27 kuj qhia tau tias muaj peev xwm kho tau rau qee yam tshuaj tiv thaiv cytopathic hlwb. Ntau lub hlwb cytopathic tiv taus cov kev kho mob ib txwm muaj xws li kws khomob thiab xov tooj cua vim muaj kev hloov pauv hauv cov noob p53. PNC 27 tuaj yeem rov ua kom rov ua qhov kev puas tsuaj rau tus kheej ntawm cytopathic hlwb los ntawm kev rov ua haujlwm ntawm p53 protein, uas muab kev cia siab tshiab rau kev kho cov kab mob cytopathic-resistant.

PNC{0}} hmoovFeem ntau siv nws cov tshuaj tiv thaiv cytopathic los ntawm kev cuam tshuam nrog p53 protein. Cov protein p53 muaj cov haujlwm tseem ceeb hauv cov hlwb ib txwm muaj, suav nrog kev tswj hwm lub voj voog ntawm tes, kho DNA puas, thiab ua rau apoptosis thaum cov hlwb raug mob hnyav. Txawm li cas los xij, hauv ntau lub hlwb cytopathic, p53 protein yog hloov pauv lossis tsis ua haujlwm, uas ua rau nws tsis tuaj yeem ua haujlwm ntawm inhibiting cov kab mob, yog li tso cai rau cytopathic hlwb kom dim txoj kev tuag thiab txhawb kev loj hlob thiab kev sib kis ntawm cov kab mob. Cov txheej txheem ntawm kev ua ntawm PNC 27 yog raws li nws lub peev xwm los tsom thiab khi rau kev hloov pauv lossis tsis ua haujlwm p53 cov proteins. Nws zoo ib yam li thaj tsam tseem ceeb ntawm p53 los ntawm nws cov qauv molecular, uas ua rau nws khi rau p53 receptor nyob rau saum npoo ntawm cytopathic hlwb. Qhov kev khi no ua rau muaj cov tshuaj tiv thaiv molecular, uas thaum kawg ua rau kev tuag ntawm cytopathic hlwb. Tshwj xeeb, kev khi ntawm PNC-27 hloov pauv cov qauv peb-dimensional ntawm p53 protein thiab reactivates nws li ib txwm ua haujlwm, yog li rov ua dua p53-txoj kev sib kho ntawm tes ntawm tes inhibition thiab apoptosis signaling. Piv nrog rau cov tshuaj chemotherapy, PNC 27 muaj qhov zoo. Cov tshuaj kws khomob cov tshuaj tsis yog tsuas yog tua cov kabmob cytopathic xwb tab sis kuj ua rau lub cev puas tsuaj, ua rau muaj kev phiv xws li kev tiv thaiv kab mob, plaub hau poob thiab xeev siab. PNC 27 feem ntau ua haujlwm xaiv ntawm cytopathic hlwb nrog mutated p53, txo kev puas tsuaj rau cov ntaub so ntswg noj qab haus huv, yog li cov kev mob tshwm sim kuj tsawg. Tsis tas li ntawd, PNC 27 kuj muaj peev xwm ua tau zoo rau cytopathic hlwb uas tiv taus cov kev kho mob ib txwm muaj. Ntau lub hlwb cytopathic tau dhau los ua cov tshuaj tiv thaiv zoo li kev kho mob xws li tshuaj tua kab mob thiab xov tooj cua vim yog p53 hloov pauv lossis tshem tawm.

PNC -27 muaj kev thov dav dav, tshwj xeeb tshaj yog nyob rau hauv kev kho mob ntawm cov kab mob cytopathic txuam nrog p53 noob hloov. p53 yog ib qho tseem ceeb tshaj plaws cytopathic cell inhibitory noob hauv tib neeg lub cev. Hauv ntau cov kab mob cytopathic, p53 proteins hloov pauv lossis ua rau tsis muaj zog, ua rau cov hlwb tsis muaj peev xwm kho tus kheej thiab apoptosis, yog li txhawb kev loj hlob ntawm cytopathic hlwb. PNC 27 muab lub tswv yim kho tshiab rau kev kho cov kab mob cytopathic los ntawm kev rov ua haujlwm ntawm p53 thiab rov ua kom nws cov nyhuv los tiv thaiv cytopathic. PNC 27 feem ntau yog siv los kho cov kab mob ntawm tes nrog p53 hloov pauv lossis tsis ua haujlwm, suav nrog tab sis tsis txwv rau cov kab mob ntsws cytopathic, kab mob ntawm lub mis, kab mob plab cytopathic, kab mob siab cytopathic thiab cov kab mob hauv plab cytopathic. Cov kab mob cytopathic no feem ntau ua rau cov tshuaj tua kab mob thiab tshuaj tua hluav taws xob, ua rau muaj kev kho mob tsawg. PNC{10}} xaiv induces cytopathic cell tuag los ntawm lub hom phiaj ntawm mutant p53 protein nyob rau ntawm qhov chaw ntawm lub hlwb, txo kev puas tsuaj rau cov nqaij mos noj qab haus huv. Tsis tas li ntawd, PNC 27 kuj tau pom tias muaj peev xwm kov yeej cov kev kho mob ib txwm muaj. Tom qab ntau qhov kev kho mob, ntau tus neeg mob cytopathic tuaj yeem tsim cov tshuaj tiv thaiv vim qhov poob ntawm p53 muaj nuj nqi.

Hoobkas ib puag ncig

Xi'an Sonwu ntau lawm Hoobkas yog zoo-tsim, huv si, thiab huv si, nrog txaus Tshuag. Raws li kev coj noj coj ua ntawm lub tuam txhab, cov kws tshawb fawb tau hais kom tsim cov khoom tshiab. Cov hauv qab no yog qhov chaw sim ntawm lub chaw soj nstuam, cov cuab yeej ntsuas qib siab, thiab cov kws tshaj lij kev sim, nrog tus cwj pwm nruj los muab cov ntaub ntawv tseem ceeb rau cov khoom thiab muab cov neeg siv khoom zoo.

Daim ntawv pov thawj

Ntim

Cov ntaub ntawv logistics

Ntxiv rau kev lees paub cov khoom zoo, lwm qhov tseem ceeb tshaj plaws yog cov neeg tuaj yeem tau txais cov khoom lag luam zoo. Yog li, Xi'an Sonwu muab txhua yam kev xa khoom raws li kev xav tau sib txawv.

FAQ

1. Koj hu rau Xi'an Sonwu Biotech Co., Ltd. li cas?

Koj tuaj yeem tiv tauj kuv ntawm email, xov tooj, lossis social media.

2. Koj ua li cas kom paub meej qhov zoo ntawm cov khoom?

Xi'an Sonwu kuaj txhua batch kom Xi'an Sonwu tuaj yeem muab COA rau cov neeg siv khoom. Dhau li ntawm, cov khoom dhau qhov kev xeem rau HPLC, UV, GC, TLC, thiab lwm yam. Xi'an Sonwu kuj koom tes nrog peb tog, xws li SGS.

3. Yuav ntim thiab khaws cia li cas?

Pob: Lub tshuab nqus tsev ntim cov ntawv ntim & ntim cov khoom xa tawm-qib nruas lossis pob raws li cov neeg siv khoom xav tau.

Cia: Khaws cia rau hauv qhov chaw qhuav thiab txias, thiab tsis txhob muaj lub teeb thiab cua sov.

Yog koj xav yuavPNC{0}} hmoov, thov hu rau Xi'an Sonwu.

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