Dab tsi yog Cov Tshuaj Formula rau Tetrahydrocurcumin
Tetrahydrocurcuminoids hmoovyog tsim los ntawm hydrogenating curcumin muab rho tawm los ntawm rhizome ntawm Ginger cog Curcuma longa, ib txwm tshwm sim muaj txiaj ntsig raw khoom. Tetrahydrocurcumin muaj tsawg dua unsaturated C=C ob daim ntawv cog lus tshaj curcumin nyob rau hauv cov qauv, yog li nws tsis muaj cov conjugated ob daim ntawv cog lus xav tau rau chromophore. Yog li ntawd, nyob rau hauv cov nqe lus ntawm tsos, tetrahydrocurcumin hloov los ntawm lub sib sib zog nqus daj xim ntawm curcumin. Nyob rau hauv lub teeb daj mus rau dawb hmoov. Vim yog qhov tsis txaus C=C ob daim ntawv cog lus, yog tias curcumin khaws cia ntev los yog cua sov thaum lub sij hawm tsim cov khoom tu tawv nqaij, C=C ob daim ntawv cog lus yuav raug oxidized los yog tawg los ntawm kub kub, uas ncaj qha cuam tshuam rau kev ua tau zoo ntawm curcumin.
Tetrahydrocurcumin paub txog nws cov tshuaj tiv thaiv kab mob antioxidant thiab tiv thaiv kab mob thiab feem ntau siv rau hauv kev siv tshuaj thiab tshuaj pleev ib ce. Raws li cov khoom siv tawv nqaij dawb, nws muaj cov haujlwm tseem ceeb hauv inhibiting tyrosinase. Cov nyhuv whitening yog zoo dua li cov paub zoo arbutin. Nws tuaj yeem tshem tawm cov dawb radicals tshiab thiab tiv thaiv kev tsim cov pa oxygen dawb radicals. Nws muaj qhov pom tseeb los tiv thaiv oxidation-oxidation, inhibiting melanin, kho thiab tshem tawm cov pob txha, tiv thaiv kev ua haujlwm, thaiv cov txheej txheem inflammatory, thiab lwm yam. Tsis tas li ntawd, inhibition ntawm dawb radicals, ntau yam inflammatory yam, di ncauj oxygen thiab enzymes, collagenase, thiab hyaluronidase qhia txog qhov muaj peev xwm tiv thaiv kev laus ntawm tetrahydrocurcumin.
Tetrahydrocurcumin pab rau daim tawv nqaij
1. Ua kom dawb
1) inhibit tyrosinase kev ua haujlwm
Tetrahydrocurcumin tuaj yeem txo qhov kev ua haujlwm ntawm tyrosinase intracellular ntawm B16F10 hlwb hauv pawg koob tshuaj ntawm 100 thiab 200 μmol·L -1. Kev ua haujlwm ntawm tyrosinase intracellular txo qis thaum cov hlwb tau muab cov ntsiab lus sib xws ntawm tetrahydrocurcumin (100 thiab 200 μmol·L -1). Cov amino acid enzyme kev ua ub no poob mus rau 84. 51% thiab 83. 38%, feem, thiab qhov sib txawv tau txo qis dua piv nrog cov pab pawg tswj dawb paug.
2) Tiv thaiv ntau pigmentation deposition
Nws tuaj yeem txo qis melanin concentration hauv B16F10 hlwb, tiv thaiv melanin tsim, thiab cuam tshuam kev tsiv teb tsaws thiab kev loj hlob ntawm B16F10 (mos melanoma hlwb). Cov ntsiab lus melanin ntawm cov hlwb txo qis los ntawm 100% mus rau 74. 34%, 80. 14%, 34. 37%, thiab 21. 40%, feem, thaum sib npaug ntawm THC (25, 50, 100, thiab 200 μmol· L -1) tau ntxiv. Qhov sib txawv no yog qhov tseem ceeb tshaj plaws piv rau pawg tswj hwm dawb paug (P ≜ 0. 05 lossis P ≜ 0. 01).
2. Tiv thaiv UV puas
Cov duab ntawm daim tawv nqaij dorsal ntawm KM nas tom qab kaum lub lis piam ntawm kev kho THC thiab UVA irradiation. Cov qhab nia Bissett tau ntsuas ntau pawg nrog sib npaug UVA flux hluav taws xob ntawm kev yees duab. Tus nqi nthuav tawm yog txhais tau tias ± tus qauv sib txawv (N {{0}}/pab pawg). Cov txiaj ntsig tau pom tias kaum lub lis piam tom qab ultraviolet irradiation, daim tawv nqaij tom qab ntawm nas pom pom tseeb tias cov tsos mob ntawm thickening, hardening, wrinkles, thiab scabbing hnyav. Cov tawv nqaij ntawm pawg THC yog qhov muag heev, thiab piv nrog cov pab pawg UV, tsis muaj qhov liab, o, lossis khawb. Tom qab tsib lub lis piam, cov qhab nia ntawm daim tawv nqaij ntawm Bissett tau qis dua hauv THC pawg ntau dua li hauv pawg UV (P <0.01). Cov txiaj ntsig no qhia tau tias THC normalizes photoaging hauv nas thiab muab kev tiv thaiv zoo tiv thaiv UV puas.
3. Antioxidant
1) Scavenge DPPH dawb radicals
Dilute cov tshuaj tetrahydrocurcumin 10, 50, 80, 100, 200, 400, 800, 1600 zaug ua ntu zus kom cov qauv tshuaj thiab 0.1 mmol / L DPPH tov tau sib xyaw ua ke hauv qhov sib piv ntawm 1: 5 thiab react ntawm chav tsev kub. Tom qab 30 feeb, ntsuas tus nqi nqus ntawm 517nm. Kev sim tau ua pov thawj tias tetrahydrocurcumin muaj lub peev xwm tshwj xeeb los tshem tawm DPPH dawb radicals thiab nthuav tawm cov peev xwm antioxidant.
2) Tag nrho cov antioxidant muaj peev xwm
Qhov txo qis peev xwm ntawm tetrahydrocurcumin rau Fe{{0}} nce nrog qhov nce hauv concentration. Thaum cov concentration nce mus txog kaum μmol / L, txo lub zog ntawm tetrahydrocurcumin rau Fe3+ yog ntau dua li cov vitamin C ntawm tib qho kev mloog, thiab qhov sib txawv yog qhov tseem ceeb (P ＜ 0. 05).
4. inhibit tawv nqaij mob
Experimental studies have shown that after 14 consecutive days of continuous observation of wound healing in mice, using THC-SLNs gel, THC and positive control wounds healed faster and with better effects. The descending order is THC-SLNs gel>THC>Qhov zoo sib xws.
Tetrahydrocurcumin yog dab tsi siv rau hauv kev kho tawv nqaij
Tetrahydrocurcumin yog thawj whitening active ingredient nyob rau hauv ntuj turmeric cag extract. Nws tsis tsuas yog muaj zog tshaj plaws tyrosinase inhibitory kev ua si tab sis kuj muaj tshuaj lom neeg ruaj khov zoo heev. Nws kuj zoo nkaus li cov hmoov dawb tsis muaj ntxhiab, yog li kov yeej qhov teeb meem ntawm Ordinary turmeric extract ua tshuaj tsis ruaj khov thiab yooj yim staining ntawm daim tawv nqaij. Ordinary turmeric extract yog daj, tsis muaj tshuaj lom neeg ruaj khov, thiab photosensitive. Nyob rau hauv lub teeb, nws sai sai reacts chemically nrog daim tawv nqaij thiab stains ntawm daim tawv nqaij. Yog li ntawd, xim yog ib qho tseem ceeb qhia los ntsuas cov khoom zoo. Qhov tsaus ntuj ntawm cov xim daj, qhov tsis haum nws yog rau cov khoom siv tawv nqaij. Cov txiaj ntsig zoo tshaj plaws ntawm kev ua kom zoo turmeric extract rau cov tshuaj pleev ib ce yuav tsum yog dawb los yog mis nyuj dawb. High-purity refined turmeric extract tau dhau los ntawm kev ntsuam xyuas kev nyab xeeb, thiab cov txiaj ntsig tau qhia tias nws tuaj yeem muaj kev nyab xeeb thiab ua tau zoo ua nws lub ntuj tsim, ua kom pom kev, thiab ci ntsa iab ntawm tib neeg cov tawv nqaij yam tsis ua rau khaus lossis rhiab heev.
(1) Tetrahydrocurcumin tuaj yeem tiv thaiv kev mob ntawm ntau yam kab mob thiab kev raug mob ntawm daim tawv nqaij thiab tuaj yeem zam qhov mob me me thiab, phais qhov txhab caws pliav, tawv nqaij mob, thiab pob txuv caws pliav.
(2) Tetrahydrocurcumin tuaj yeem kho cov tawv nqaij uas raug puas tsuaj thiab tiv thaiv cov kab zoo, wrinkles, freckles malignant, pigmentation txawv txav, actinic keratosis, psoriasis, thiab nti.
(3) Rov qab los yog txo cov tawv nqaij puas tsuaj los ntawm inhibiting txheej txheem ntawm hnav thiab khaus rau ntawm daim tawv nqaij.
(4) Tetrahydrocurcumin yog tam sim no muaj zog tshaj plaws thiab muaj txiaj ntsig los tiv thaiv kev laus.
(5) Tetrahydrocurcumin, raws li ib qho antioxidant, tuaj yeem ua kom tsis muaj pa dawb radicals.
(6) Tetrahydrocurcumin ua ke nrog lwm cov tshuaj antioxidants, vitamins, thiab minerals tuaj yeem txhim kho cov tawv nqaij zoo nkauj ntawm cov tawv nqaij uas muaj hnub nyoog hormonally.
(7) Curcumin yog absorbed thiab hloov mus rau hauv tetrahydrocurcumin nyob rau hauv lub epithelial hlwb ntawm tib neeg txoj hnyuv. Tetrahydrocurcumin qhia muaj zog antioxidant ntau dua li curcumin.
Tetrahydrocurcumin feem ntau koom nrog lwm cov tshuaj nquag hauv cov khoom tu tawv nqaij, xws li cov vitamins C, E, thiab lwm yam. Nws tuaj yeem siv rau hauv ntau yam khoom, xws li lub qhov ncauj qhov ntswg, tshuaj pleev ib ce, thiab cov khoom tu tawv nqaij.
Yog Tetrahydrocurcumin Safe Rau Cov tawv nqaij
Raws li kev tshawb fawb muaj, Tetrahydrocurcumin dav xav tias tsis muaj txiaj ntsig zoo rau ntawm daim tawv nqaij. Raws li ib tug derivative ntawm curcumin, nws yog siv nyob rau hauv cov khoom tu tawv nqaij los muab antioxidant, anti-inflammatory, thiab whitening pab. Txawm li cas los xij, qee tus neeg yuav muaj kev tsis haum tshuaj lossis cov tawv nqaij rhiab heev, yog li kev ntsuam xyuas ntawm daim tawv nqaij raug pom zoo ua ntej siv cov khoom tu tawv nqaij tshiab.
Tsis tas li ntawd, xav tias koj muaj kev txhawj xeeb ntawm daim tawv nqaij lossis kab mob. Nyob rau hauv tas li ntawd, nws yog ib qhov zoo tshaj plaws mus tham ib tug kws kho mob dermatologist los yog kws kho mob ntawm daim tawv nqaij kom paub meej tias kev siv tetrahydrocurcumin yuav tsis ua rau muaj kev phiv los ntawm tej yam mob. Tetrahydrocurcumin yog ib qho khoom siv tu tawv nqaij uas muaj kev nyab xeeb, tab sis qhov sib txawv ntawm tus kheej thiab cov kev cai tshwj xeeb yuav cuam tshuam rau nws qhov tsim nyog.
Yog tias koj xav paub txog kev ntxuav hniav dawb los yog cov khoom siv tshuaj pleev ib ce, koj tuaj yeem tiv tauj Xi'an Sonwu. Nyem rau email, thiab tom qab ntawd koj tau txais cov ntaub ntawv zoo.
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