Geniposide hmoov

Geniposide Ntxiv
Geniposide hmoov, tseem hu ua gardenia thiab geniposidic, yog ib qho iridoid glycoside, ib yam khoom muab rho tawm los ntawm cov txiv hmab txiv ntoo qhuav thiab paub tab ntawm Rubiaceae cog gardenia. Gardenia muaj ntau tshaj 40 physiologically active tshuaj, ntawm cov uas lub active ingredient ntawm gardenia, ib txwm suav tshuaj pom zoo nyob rau hauv tsev thiab txawv teb chaws, yog iridoids. Cov iridoids muaj nyob rau hauv gardenia muaj xws li gardeniposide, geniposidic, hydroxygeniposide, thiab lwm yam. Ntawm lawv, cov khoom xyaw nquag tshaj plaws yog gardeniposide thiab geniposidic. Gardenia glycoside yog ib qho nruab nrab hauv kev tsim tawm ntawm gardenia xiav, gardenia liab, thiab gardenia violet thiab kuj yog ib qho zoo monomer rau cov tshuaj crude.
Cov kev tshawb fawb niaj hnub no qhia tau hais tias nws cuam tshuam rau cov kab mob ntawm lub plab zom mov, kab mob plawv, thiab lub paj hlwb hauv nruab nrab. Tsis tas li ntawd, nws tseem muaj cov tshuaj tiv thaiv tshwj xeeb thiab cov ntaub so ntswg puas tsuaj. Ntxiv nrog rau nws cov kev siv tshuaj, nws kuj tau siv dav hauv lwm qhov chaw. Fermentation nyob rau hauv cov xwm txheej sib txawv tuaj yeem tsim cov khoom noj khoom haus ntuj, geniposidic xiav, thiab Gardenia liab, uas yog siv los kho cov hlab plawv, cerebrovascular, hepatobiliary, thiab lwm yam kab mob, xws li ntshav qab zib. Vim nws muaj peev xwm kho tau zoo, nws tau ua raws li kev mloog hauv cov tshuaj niaj hnub thiab kev tshawb fawb niaj hnub. Nws tau pom cov lus cog tseg hauv ntau yam kev tshawb fawb hauv preclinical rau kev kho mob xws li mob, oxidative kev nyuaj siab, kev paub tsis meej, thiab ntshav qab zib. Yog tias koj tseem xav tau kev cog qoob loo ntawm tus kheej, thov hu rau Xi'an Songwu. Xi'an Songwu tuaj yeem muab koj cov geniposidic ntshiab.

Certificate Of Analysis

Qhov twg yuav Extract Hmoov Geniposide
Xi'an Sonwu Biotech Co. Ltd. muaj ntau tshaj kaum xyoo ntawm kev lag luam kev lag luam tshwj xeeb hauv kev tsim thiab muag cov ntaub ntawv raw. Xi'an Sonwu tau tsim kev sib koom tes ruaj khov thiab txhim khu kev qha nrog cov teb chaws hauv Asmeskas, Asia, Europe, thiab Oceania. Xi'an Sonwu muab cov khoom zoo ua ntej thiab siv zog los muab txhua tus neeg siv khoom nrog cov kev pabcuam zoo kom tau raws li lawv cov kev xav tau tag nrho.
Xi'an Sonwu muab qhov tseem ceeb rau cov khoom lag luam zoo, thiab nws txoj kev cog lus rau kev ua tau zoo yog pom tseeb hauv txhua yam, suav nrog kev xaiv cov khoom siv, kev tsim khoom, kev sim qauv, thiab kev tshaj lij ntawm nws cov neeg ua haujlwm. Los ntawm kev tswj hwm txhua qhov kev nthuav dav, Xi'an Sonwu tuaj yeem txo tus nqi yam tsis muaj kev cuam tshuam zoo, ua kom cov neeg siv khoom tau txais cov khoom muaj txiaj ntsig tshwj xeeb.
Xi'an Sonwu zoo siab rau cov lus pom zoo uas nws tau txais los ntawm cov neeg siv khoom, uas tau lees paub qhov zoo ntawm cov khoom. Txhawm rau ua pov thawj ntxiv cov khoom lag luam ntseeg siab, Xi'an Sonwu zoo siab los muab cov hmoov geniposide cov qauv rau koj kuaj.

Cov neeg siv khoom zoo lus

Dab tsi yog Kev Ua Haujlwm ntawm Geniposide
1. Hypoglycemic thiab lipid-txo cov teebmeem
Geniposide hmoovtuaj yeem txo cov piam thaj hauv cov ntshav thiab txhim kho cov piam thaj hauv cov ntshav qab zib cov nas. Kev kuaj ntshav qabzib tau pom tias geniposidic tuaj yeem txhawb nqa cov piam thaj nqus los ntawm preadipocytes, thiab nws cov nyhuv hypoglycemic hauv vivo thiab hauv vitro yuav cuam tshuam nrog kev ua kom PPARy.

2. Hepatoprotective thiab choleretic teebmeem
Gardenia yog cov khoom tseem ceeb hauv gardenia nrog hepatoprotective thiab choleretic teebmeem. Cov kev tshawb fawb pom tau hais tias kev tswj cov geniposidic los ntawm duodenum ntawm nas tuaj yeem ua rau kom cov kua tsib ntws thiab txo cov roj cholesterol hauv cov kua tsib ntawm nas. Gardeniposide tuaj yeem tiv thaiv daim siab cell puas thiab txo qhov ceev ntawm P450 3Ib tug tiv thaiv kab mob protein nyob rau hauv daim siab microsomes. Cov txheej txheem hepatoprotective ntawm geniposidic tiv thaiv cov kab mob uas tsis yog-alcoholic fatty siab tej zaum yuav muaj feem xyuam rau nws cov tshuaj tiv thaiv oxidation, kev tswj ntawm adipocytokine tso tawm, thiab PPAR qhia.

3. Neurotrophic thiab neuroprotective teebmeem
Geniposide tuaj yeem txo qhov kev qhia ntawm cov kab mob xws li TNF- , IL-1 , thiab ICAM-1 nyob rau hauv lub hlwb ntawm nas nrog cerebral ischemia thiab txo qis ischemia puas rau cranial qab haus huv. Cov kev tshawb fawb tshawb fawb tau pom tias gardenia crude extract nrog gardenia glycoside yog lub ntsiab tivthaiv tuaj yeem txhim kho dementia zoo li tus qauv nas txoj kev kawm thiab kev nco. Cov kev sim tau lees paub tias nws tuaj yeem cuam tshuam qhov kev qhia ntawm HIF-1 thiab HIF-1- nyob ntawm apoptosis-txog gene RTP801 mRNA tshwm sim los ntawm focal cerebral ischemic raug mob, yog li txo qis neuronal apoptosis.

4. Antithrombotic thiab fibrinolytic teebmeem
Kev tshawb fawb ntawm tus qauv bypass ncig thrombosis thiab tus qauv carotid artery thrombosis qauv tau pom tias nws thiab nws cov aglycone tuaj yeem ua rau lub sijhawm ntev coagulation thiab los ntshav thiab txo qhov hnyav ntawm ob lub qauv. Gardeniposide thiab nws cov metabolite tuaj yeem ncua sijhawm ncua sijhawm ntawm femoral artery thrombosis hauv nas thiab inhibit qhov kev ua ntawm phosphatidase.

5. Kev Kho Mob Osteoarthritis
Gardeniposide tuaj yeem txhawb kev loj hlob ntawm ligament fibroblasts, kho cov ntaub so ntswg, thiab kho cov kev raug mob ligament. Tom qab siv nws los cuam tshuam hauv tus qauv luav hauv caug osteoarthritis, nws tau pom tias cov qhab nia histological ntawm tus qauv tsiaj osteoarthritis tau txhim kho. Gardenia yog qhov zoo hauv kev kho mob pob txha thiab contusions, thiab cov kev tshawb fawb tau pom tias nws tuaj yeem txhawb nqa fibroblast proliferation thiab collagen tsim.

6. Anti-inflammatory teebmeem
Cov kev tshawb fawb tau pom tias qhov kev kho mob ntawm gardenia tag nrho glycosides ntawm rheumatoid mob caj dab (RA) muaj feem xyuam rau nws inhibition ntawm inflammatory cytokine kev ua si thiab txo cov provocative mediator ntsiab lus nyob rau hauv inflammatory lesions. Gardenia tag nrho glycosides inhibit NO thiab nitric oxide synthase (NOS). ) qib yog ib qho tseem ceeb ntawm nws txoj kev tiv thaiv RA. Cov kev tshawb fawb tau pom tias gardeniposide tuaj yeem tiv thaiv tib neeg txoj hlab ntsha ntawm cov hlab ntsha endothelial los ntawm kev tsim cov interleukin 6 IL-6 thiab IL-8 induced los ntawm lipopolysaccharide. Cov koob tshuaj nruab nrab thiab siab (15 mg / kg, 30 mg / kg) pawg ntawm gardenia tag nrho cov cycloid tuaj yeem txo cov qib ntawm cell necrosis factor (TNF- ) thiab IL-1 hauv cov ntaub so ntswg ntawm lub paj hlwb nyob ib ncig ntawm hematoma, inhibit The kev qhia ntawm ICAM-1 exerts ib qho inhibitory nyhuv ntawm qhov pib ntawm cov paib saum toj kawg nkaus ntawm cov lus teb inflammatory, thiab muaj kev tiv thaiv kev puas tsuaj rau lub paj hlwb thib ob uas tshwm sim los ntawm inflammatory teb tom qab cerebral hemorrhage.

7. Antioxidant nyhuv
Geniposidic activates glucagon-zoo li peptide-1 receptor (GLP-1R), txhawb kev tsim tawm ntawm intracellular cAMP, ua kom cov dej ntws qis PI3K/Akt-Nrf2 teeb liab txoj hauv kev, thiab ua kom cov haujlwm ntawm heme oxygenase (HO -1) Kev nthuav qhia, tiv thaiv oxidative puas hlwb los ntawm H2O2 thiab ONOO-donor (SIN{10}}). Nws tau pom tias gardeniposide tuaj yeem txhim kho kev txav ntawm lub cev tiv thaiv kab mob oxidative, tshem tawm cov dawb radicals, thiab txhawb kev tsim thiab tso tawm ntawm endogenous NO, yog li tiv thaiv cov hlwb los ntawm oxidative kev nyuaj siab puas.

8. Lub luag haujlwm ntawm lub cev qub
Geniposidic muaj qhov cuam tshuam ncaj qha rau lipopolysaccharide (LPS) hauv vitro thiab qhia tau tias muaj kev sib raug zoo ntawm koob tshuaj zoo; Nyob rau tib lub sijhawm, nws tuaj yeem siv tshuaj-raws li inhibit qhov ua kom ntawm TLR4 thiab TNF hauv RAW264·7 hlwb tshwm sim los ntawm LPS stimulation - Kev qhia ntawm RNA yog downregulated, thiab zus tau tej cov cytokine TNF- yog txo; nws tuaj yeem txo qis LPS qib hauv cov ntshav ntawm LPSemia qauv tsiaj hauv vivo; Nws muaj kev tiv thaiv tseem ceeb rau cov nas uas tau sib tw nrog cov tshuaj tua kab mob ntawm cov cua sov-inactivated Escherichia coli. , nws tau qhia meej tias gardenia glycoside yog cov khoom xyaw nquag ntawm gardenia hauv antagonizing kab mob sepsis.

Hoobkas
1. Xi'an Sonwu Biotech Co., Ltd muaj lub Hoobkas tsim, tsim khoom, thiab khaws cov khoom, yog li nws muaj cov khoom tsim nyog. Xi'an Sonwu muaj kev txiav txim kom zoo, huv si, thiab huv si ntau lawm. Nyob rau hauv Xi'an Sonwu, cov kws tshawb fawb tuaj yeem tsim cov khoom tshiab zoo.
2. Xi'an Sonwu muaj cov cai nruj rau cov neeg ua haujlwm faib los ntawm kev tsim khoom thiab kev sim rau kev muag khoom. Txhawm rau kom ntseeg tau tias txhua yam khoom raug thauj mus los, kev txhawb nqa cov ntaub ntawv nruj thiab kev pabcuam tom qab muag tau muab.

Daim ntawv pov thawj

Pob

Logistics

Dhau li lav cov khoom, lwm qhov tseem ceeb tshaj plaws yog cov neeg siv khoom tuaj yeem tau txais cov khoom zoo. Yog li, Xi'an Sonwu muab txhua yam kev xa khoom raws li kev xav tau sib txawv.

FAQ
Geniposidic yog lub ntuj tsim muaj nyob hauv ntau cov nroj tsuag, suav nrog Gardenia jasminoides. Qee qhov kev mob tshwm sim ntawm geniposidic suav nrog:

Teeb meem plab hnyuv: Qee tus neeg yuav muaj mob plab, xeev siab, lossis raws plab tom qab noj nws.

Lub siab thiab lub raum cuam tshuam: Muaj qee qhov kev txhawj xeeb tias nws tuaj yeem cuam tshuam rau daim siab thiab lub raum ua haujlwm, tshwj xeeb tshaj yog thaum noj tshuaj ntau.

Allergic Reactions: Raws li nrog rau tej yam ntuj tso compound, kev tsis haum tshuaj muaj peev xwm ua tau rau qee tus neeg.

Lwm Yam Kev Phem Tseem Ceeb: Cov kev mob tshwm sim ntxiv tuaj yeem raug txheeb xyuas los ntawm kev tshawb fawb tsis tu ncua thiab cov tshuaj tiv thaiv tus kheej.

Yog tias koj xav paub cov extract hmoov geniposide chaw tsim tshuaj paus, koj tuaj yeem tiv tauj Xi'an Sonwu. Nyem rau email, thiab tom qab ntawd koj tau txais cov khoom zoogeniposide hmoov.
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