Hydruobenzole hydrochloride hmoovtseem hu ua hydroxazole hydrochloride hmoov. Hydroxazole hydrochloride hmoov yog cov organic compound nrog cov tshuaj formula C14H13ClN2O. Nws yog ib qho tshuaj tiv thaiv kab mob feem ntau siv los kho mob hemorrhagic conjunctivitis. Hydrobenzole, los yog hydrobenzole hydrochloride, yog ib qho tshuaj feem ntau siv hauv hydrochloric acid thiab feem ntau yog siv los kho tus mob hemorrhagic keratoconjunctivitis. Muaj feem xyuam rau mob kis mob hemorrhagic conjunctivitis. Nws yog siv rau kev kis kab mob hemorrhagic conjunctivitis (xws li, qhov muag liab) thiab tuaj yeem siv rau lwm yam kab mob keratitis, conjunctivitis, thiab kab mob sib kis. Daim ntawv thov kev kho mob yog qhov ua tau sai thiab tsis muaj qhov pom tseeb ntawm qhov muag mucosa.
Pharmacological Action
Anti-microRNA virus tshuaj. Nws inhibits human enterovirus, coxsackievirus, poliovirus, thiab "tus kab mob qhov muag liab." Nws tuaj yeem xaiv inhibit microRNA tus kab mob polymerase hauv cov kab mob. Hauv cov ntaub so ntswg kab lis kev cai, 50ug / ml ntawm cov khoom no tuaj yeem tiv thaiv ntau yam kab mob ntawm tib neeg enterovirus, coxsackievirus, thiab poliovirus. Nyob rau hauv cov ntaub so ntswg kab lis kev cai nyob rau hauv Henan thiab Shanghai, cov khoom no (10ug / ml) tuaj yeem tiv thaiv tus kab mob hemorrhagic conjunctivitis (feem ntau hu ua "qhov muag liab") virus (Shanghai-17 strain). Cov kab no yog hydroxybenzyl derivative ntawm benzimidazole, uas tuaj yeem inhibit RNA polymerase hauv cov kab mob, yog li inhibiting RNA synthesis. Nws muaj cov nyhuv inhibitory tseem ceeb ntawm cov kab mob hemorrhagic conjunctivitis.
Pharmacology thiab Toxicology
Cov khoom no tuaj yeem xaiv inhibit microRNA tus kab mob polymerase ntawm cov kab mob. Hauv cov ntaub so ntswg kab lis kev cai, cov khoom no 50ug / ml tuaj yeem tiv thaiv ntau hom kab mob ntawm tib neeg enterovirus, Coxsackie virus, thiab poliovirus; cov khoom no 10ug/ml tuaj yeem tiv thaiv kab mob hemorrhagic tuberculosis thiab keratitis (feem ntau hu ua "qhov muag liab") tus kab mob (Shanghai-17 strain) (tus kab mob microRNA). Cov txheej txheem ntawm kev ua ntawm cov khoom no tawm tsam microRNA kab mob feem ntau ntseeg tau tias yog inhibit RNA polymerase nyob ntawm tus kab mob coding hauv cov kab mob kom cov synthesis ntawm tus kab mob RNA raug thaiv, yog li ua si lub luag haujlwm inhibitory hauv tus kab mob.
Hydruobenzole Hydrochloride yog siv rau dab tsi
Hydruobenzole hydrochloride feem ntau yog siv los txo qhov ntswg thiab qhov muag congestion. Cov kev siv tshwj xeeb yog raws li hauv qab no:
A. Nasal decongestant
Kev siv:
1. Kho qhov ntswg congestion: nquag siv los kho sinusitis, allergic rhinitis, thiab mob khaub thuas-txog qhov ntswg congestion.
2. Kho qhov ntswg qhov ntswg los ntawm constricting cov hlab ntsha nyob rau hauv lub qhov ntswg kab noj hniav, txo o thiab congestion, thiab ua pa kom zoo.
Yuav siv li cas:
Feem ntau siv los ua cov tshuaj tsuag qhov ntswg los yog tee, ib qho kev siv tuaj yeem muab tau txog li 12 teev ntawm kev pab. Nws raug nquahu kom siv ntau tshaj 2-3 zaug hauv ib hnub, thiab nws yuav tsum tsuas yog siv tsis tu ncua rau peb hnub kom tsis txhob muaj kev sib tsoo.
B. Qhov muag decongestant
Kev siv:
1. Kho qhov muag congestion: siv los txo qhov muag liab thiab congestion tshwm sim los ntawm kev ua xua, khaus, los yog qaug zog.
2. Kho qhov muag tsis pom kev: ua kom cov hlab ntsha hauv lub qhov muag tuaj yeem txo qhov muag tsis pom kev thiab liab.
Yuav siv li cas:
Feem ntau yog siv los ua qhov muag tee, 1-2 tee txhua zaus, 2-4 zaug hauv ib hnub, tab sis nws yuav tsum tsis txhob siv ntev kom tsis txhob muaj kev sib tsoo rov qab los yog lwm yam kev cuam tshuam tsis zoo.
Contraindications ntawm Hydroxybenzone
Hydruobenzole hydrochloride feem ntau yog contraindicated nyob rau hauv cov ntaub ntawv hauv qab no:
1. Kev ua xua rau hydruobenzole hydrochloride: Yog tias tus neeg mob muaj kev fab tshuaj rau hydrochloride lossis nws cov khoom xyaw, cov tshuaj no yuav ua rau muaj kev tsis haum tshuaj hnyav, yog li nws yuav tsum zam.
2. Cov kab mob plawv hnyav: Rau cov neeg mob ntshav siab, kab mob plawv, thiab lwm yam, hydrochloride hydrochloride tuaj yeem ua rau vasoconstriction thiab tuaj yeem ua rau mob plawv, yog li nws yuav tsum tau zam.
3. Hyperthyroidism: Vim tias hydruobenzole hydrochloride tuaj yeem ua rau vasoconstriction thiab nce metabolic tus nqi, nws yuav ua rau cov neeg mob hyperthyroidism ua rau hnyav dua, yog li nws yuav tsum tau siv ceev faj lossis zam.
4. Lub qhov muag kaw glaucoma yog ib qho kab mob qhov muag uas muaj qhov nce siab hauv cov hlab ntsha. Hydruobenzole hydrochloride tuaj yeem ua rau cov menyuam kawm ntawv dilation thiab cuam tshuam rau qhov siab ntawm lub paj hlwb, uas tuaj yeem ua rau cov tsos mob ntawm lub kaum sab kaw glaucoma, yog li nws yuav tsum zam.
5. Kev siv cov tshuaj monoamine oxidase inhibitors (MAOI): Thaum lub sij hawm siv MAOI tshuaj tiv thaiv kev nyuaj siab, hydruobenzole hydrochloride yuav tsum tsis txhob siv tib lub sijhawm vim tias kev siv ob qho tib si ua rau muaj kev pheej hmoo siab ntshav siab.
6. Cov menyuam yaus: Kev nyab xeeb thiab kev ua haujlwm ntawm hydrochloride tsis tau txiav txim siab hauv cov menyuam yaus hnub nyoog qis dua 12 xyoos, yog li nws tsis pom zoo rau cov neeg mob hauv pawg hnub nyoog no.
7. Cov poj niam cev xeeb tub thiab lactating poj niam: Kev nyab xeeb ntawm cov poj niam cev xeeb tub los yog lactating tsis tau txiav txim siab tag nrho, yog li nws yuav tsum tau siv raws li tus kws kho mob qhia thiab ntsuas qhov zoo thiab qhov tsis zoo.
Cov saum toj no yog ib qho contraindications ntawm hydruobenzole hydrochloride. Tshwj xeeb tshaj yog rau cov neeg uas muaj teeb meem kev noj qab haus huv, thov nco ntsoov sab laj nrog koj tus kws kho mob lossis kws muag tshuaj ua ntej siv cov tshuaj no.
Yog tias koj xav paub ntau ntxiv txog cov chaw tsim khoom hydruobenzole hydrochloride, koj tuaj yeem tiv tauj Xi'an Sonwu. Nyem rau ntawm email kom tau txais cov tshuaj zoo hydroxazole hydrochloride hmoov.
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