Linezolid hmoov

Linezolid piav qhia
Linezolid hmoovyog ib hom kab mob protein synthesis inhibitor tshuaj uas tuaj yeem ua rau muaj kev kho mob tshwj xeeb ntawm ntau yam kab mob kis los ntawm Gram-positive cocci. Nws lub luag haujlwm tseem ceeb yog kev tiv thaiv kab mob thiab ua kom tsis muaj menyuam. Nws tuaj yeem kho cov kab mob ntawm daim tawv nqaij, tawv nqaij, thiab cov ntaub so ntswg mos uas tshwm sim los ntawm vancomycin-resistant enterococci, mob ntsws hauv zej zog, thiab lwm yam. Staphylococcus aureus, Streptococcus, thiab lwm yam kab mob uas tshwm sim los ntawm mob ntsws kuj muaj kev kho mob zoo dua. Nws yog cov tshuaj tua kab mob oxazolidinone hluavtaws, tau pom zoo los ntawm US FDA hauv xyoo 2000, rau kev kho mob ntawm cov kab mob uas tshwm sim los ntawm Gram-positive (G plus ) cocci, suav nrog xav tias lossis paub tseeb tias tsev kho mob tau mob ntsws (HAP), zej zog kis mob ntsws (CAP) , tawv tawv lossis tawv nqaij thiab nqaij mos kab mob (SSTI) thiab vancomycin-resistant enterococcus (VRE) kis los ntawm MRSA.
Linezolid yog cov kab mob protein synthesis inhibitor uas ua rau cov kab mob 50S ribosomal subunit thiab nyob ze rau qhov chaw ua haujlwm. Tsis zoo li lwm yam tshuaj, linezolid tsis cuam tshuam rau kev ua haujlwm ntawm peptidyl transferase tab sis tsuas yog ua rau thawj theem ntawm kev txhais lus, inhibits kev sib txuas ntawm mRNA thiab ribosomes, tiv thaiv kev tsim ntawm 70S kev pib ua haujlwm, thiab yog li inhibits cov kab mob protein synthesis. Qhov chaw thiab hom kev ua ntawm linezolid yog qhov tshwj xeeb. Hauv cov kab mob zoo nrog cov yam ntxwv tseem ceeb lossis tau txais kev tiv thaiv, nws tsis tuaj yeem nkag mus rau kev sib tw nrog lwm cov tshuaj tua kab mob uas inhibit protein synthesis. Nws tsis yooj yim rau induce kab mob tsis kam nyob rau hauv vitro tiam. Tshuaj tua kab mob Zyvox yog thawj cov tshuaj pom zoo hauv Tebchaws Meskas los kho cov kab mob methicillin-resistant Staphylococcus aureus hauv 40 xyoo. Yog li yog tias koj txaus siab rau linezolid thiab xav nrhiav cov ntshiab linezolid, thov hu rau Xi'an Sonwu online.

Certificate Of Analysis

Qhov twg yuav Linezolid
Xi'an Sonwu Biotech Co. ltd yog lub chaw tsim khoom thiab xa khoom nrog kev koom tes nrog kev koom tes nrog Asia, Europe, America, Oceania, thiab lwm lub tebchaws thoob ntiaj teb. Xi'an Sonwu ib txwm ua raws li cov khoom zoo ua ntej; Txhawm rau pab txhua tus neeg siv khoom zoo thiab txaus siab rau txhua tus neeg siv khoom yog kev nrhiav neeg Xi'an Sonwu. Tsis tas li ntawd, Xi'an Sonwu siv zog ua haujlwm zoo hauv txhua qhov kev nthuav dav kom txo cov nqi kom cov neeg siv khoom tau txais cov khoom lag luam zoo. Raws li cov no, cov neeg siv khoom tau muab cov lus pom zoo rau cov khoom. Yog li yog tias koj xav tau cov tshuaj tua kab mob Zyvox, thov hu rau Xi'an Sonwu.
Xi'an Sonwu tag nrho ua kom cov khoom zoo thiab muab cov qauv. Ntawm no yog qhov ntau.

Cov neeg siv khoom 'Cov lus pom zoo

Linezolid Mechanism Ntawm Kev Ua
Linezolid hmoovyog oxazolidinone tshuaj tua kab mob uas ua los ntawm inhibiting kab mob protein synthesis. Lwm chav kawm tshiab ntawm cov tshuaj tua kab mob hluavtaws muaj npe tom qab sulfonamides thiab quinolones. Nws tau nyiam ntau xim rau nws cov txheej txheem tshwj xeeb ntawm kev ua haujlwm thiab kev ua haujlwm zoo los tiv thaiv kab mob. Kev tshawb fawb tau tshwm sim nyob rau hauv xyoo tas los no tau pom tias linezolid muaj cov txiaj ntsig zoo los tiv thaiv mycobacterium tuberculosis (MTB) thiab muaj zog tiv thaiv kab mob tiv thaiv kab mob tiv thaiv kab mob. Linezolid kuj tau ua tiav cov txiaj ntsig zoo hauv kev kho MDR-TB thiab XDR-TB kev kho mob zoo.
Linezolid yog cov kab mob sib xyaw ua ke inhibitor. Lub siab feem ntau metabolizes nws, tab sis CYP450 enzymes tsis metabolize nws, thiab nws tsis yog inducible rau P450 enzymes, thiab nws tsis inhibit qhov kev ua ntawm tib neeg cytochrome isoenzymes. Yog li ntawd, cov tshuaj muaj peev xwm sib cuam tshuam muaj qhov tshwm sim tsawg. Nws lub ntsiab metabolism yog oxidation ntawm lub nplhaib morpholine, uas ua rau ob lub nplhaib tsis muaj zog qhib carboxylic acid metabolites: amino ethoxy acetic acid metabolites thiab hydroxyethyl glycine metabolites. Lub mechanism ntawm kev txiav txim ntawm linezolid tiv thaiv MTB yog khi rau 50S subunit ntawm MTB ribosome, inhibit qhov kev sib txuas ntawm mRNA thiab ribosome, thiab tiv thaiv kev tsim ntawm 70S pib complex, yog li inhibiting kab mob protein synthesis nyob rau hauv thaum ntxov theem ntawm kev txhais lus. Lub hom phiaj ntawm qhov chaw ntawm linezolid yog 23S rRNA, ribosomal L4 thiab L22, Erm-37 methyltransferase, thiab WhiB7 regulatory protein, thiab lwm yam. Vim yog cov yam ntxwv tshwj xeeb ntawm cov tshuaj, tsis muaj kev sib txuam nrog lwm cov protein synthesis inhibitors. .

Dab tsi yog Linezolid siv rau
1. Nosocomial pneumonia: cov kab mob pathogenic yog methicillin-sensitive, methicillin-resistant, lossis Streptococcus pneumonia, nrog rau ntau hom tshuaj tiv thaiv.
2. Community-acquired pneumonia and related bacteremia: community-acquired pneumonia los ntawm Streptococcus pneumonia, nrog rau cov kab mob txuam nrog, los yog zej zog-acquired pneumonia tshwm sim los ntawm methicillin-sensitive hom.
3. Cov kab mob sib kis ntawm daim tawv nqaij thiab cov nqaij mos, nrog rau cov mob ntshav qab zib ko taw yam tsis muaj osteomyelitis: cov tawv nqaij nyuaj thiab cov nqaij mos mos.
4. Cov tawv nqaij tsis sib haum xeeb thiab cov tawv nqaij thiab cov nqaij mos mos: cov tawv nqaij tsis sib haum xeeb thiab cov nqaij mos me me tshwm sim los ntawm Staphylococcus aureus, tsuas yog methicillin-sensitive hom lossis Streptococcus pyogenes.
5. Cov kab mob tshwm sim los ntawm vancomycin-resistant Enterococcus faecium, nrog rau cov kab mob sib kis.

Tshuaj tua kab mob Zyvox muaj cov tshuaj tua kab mob muaj zog tiv thaiv MRSA lossis MSSA thiab MRCNS thiab MSCNS hom coagulase-negative staphylococci. Hauv ib qho kev sim, cov tshuaj tua kab mob ntawm linezolid tawm tsam MRS A thiab MRCNS zoo ib yam li vancomycin, teicoplanin, thiab rifampicin thiab me ntsis siab dua li ntawm teicoplanin tiv thaiv MRCNS, uas yog cov tshuaj tua kab mob yog 76.6 feem pua. Nws cov tshuaj tua kab mob tiv thaiv kab mob MRS ntawm staphylococci yog siab dua li ntawm -lactams, aminoglycosides, thiab fluoroquinolones; Nws kuj yog me ntsis zoo dua los yog zoo ib yam li cov kab mob ntawm cov kab mob ntawm cov tshuaj tua kab mob tiv thaiv kab mob MSS, thiab superior rau Antibacterial kev ua si ntawm erythromycin tiv thaiv staphylococci. Cov tshuaj tua kab mob ntawm linezolid tawm tsam penicillin-sensitive Streptococcus pneumonia thiab penicillin-intermediate Streptococcus pneumonia yog qhov zoo dua li ntawm erythromycin thiab aminoglycoside tshuaj tua kab mob. Linezole muaj cov kab mob bactericidal zoo heev ntawm kev sim tshuaj methicillin-resistant thiab methicillin-sensitive staphylococci, nrog rau cov qauv kab mob ATCC29213.MRSAMSSA thiab Streptococcus pneumoniae ATCC 49619. Thaum txog plaub npaug ntawm MIC, tshwj tsis yog rau MRSA.9 feem pua, tus kab mob mus txog 9 feem pua. {12}} teev; ntawm yim npaug ntawm MIC, tus kab mob bactericidal nce mus rau 99.9 feem pua ​​​​hauv 2-10 teev.

Dab tsi yog Qhov Kev Mob Phem Ntawm Zyvox
Cov xwm txheej tsis zoo tshaj plaws nrog linezolid yog raws plab, mob taub hau, thiab xeev siab. Lwm yam tshwm sim tsis zoo yog ntuav, insomnia, cem quav, ua pob liab vog, kiv taub hau, kub taub hau, qhov ncauj candidiasis, qhov chaw mos candidiasis, fungal kab mob, mob plab, dyspepsia, hloov saj, nplaig discoloration, thiab pruritus.
Tom qab sau npe, cov kev tsis zoo tshwm sim ntawm linezolid suav nrog kev tsim cov pob txha pob txha, mob ntshav qab zib, leukopenia, ntau hom ntshav cell txo thiab thrombocytopenia, peripheral neuropathy thiab optic neuropathy, thiab lactic acidosis. Cov kev tsis zoo no feem ntau tshwm sim hauv cov neeg mob uas tau noj tshuaj ntau dua 28 hnub.

Hoobkas
1. Xi'an Sonwu Biotech Co., Ltd muaj lub Hoobkas los tsim, tsim thiab khaws cov khoom, yog tias koj xav tau, Xi'an Sonwu tuaj yeem xa tuaj rau hauv 24 hnub ua haujlwm. Xi'an Sonwu muaj lub chaw tsim khoom kom zoo thiab huv si. Nyob rau hauv Xi'an Sonwu, cov kws tshawb fawb tuaj yeem tsim cov khoom tshiab zoo.
2. Xi'an Sonwu Biotech Co., Ltd muaj cov kev cai nruj ntawm cov neeg ua haujlwm faib los ntawm kev tsim khoom thiab kev tshawb nrhiav rau kev muag khoom. Escort rau txhua yam khoom, muab cov ntaub ntawv tsis sib haum xeeb thiab kev pab cuam tom qab muag.

Daim ntawv pov thawj

Pob

Logistics

Dhau li lav cov khoom, lwm qhov tseem ceeb tshaj plaws yog cov neeg siv khoom tuaj yeem tau txais cov khoom zoo. Yog li, Xi'an Sonwu muab txhua yam kev xa khoom raws li kev xav tau sib txawv.

FAQ
Cov neeg laus noj 400 mg ntawm qhov ncauj txhua 12 teev los kho cov tawv nqaij lossis tawv nqaij thiab cov nqaij mos, thiab cov tub ntxhais hluas noj 600 mg ntawm qhov ncauj txhua 12 teev. Cov menyuam yaus<5 years old take 10mg/kg orally every 8 hours; 5-11 years old take 10mg/kg orally every 12 hours.
Cov neeg laus uas muaj cov kab mob methicillin-resistant Staphylococcus aureus tau kho nrog linezolid 600 mg txhua 12 teev.
Txhua tus menyuam mos yuav tsum tau txhaj tshuaj ntawm 10mg / kg txhua 8 teev rau xya hnub sib law liag.
Yog tias koj xav paub tus neeg muag khoom linezolid, koj tuaj yeem tiv tauj Xi'an Sonwu. Nyem rau email ces koj tau txais high-zoolinezolid hmoov.
Email: sales@sonwu.com

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