Dab tsi yog SS-31
SS-31 hmoov, tseem hu ua Elamipril Peptide, sawv cev rau kev sib tawg hauv thaj teb ntawm mitochondrial - Tsom cov hom phiaj. Nws yog tus tshiab mitochondrial - hom phiaj kho tus neeg sawv cev nrog lub zog cytoprotrous. Qhov hluavthatic peptide hluavtaws no tshwj xeeb tau tsim los txhim kho kev noj qab haus huv thiab kev ua haujlwm ntawm lub zog tseem ceeb {} Lub zog tseem ceeb {} Lub zog loj, "ntawm txhua lub cev muaj sia. Nws tuaj yeem pab tawm tsam ntau yam kev puas tsuaj txuas rau oxidative kev ntxhov siab thiab mitochondrial ua los ntawm khaws cov mitochondction thiab nthuav dav hluav taws xob.
Los ntawm cov qauv tshuaj lom neeg thiab cov khoom pom zoo, tus yam ntxwv tseem ceeb ntawm nws yog nws tus nqi them zoo. Qhov kev coj zoo no ua rau muaj kev sib cuam tshuam muaj zog nrog kev sib cuam tshuam ntawm Cellular, suav nrog Mitochondrial membrane, txuas ntxiv txhim kho nws qhov nkag mus hauv Mitochondria. Nws cov qauv tshuaj thiab cov amino acid kev teeb tsa antoribe antioxidant muaj peev xwm ua rau ncaj qha hom oxygen cov hom oxygen (Ros) thiab txo qis ntawm tes kev puas tsuaj.
Los ntawm kev xav txog biological, nws cov kev cuam tshuam txuas deb dhau ntawm cov Ros scavening. Txhim kho Mitochondnrial ruaj khov tuaj yeem txo txoj hauv kev ntawm tes, xws li apoptosis thiab necrosis, ob leeg feem ntau ua los ntawm Mitochondrial kawg. Tus peptide yuav tiv thaiv cov ntaub so ntswg uas xav tau, suav nrog lub plawv, raum, muab cov tshuaj ntsuab, muab cov kab mob sib luag. Yog tias koj txaus siab rau SS-31, thov tsis txhob ua siab deb hu rau Xi'an Soniau.
Dab tsi yog SS-31 ua
Cov khoom no yog qhov me me - molecule peptide tsim thaum pib mithochondrial tiv thaiv. Raws li kev tshawb fawb, EramIPretide muaj kev tiv thaiv cuam tshuam rau ntau txoj kev ntxhov siab, xws li cov kab mob ntshav qab zib, neurodegenerative cov kab mob Parkinson thiab Alzheimer, thiab kab mob plawv. Nws tuaj yeem txhim kho cov metabolism hauv lub zog, txo qhov mob, thiab muaj cov teebmeem tseem ceeb neurrotecive cuam tshuam.
Nws lub peev xwm ua tau zoo nyob rau hauv daim cardioprotection, txo qis zuj zus ntawm nurodegenerative tsis sib haum xeeb, thiab teeb meem txuas rau ntshav qab zib tau qhia rau cov mob ntshav qab zib tau qhia hauv cov chaw kuaj mob. Nws yog qhov kev xaiv tau rau kev kho mob ntawm ob peb yam mob vim nws mitochondrial cov kev sib tw thiab muaj zog biocompatibility.
Dab tsi yog cov tshuab ntawm kev ua ntawm SS-31
Nws ua zoo li "bodyguard" rau mitochondria, tiv thaiv thiab kho lub zog sab hauv uas ua rau kev laus thiab kab mob. SS-31 lub cim kev sib txawv ntawm Cardiolipin thiab Sab Hauv Mitochdial Membrane lossis cov tshuaj tiv thaiv kab mob cellular thiab txo cov ntaub so ntswg.
Nws cov tshuab ntawm kev ua yog raws li hauv qab no:
Tub ntxhais mechanism:
Lub hom phiaj: ss -} 31 yog mitochhodial-tsom rau Cardiolipe rau cov Cardiolipip, ib qho tshwj xeeb phospholipipid pom yuav luag txhua tus Mitochondyrial membrane.
Action: This product stabilizes and protects the mitochondrial membrane by binding to cardiolipin, helping to maintain the structure and function of mitochondrial cristae (the energy-generating folds within mitochondria). Thawj cov txheej txheem ntawm kev ua:
Nce Zog (ATP) Ntau Lawm
Txo oxidative kev puas tsuaj
Txhim kho cov ciaj sia ntawm tes
Txhim kho tag nrho cov mitochondrial thiab nqaij muaj nuj nqi
Tshwj xeeb, nws yog raws li hauv qab no:
1. Xaiv mitochondrial uptake
- Nws yog xaiv tau los ntawm Mitochondria thiab cov leeg, raum, {}}}}}}} kev sib cuam tshuam nrog Cardiolipin
Ob qho yog qhov tseem ceeb rau kev ua haujlwm ib txwm muaj ntawm ntau cov enzymes hauv mitochondria thiab qhov xwm txheej thauj cov saw (thiab lwm yam).
Cov khoom no khi rau Cardiolipin, tiv thaiv nws los ntawm Peroxidation (oxidative kev puas tsuaj).
2. Txhim Kho Ntawm Cov Khoom Siv Hluav Taws Xob Hluav Taws Xob
Cov tshuaj no tau nce ntau tiam ntawm ATP (lub zog), muaj kev phom sij ntawm cov hluav taws xob hauv hluav taws xob thiab cov tshuaj uas muaj cov pa roj hmab (Ros).
3. Txo cov pa roj oxygen) (Ros) thiab oxidative ntxhov siab
Tsawg dua hluav taws xob tsis siv txhais tau tias tsawg dua Ros ntau lawm.
Cov khoom no tshem tawm cov teebmeem ntawm cov dawb radicals ntawm cellular qauv raws li oxidative kev ntxhov siab hauv mitochondria.
4. Thaiv Cytochrome C tso tawm thiab Cell Tuag
Cardiolipin oxidation thiab membrane dysfunction ua rau tso tawm ntawm Cytochrome C, uas taw qhia cell tuag. Nws pab txhawm rau txhawm rau txhawm rau qhov kev siv apoptotic no.
Dab tsi yog cov txiaj ntsig ntawm SS-31
Ss -}} 31 muab ntau cov txiaj ntsig los ntawm kev txhim kho mitochondrial muaj nuj nqi, suav nrog kev noj qab haus huv cov kev noj qab haus huv, neuroprotection, thiab los tiv thaiv kev laus.
Cov hauv qab no yog qee qhov txiaj ntsig tshwj xeeb
1. Txhim kho mitochondrial ua haujlwm.Nws cov hom phiaj sab hauv Mitochondrial membrane, txhim kho ATP kev tsim khoom thiab txo cov kev ntxhov siab oxidative.
2. Mob plawv kev noj qab haus huv.Nws yuav tiv thaiv lub plawv tsis ua haujlwm thiab ischemia- reperfusion raug mob.
3. Neuroproction.Qhov khoom siv dag zog muaj lub peev xwm tiv thaiv kev puas tsuaj neurological hauv cov kab mob zoo li Alzheimer raug mob.
4. Anti {{-}} Age Axidention.by txo mitochonding}}}}}}}}}}}}}}}}} yuav pab tua cov hnub nyoog ntsig txog kev laus.
5. Txo cov pa thiab oxidative kev ntseeg siab.Qhov kev ua haujlwm peptide yuav txo qis qhov kev ntxhov siab ntawm oxidative thiab mob hauv ntau txoj kev mob nkeeg.
6. Tiv thaiv tus kab mob raum.Nws tau pom muaj kev tiv thaiv nyob rau hauv ntau lub raum kab mob, suav nrog cov raug mob uas raug mob thiab mob ntshav qab zib nephropathy.
7.
Yog tias koj txaus siab rau tus nqi ntawm SS-31 hmoov lossis muaj lwm cov lus nug txog cov khoom, thov tsis txhob ua siab deb hu rau Xi'an Sonwu.
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