Lub cev yog lub tsheb zoo kawg li. Thaum koj pom koj tus kheej tawm tsam ua pa, dab tsi tshwm sim? Cov khoom no tau tsim los kom kov yeej cov kev sib tw Solubility zoo li mob hawb pob (Coporbations ntawm cov menyuam kab mob ntsws ua rau muaj mob ntsws. Hauv txoj kev tshawb no, peb yuav tsom rau cov txheej txheem ntawm kev ua, cov ntawv thov, thiab ib nrab- lub neej ntawm lub zog tseem ceeb.
Dab tsi yog aminophllo
99 Aminopylline HmoovYog lub siab - Kev Purity Tshuaj feem ntau siv los kho cov pa ua pa, suav nrog tus mob hawb pob, mob ntsws ntev. Nws yog qhov sib txuas lus ntawm theophylline (cov tshuaj nquag) thiab kev ua kom zoo nkauj (uas ua rau theophline ntau dua ntawm cov ntshiab aminophlline, nrog tsawg kawg nkaus impurities. Nws zwm rau hauv methylxanthine chav kawm ntawm cov tshuaj. Nws thawj cov nyhuv yog los so kom txaus thiab dilate cov hlab pa hauv lub ntsws (ua pa ntawm cov leeg kom yooj yim nyob ib puag ncig cov hlab pa. Nws tseem muaj anti me - cov pob txha o, txo qhov ua pa ntawm lub hlwb uas tswj kev ua pa (chaw ua pa). Yog tias koj raug kev txom nyem los ntawm kev ua pa ua pa thiab txaus siab rau Aminophylline, thov tsis txhob ua siab deb hu rau Xi'an Sonwu.
Dab tsi yog aminophline siv rau
Nws yog ib qho tshuaj los kho feem ntau los kho thiab tswj cov pa ua pa, tshwj xeeb yog cov uas muaj kev sib koom tes (BRONCHOSSMASM). Nws cov kev siv thawj zaug yog raws li hauv qab no:
Nws yog cov tshuaj siv kho mob thiab tswj cov pa ua pa, tshwj xeeb yog cov uas muaj kev sib koom tes ua pa (bronchospasm). Nws cov kev siv thawj zaug yog raws li hauv qab no:
1. Hawb pob (mob hnyav)
Hauv tsev kho mob, nws yog siv rau kev tawm tsam hawb pob uas yog kev kho mob hnyav los kho xws li art agorol / salbutamol) thiab corticosteroids. Nws pab dilate txoj hlab pa (bronchi), txhim kho kev ua pa.
2. Cov kab mob huam thaiv cov kab mob pulmonary (mob exacerbents)
Nws kuj tseem siv tau los kho cov qauv loj ntawm Copyrebations (suav nrog mob ntsws thiab embysema) thaum muaj cov tsos mob ua tsis zoo.
3. Tus mob hawb pob lossis mob ntsws coj mus ntaus mob pulmonary
Nws yog feem ntau siv nyob rau hauv cov xwm txheej raug xaiv qhov twg lwm cov kev kho mob yog qhov tsis txaus lossis tsis muaj.
4. APNEA ntawm kev ua ntej
Nws yog siv los tiv thaiv thiab kho apnea (ib qho kev ua pa uas tsis ua pa) nyob rau hauv cov menyuam mos. Nws txhawb txoj kev ua pa ua pa hauv lub hlwb.
Ua li cas Aminophylline ua haujlwm
Cov khoom no feem ntau ua haujlwm los ntawm nws cov khoom siv nquag, theophylline, uas relaxes bronchial du cov leeg thiab txhim kho kev ua pa. Nws yog feem ntau yog siv rau tej yam xwm txheej xws li hawb pob thiab mob ntsws sib ceg (CopD). Nws cov txheej txheem ntawm kev ua yog cov nyom thiab multifaceted, tab sis cov teebmeem tseem ceeb muaj:
1. Phosphodiesterase (PDE) inhibition
Aminopylline inhibits ntau cov enzymes pde, tshwj xeeb yog PDE3 thiab PDE4. PDES feem ntau tsoo cyclice nucleotides, xws li cyclic adenosine monophphate (chaw pw hav zoov) thiab cyclic guanosine monophosphate (CGMP).
Los ntawm kev nyob rau hauv pdes, aminophline nce intracellular qib ntawm camp thiab CGMP. Nce qib ntawm camp / cgmp ua rau kev so ntawm bronchial du cov leeg, ua rau bronchodilation.
2. Adenosine rappefr antagharism
Aminophline block adenosine A1 thiab A2 cov khoom siv, tshwj xeeb yog A2B receptor.
Adenosine tuaj yeem ua rau bronchoconstriction (tshwj xeeb yog nyob rau hauv Asthmatics), tso tawm cov mob uas yog los ntawm Mast Cells, thiab txhim kho kev ua xua. Yog li ntawd, thaiv cov adenosine receptors tuaj yeem tiv thaiv cov teebmeem no, yog li pab dilate cov hlab khaub ncaws thiab txo qhov mob.
3. Txhawb kev tso tawm ntawm endogenous categenous categenous categenous canochas tuaj yeem tso tawm me me ntawm epinephrine (adrenaline) los ntawm adronchodilation.
4. Ob lub chaw pw hav zoov (los ntawm PDE Inhibition) thiab Adenosine Recament artns (piv txwv li cov kev ua si ntawm cov kev ua si ntawm ntau yam) thiab ua kom}-), yog li txo cov pa taws.
5. Diaphragmatic kev txhawb zog tuaj yeem txhim kho kev sib tw ntawm lub diaphragm (cov leeg ua pa ua pa) thiab txo kev qaug zog. Txhim kho cov pa cov leeg ua pa yog qhov tseem ceeb tshwj xeeb rau cov neeg mob uas muaj kev tawm dag zog lossis mob tooj heev.
Dab tsi yog ib nrab - lub neej ntawm aminophylline
Ib nrab - lub neej ntawm nws yog qhov tseem ceeb tib yam li ntawd ntawm theophlline (uas yog cov khoom siv ntsev (uas ua kom muaj zog).
Ib nrab - lub neej ntawm theopylline nws txawv heev thiab yog feem ntau los ntawm cov tib neeg. Nov yog qee qhov tshwj xeeb:
1. Cov neeg raug rau cov neeg laus (tsis - kev haus luam yeeb, txwv tsis pub noj qab haus huv):
Kwv yees li 5 txog 10 teev, nrog ib feem ntawm cov nruab nrab ntawm kwv yees li 8 teev.
2. Qhov tseem ceeb uas cuam tshuam ib nrab - lub neej (uas tuaj yeem ua kom luv lossis ua kom ntev dua):
Cov menyuam yaus (1 {-} 9 xyoo): luv dua ib nrab-lub neej (nruab nrab 3-4 teev).
Cov hluas (10 {- 16 xyoo): ib nrab-lub neej zoo ib yam li cov neeg laus.
Elderly (>60 xyoo, tsis - haus luam yeeb): ntev dua ib nrab {2} lub neej (nruab nrab txog 12 teev lossis ntau dua). Kev haus luam yeeb / haus luam yeeb / tshuaj yeeb dawb siv: Luv luv luv ib nrab ntawm ib nrab - lub neej (tsim lub siab ua kom cov pa siab).
Ib nrab {{0- lub neej nyob rau hauv cov neeg haus luam yeeb tej zaum yuav luv li 3 - 5 teev. Mob siab ua haujlwm: Mob siab tus kab mob (mob siab, kab mob siab, muaj peev xwm ntev dua rau ntawm 24 teev lossis ntau dua).
Lub Plawv Tsis Ua Haujlwm: Tus mob no tuaj yeem nthuav ib nrab ntawm ib nrab - lub neej ntawm cov tshuaj. Kev pham: tej zaum yuav muaj peev xwm me ntsis ntev dua cov tshuaj ib nrab - lub neej. Fever: Tej zaum tau ntev li ib nrab - lub neej.
Noj zaub mov: ib siab -} protein / qis {{{1} {{1} {{{2 {2} lub neej; lub siab -} carbohydrate / qis {{{{{{}} cov zaub mov protein yuav prolong nws.
Vim tias ib nrab - lub neej ntawm aminopylline / theopylline sib txawv tseem ceeb ntawm 3 teev hauv cov neeg mob hluas uas muaj lub siab lossis mob siab. Nws yog qhov tseem ceeb rau kev txiav txim siab txog tus neeg mob lub siab thiab saib cov mob ntshav siab.
Txog kev nug txog 99 aminophline hmoov nqi, paj laum nyob rau Xi'an Soniau, lossis lwm yam khoom {{}}}}} sonwu ncaj qha.
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