Dab tsi yog flurbiprofen
Flurbiprofen hmoovyog cov tshuaj nonsteroidal anti-inflammatory siv tsuas yog siv los txo qhov mob thiab txo qhov mob. Nws belongs rau phenyl propionic acid chav kawm ntawm NSAIDs uas yooj yim rau qhov mob thiab mob los ntawm kev txo qis cov tshuaj uas muaj feem xyuam nrog kev mob. Nws yog qhov tsim nyog rau kev kho mob rheumatoid mob caj dab, osteoarthritis, ankylosing spondylitis, thiab lwm yam. Nws kuj tseem siv tau rau kev kho mob ntawm cov nqaij mos cov kab mob xws li sprains thiab strains thiab mob me thiab mob xws li dysmenorrhea, postoperative mob, thiab toothache. Nws yog nyob rau hauv chav kawm propionate ntawm NSAIDs thiab muaj cov teebmeem zoo sib xws rau lwm cov NSAIDs, xws li tshuaj aspirin thiab ibuprofen. Flurbiprofen exerts nws qhov kev txiav txim los ntawm inhibiting cyclooxygenase (COX), yog li txo cov synthesis ntawm prostaglandins. Cov prostaglandins yog cov khoom tsim tawm hauv lub cev uas tuaj yeem ua rau mob thiab mob. Anti-inflammatory hmoov flurbiprofen yog ntau thiab ntau siv dav hauv lub neej txhua hnub. Yog tias koj xav tau raw flurbiprofen, tsis txhob yig tiv tauj Xi'an Sonwu.
Dab tsi yog flurbiprofen siv rau
Ntshiab flurbiprofen yog ib yam tshuaj uas tsis yog steroidal anti-inflammatory tshuaj uas txo qhov mob thiab txo qhov kub taub hau thiab mob. Nws qhov kev txiav txim txo qhov mob thiab mob los ntawm inhibiting kev tsim ntawm prostaglandins, tshwj xeeb tshaj yog COX-2. COX-2 yog ib chav kawm ntawm enzymes synthesizing prostaglandins, feem ntau hauv cov ntaub so ntswg puas thiab o. Nws yog ib qho tseem ceeb molecule nyob rau hauv lub inflammatory teb, regulating mob, o, tshav kub, thiab puas cov ntaub so ntswg. Thaum lub sijhawm cov txheej txheem no, prostaglandins tsim los ntawm COX-2 induce vasodilation, platelet aggregation, inflammatory mediators tso tawm, thiab kev hloov kho neurotransmission.
Lub hom phiaj ntawm Flurbiprofen yog COX-2, thiab nws tuaj yeem txo qhov mob thiab mob los ntawm inhibiting kev ua ntawm COX-2. Txawm li cas los xij, nws yuav tsum raug sau tseg tias COX-1 kuj yog ib qho enzyme koom nrog hauv kev tsim cov prostaglandins. Txawm li cas los xij, nws tseem ua lub luag haujlwm tseem ceeb hauv kev tiv thaiv lub cev ib txwm muaj, xws li txhawb kev loj hlob ntawm lub plab mucosa thiab tswj lub raum ua haujlwm. COX yog ib qho tseem ceeb enzyme uas ua lub luag haujlwm tseem ceeb hauv cov tshuaj tiv thaiv kab mob, thiab nws cov catalysis tuaj yeem hloov arachidonic acid (AA) mus rau hauv cov tshuaj lom neeg lom neeg. Ntawm lawv, prostaglandin yog tus neeg nruab nrab tseem ceeb hauv cov lus teb inflammatory, yog li qhov inhibition ntawm COX tuaj yeem ua lub luag haujlwm tiv thaiv kev mob thiab ua kom mob.
Ntxiv nrog rau COX-2 inhibition, flurbiprofen kuj muaj qee yam tshuaj siv tshuaj. Piv txwv li, nws tuaj yeem cuam tshuam kev ua haujlwm ntawm eosinophils thiab txo cov infiltration thiab excretion ntawm inflammatory hlwb. Tsis tas li ntawd, flurbiprofen tuaj yeem tiv thaiv thrombosis los ntawm inhibiting platelet aggregation. Txawm hais tias cov tshuaj antithrombotic nyhuv yog qhov tsis muaj zog, flurbiprofen tuaj yeem txo cov teeb meem thrombotic hauv qee qhov tshwj xeeb, xws li tom qab hloov lub plawv valve thiab phais mob aneurysm.
Cov lus qhia
1. (1) Kev tiv thaiv ntawm aphakic cystic punctate edema tom qab tshem tawm lub lens hauv ophthalmic phais.
(2) Kev kho mob ntawm qhov anterior ntu ntawm lub qhov muag tom qab cataract thiab trabeculoplasty argon laser phais.
(3) Inhibition ntawm cov menyuam kawm ntawv constriction thaum phais.
2. Nws yog siv nyob rau hauv kev kho mob rau inhibit miosis thaum lub sij hawm puab lub qhov muag phais thiab postoperative tiv thaiv kab mob. Kev kho mob tom qab laser trabeculoplasty thiab lwm cov ntaub so ntswg anterior. Nws kuj tseem muaj cov txiaj ntsig kho mob loj heev ntawm papillary conjunctivitis, anterior uveitis, thiab cystoid macular edema tshwm sim los ntawm cov lo ntsiab muag.
3. Rau rheumatoid mob caj dab.
Cov tshuaj dab tsi tuaj yeem cuam tshuam rau flurbiprofen
1. Kev sib xyaw ntawm flurbiprofen nrog acenocoumarol, dicoumarol, phenprocoumon, eptifibatide, low-molecular-weight heparin, anisindione, phenindione, warfarin, thiab lwm yam, ua rau muaj kev pheej hmoo los ntshav ntau ntxiv.
2. Ceev faj yuav tsum tau siv thaum flurbiprofen ua ke nrog alendronate sodium, vim ob leeg tuaj yeem ua rau mob plab.
3. Ua ke nrog calcium channel blockers, qhov kev pheej hmoo ntawm kev mob plab hnyuv loj tuaj.
4. Tsiaj qus chamomile tuaj yeem ua rau muaj qhov tshwm sim tsis zoo rau flurbiprofen, tshwj xeeb tshaj yog kev puas tsuaj rau plab hnyuv thiab raum puas tsuaj, vim chamomile qus kuj muaj cov nyhuv inhibiting prostaglandins.
5. Thaum ua ke nrog ketorolac, lub stimulation ntawm lub plab hnyuv siab raum, thiab peptic rwj, plab hnyuv los ntshav, thiab (los yog) perforation yuav tshwm sim nyob rau hauv mob hnyav. Kev siv ua ke yuav tsum raug txwv.
6. Thaum siv ua ke nrog lithium, qhov kev tshem tawm ntawm lithium txo qis, thiab kev pheej hmoo ntawm lithium lom yuav nce.
7. Thaum ua ke nrog methotrexate, qhov kev tshem tawm ntawm methotrexate txo qis, kev pheej hmoo ntawm kev lom neeg nce ntxiv, thiab cov kev cuam tshuam tsis zoo xws li leukopenia, thrombocytopenia, anemia, thiab mob raum puas tsuaj tuaj yeem tshwm sim.
8. Thaum ua ke nrog cyclosporine, toxicity ntawm lub tom kawg nce, thiab cov tshuaj tiv thaiv xws li lub raum ua haujlwm puas, cholestasis, thiab paresthesia tuaj yeem tshwm sim, thiab cov txheej txheem ntawm kev ua haujlwm tseem tsis tau meej.
9. Kev sib xyaw ua ke ntawm levofloxacin, lox ofloxacin, thiab flurbiprofen tuaj yeem ua rau muaj kev pheej hmoo ntawm qaug dab peg. Cov txheej txheem ua tau yog qhov inhibition ntawm GABA, ua rau lub hauv paus paj hlwb excitation.
10. Thaum flurbiprofen tau ua ke nrog cov tshuaj aspirin, cov ntshav hauv cov ntshav ntawm flurbiprofen txo qis li ntawm 50 feem pua, yog li ob qho tib si yuav tsum tsis txhob siv ua ke.
11. Flurbiprofen tuaj yeem cuam tshuam cov metabolism ntawm sulfonylureas thiab ua rau muaj kev pheej hmoo ntawm hypoglycemia.
12. Flurbiprofen tuaj yeem txo cov nyhuv antihypertensive ntawm -adrenoceptor blockers.
13. Vim tias flurbiprofen tuaj yeem txo lub raum prostaglandins ntau lawm thaum ua ke nrog lub voj diuretics thiab thiazide diuretics, diuretics 'diuretic thiab antihypertensive cov teebmeem yuav raug txo.
14. Thaum ua ke nrog cov tshuaj potassium-sparing diuretics, cov nyhuv diuretic yuav raug txo, thiab hyperkalemia lossis toxic rau lub raum puas yuav tshwm sim.
15. Thaum angiotensin-hloov enzyme inhibitors tau ua ke nrog flurbiprofen, cov nyhuv antihypertensive thiab natriuretic ntawm tus qub raug txo.
16. Thaum ua ke nrog cov tshuaj tiv thaiv kab mob, flurbiprofen tuaj yeem ua rau lub raum tsis ua haujlwm, thiab cov txheej txheem ntawm kev ua haujlwm tseem tsis tau meej.
17. Qee cov kev tshawb fawb tau taw qhia tias kev noj cov tshuaj flurbiprofen thiab tom qab ntawd siv acetazolamide flurbiprofen tuaj yeem ua rau acetazolamide cov ntshav plasma protein khi tus nqi, tab sis tsis muaj qhov tseem ceeb ntawm cov ntaub ntawv. Flurbiprofen kuj tseem me ntsis nce qhov ntim ruaj khov ntawm kev faib tawm ntawm acetazolamide (raws li qhov tseem ceeb) tab sis tsis muaj qhov cuam tshuam loj rau kev tshem tawm acetazolamide, ib nrab-lub neej, lossis cheeb tsam hauv qab nkhaus. Flurbiprofen yog, yog li ntawd, muaj kev nyab xeeb dua li cov tshuaj aspirin hauv cov neeg mob tau txais acetazolamide.
FAQ
Thaum siv cov tshuaj no, thov xyuam xim rau cov hauv qab no:
Tsis txhob noj nrog lwm cov NSAIDs, suav nrog cov tshuaj aspirin, kom tsis txhob muaj kev cuam tshuam tshuaj.
Thov tsis txhob siv sijhawm ntev vim tias siv sijhawm ntev tuaj yeem ua rau muaj kev cuam tshuam tsis zoo hauv lub plab zom mov, daim siab, thiab lub raum.
Thov tsis txhob siv nws thaum cev xeeb tub thiab pub niam mis.
Ua ntej noj nws, qhia koj tus kws kho mob txog koj cov tshuaj tsis haum tshuaj, cov tshuaj noj lossis tshuaj tom khw muag khoom uas koj siv, thiab koj cov keeb kwm kho mob.
Yog tias koj xav paub cov chaw tsim khoom flurbiprofen, koj tuaj yeem tiv tauj Xi'an Sonwu.
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