Puas yog HBT1 lub siab tsis muaj qhov kawg?
AH, HBT 1 - Ib cov xov xwm txawv txawv uas lub suab zoo li nws tuaj yeem yog lub npe ntawm tus neeg saib xyuas zais ntshis lossis cov txiav Tab sis tsis txhob txhawj, Kuv yuav tsis cia koj tsis paub. Cia peb daws cov kev paub ua ke.
HBT1 yog cov tshuaj ntse me ntsis uas tau piqued qhov kev txaus siab ntawm qee qhov kev tshawb pom ntau dua thiab kev paub ntau lub peev xwm.
Nws tau ua tsis muaj nyob hauv qee cov ces kaum hauv Is Taws Nem, tshwj xeeb tshaj yog cov tho kev fringe hauv pab pawg neeg siv Redropic. Tab sis koj yuav tsum siv HBT1?
HBT1 yog dab tsi?
Hauv thaj teb ntawm kev noj qab haus huv ntawm tes, cov tshawb nrhiav tshiab yog tas li ntawm lub teeb pom kev zoo li cas peb tuaj yeem nkag siab zoo dua thiab txhim kho txoj haujlwm ntawm peb cov hlwb. Ib qho ntawm cov kev tshawb nrhiav no yog YDL223C, tseem hu ua HBT1. Raws li kev tshawb fawb txuas ntxiv, YDL223C tau tawm los ntawm cov tseem ceeb ntawm cellular lub zog kev tsim khoom, mitochondrial muaj nuj nqi, thiab tag nrho cov cellular kev noj qab haus huv cellular. Tab sis dab tsi raws nraim yog YDL223C (HBT1) thiab vim li cas nws thiaj nce tseem ceeb hauv kev saib xyuas kev noj qab haus huv?
Hauv tsab xov xwm no, peb yuav siv sijhawm sib sib zog nqus rau hauv kev tshawb fawb ntawm YDL223C (HBT1)
Nkag siab tias YDL223C: Kev Tiv Thaiv Cellular
YDL223C yog cov gene pom hauv cov poov xab saccharomyces cartchanomyces cerevisiae, tab sis nws muaj nuj nqi thiab cov qauv tau ua dhau los ua kev kawm ntawm tib neeg lub xov tooj ntawm tes. YDL223C Encodes ib cov protein hu ua HBT1, uas yog cov txheej txheem tseem ceeb hauv kev tswj hwm ntau yam, tshwj xeeb yog cov muaj feem cuam tshuam rau mitochondria, lub hwj chim ntawm peb cov hlwb. Txawm hais tias keeb kwm pib hauv cov poov xab nyob rau hauv cov poov xab, nws cuam tshuam rau tib neeg kev noj qab haus huv yog qhov tseem ceeb vim tias ntau lub cellular me ntsis tau txais kev txuag ntawm hom.
HBT1 feem ntau yog koom nrog hauv kev cai ntawm Mitochondrial kev ua si, pab cov cells ua kom muaj zog tsim muaj zog nyob rau hauv daim ntawv ntawm ATP (Adenosine Triphosphate). Qhov no ua rau YDL223C (HDL223C (HBT1) Tus yuam sij hauv kev nkag siab cellular cell, lub zog, thiab lub cev muaj peev xwm tswj cov zog zoo.
Vim li cas YDL223C (HBT1) yog qhov tseem ceeb
Lub luag haujlwm ntawm YDL223C (HBT1) mus dhau kev tsim hluav taws xob. Nws tseem muaj kev koom tes tswj kev ncaj ncees ntawm tes thiab tiv thaiv kev puas tsuaj uas tuaj yeem ua rau muaj kev laus thiab kab mob. Thaum peb lub hlwb ua lub zog, lawv tsim cov khoom noj, xws li cov pa oxygen hom (Ros), uas tuaj yeem ua rau mob oxidative thiab kev ua kom cov kab ke ntawm cov txheej txheem. YDL223C (HBT1) pab tswj hwm cov txheej txheem no, tiv thaiv cov cell los ntawm oxidative kev puas tsuaj thiab ua kom lawv ua haujlwm kom zoo.
Kev tshawb fawb ntawm YDL223C (HBT1) Qhia txog nws txoj haujlwm yuav tau txais txiaj ntsig zoo nyob rau hauv qeeb hauv kev puas tsuaj ntawm tes thiab txhawb nqa kev ua haujlwm ntawm tes.
HBT1 yog tus tshiab ampa receptor txhim kho. Tam sim no, ua ntej koj lub ntsej muag ci, cia peb ua nws pov tseg.
1. Cov receptors yog ib hom ntawm cov khoom noj hauv lub hlwb. Lawv ua ib lub luag haujlwm tseem ceeb hauv Synaptic Kis, uas yog li cas Neuron sib txuas lus nrog txhua lwm.
2.Thaum peb hais tej yam yog Ampa receptor txhim kho, nws txhais tau tias nws txhim kho txoj haujlwm ntawm cov receptors no. Xav txog nws raws li muab lawv me ntsis boost, zoo li kev txhawb nqa pep tham nrog koj lub hlwb hlwb.
3.Qhov no feem txog HBT1 yog tias nws muaj cov kev laus tsis zoo piv rau qee qhov sib txuas. Nws tsis tsim kev tshaj tawm ntawm cov khoom thiab ua rau muaj kev xav tsis tau "Bell-zoo li" thaum nws los tso BDNF (lub hlwb los ntawm cov nruab nrab ntawm lub hlwb). Los ntawm cov kev xav yooj yim dua, nws yuav txhawb BDNF tso tawm yam tsis muaj kev txhaj tshuaj acrobatics.
4.Bdnf yog zoo li fertilizer rau lub hlwb, nws txhawb txoj kev loj hlob thiab txij nkawm ntawm neurons. Yog li txhua yam uas thawb nws hauv txoj kev taw qhia tsim nyog, puas yog? Zoo, uas yog nyob ntawm seb koj siv tau ntev npaum li cas rau, vim tias lawv tsis yog loj hlob zoo li tawm zoo li tawm ntawm ib tsob ntoo.
YDL223C (HBT1) thiab Kev Noj Qab Haus Huv Cellular
Txhawb mitochondrial muaj nuj nqi
Qhov tseem ceeb ntawm YDL223C (HBT1) yog nws lub luag haujlwm hauv Mitochondrial kev noj qab haus huv. Mitochondria yog qhov tseem ceeb rau kev tsim tawm ntawm ATP, uas muab lub zog rau yuav luag txhua yam kev ua haujlwm ntawm tes. Los ntawm kev txhawb nqa Mitochondrial muaj nuj nqi, YDL223C (HBT1) kom muaj zog txaus los ua lub zog txaus los ua kev txhim kho cov txheej txheem tseem ceeb xws li kev loj hlob, thiab kev txhim kho.
Kev noj qab haus huv ntawm koj Mitochondria muaj qhov cuam tshuam ncaj qha rau koj xav li cas thiab koj lub cev ua li cas. Mitochondrial kawg tau txuas ntxiv rau cov teeb meem kev noj qab haus huv, suav nrog kev mob nkees, thiab txawm nrawm nrawm. YDL223C (HBT1) Txhim kho qhov muaj peev xwm ntawm mitochondia rau kev ua kom muaj zog tsim hluav taws xob, uas nyeg txhawb nqa tag nrho thiab kev siv nyiaj ntawm cell tag nrho.
Txo cov oxidative ntxhov siab
Ib qho kev sib tw rau kev noj qab haus huv cellular yog oxidative kev nyuaj siab (uas muaj qhov tsis txaus ntseeg (tsis ruaj khov molecules) thiab lub cev muaj peev xwm neutralize lawv. Sab laug unchecked, kev ntxhov siab oxidative tuaj yeem ua rau kev puas tsuaj rau DNA, cov protein, thiab cov tshuaj mem. Sij hawm dhau mus, qhov no pab txhawb rau kev laus, o, thiab kev txhim kho ntau yam kab mob.
YDL223C (HBT1) Ua si lub luag haujlwm tseem ceeb hauv kev txo cov oxidative kev nyuaj siab los ntawm kev tsim cov khoom siv oxygen hauv mitochondria. Los ntawm kev tswj cov nyiaj tshuav no, nws pab tiv thaiv cov hlwb los ntawm oxidative kev puas tsuaj, txhawb nqa cov hlwb thiab muaj peev xwm qeeb qeeb.
YDL223C (HBT1) yog lub cellular corular sib xyaw uas yog qhov tseem ceeb rau kev noj qab haus huv thiab ntev. Nws lub peev xwm los txhawb mitochondrial muaj nuj nqi, txo cov oxidative kev ntxhov siab, thiab txhim kho cellular zog ntau lawm ua rau kev cuam tshuam tag nrho thiab kev tiv thaiv tawm tsam kev poob qis hnub nyoog. Thaum tshawb nrhiav nws cov peev txheej tag nrho tseem niaj hnub ua haujlwm, HBT1) tau dhau los ntawm kev tshawb fawb hauv kev noj qab haus huv ntawm kev noj qab haus huv ntawm tes.
Txawm hais tias koj tab tom nrhiav kom txhawb cov kev laus zog, lossis tshawb txog cov kev cog lus ntawm tes biology, ydl223C (YBT1) sawv cev rau kev txhawb nqa tshiab ntawm kev kho mob hauv qib cellular.