Thaum nws los txog kev sib txuas ntawm cov kab mob parasitic kev hem thawj, ob peb txoj kev muab cov spectrum dav ntawm kev kho mob muab los ntawm albendazole, tshwj xeeb tshaj yog nyob rau hauv nws cov ntshiab, 99 daim ntawv. Cov lus qhia no tshawb nrhiav cov khoom ntawm Albendazole, nws siv tawm tsam helthinites thiab nqaij parasites, kev noj qab haus huv tseem ceeb thaum kho, thiab lub sijhawm ua haujlwm zoo.
Dab tsi yog albendazole
99 ALBENAZOLE HmoovHais txog Albendazole nrog kev coj dawb huv ntawm 99% lossis siab dua. Cov khoom no yog cov tshuaj tiv thaiv antiparasitic tshuaj tiv thaiv cov tshuaj feem ntau siv los kho ntau yam kab mob. Cia peb kawm paub ntxiv txog lub anthalmintic no, pib nrog nws lub cev thiab tshuaj lom neeg.
Cov Khoom Siv Lub Cev: Cov khoom no yog feem ntau yog ib qho hmoov dawb dawb. Nws muaj qhov iab iab me ntsis, tsis muaj ntxhiab, thiab yog insoluble hauv dej, ib qho tseem ceeb cuam tshuam rau nws cov qauv thiab kev nqus. Nws yog me ntsis soluble hauv acetone thiab dihloromethane, kev ua insoluble hauv ethanol, thiab insoluble hauv dej, tab sis yooj yim soligle hauv glacial acetic acid.
Tshuaj lom neeg muaj peev xwm: nws cov qauv tseem ceeb muaj cov kev tiv thaiv kev tiv thaiv kev tiv thaiv kab mob Axidation), thiab cov tshuaj uas cuam tshuam nrog cov tshuaj Parlylation (uas cuam tshuam kev ua yeeb yam tshuaj ntsuab (uas cuam tshuam kev ua yeeb yam tshuaj ntsuab (uas cuam tshuam kev ua yeeb yam tshuaj ntsuab (uas cuam tshuam kev ua yeeb yam tshuaj ntsuab (uas cuam tshuam kev ua yeeb yam tshuaj ntsuab (uas cuam tshuam nrog kev sib cais tshuaj thiab kev faib tshuaj Nws yog rhiab rau cov hauv paus ruaj khov (uas tuaj yeem ua rau cov pab pawg tseem ceeb), lub teeb (tshwj xeeb tshaj yog cov teeb pom kev zoo nkauj), thiab muaj qhov kub nyob hauv lub plab zom mov. Yog tias koj txaus siab nyob rau hauv 99% Albendazole, thov koj xav tiv tauj Xi'an Soniau.
Dab tsi yog albendazole siv rau
Albendazole yog qhov dav {-}}}}}}} Cov kev tswj hwm kev noj qab haus huv los tiv thaiv cov av- hy7. Nws muaj npe nyob rau hauv lub ntiaj teb kev noj qab haus huv cov npe ntawm cov tshuaj tseem ceeb. Nws yog feem ntau siv los kho kab mob tshwm sim los ntawm cab (cua nab).
Thawj kab mob pib nws muaj xws li.
1. Neurocysticosis, tshwm sim los ntawm cov kab menyuam (hlwv) ntawm cov nqaij npuas tapworm (Taenia solium) nyob rau hauv lub hlwb, leeg, lossis lwm yam ntaub so ntswg. Nov yog tus mob hnyav heev thiab ua rau kis tau Sphamepy thoob ntiaj teb. Nws yog thawj cov tshuaj siv los tua cov hlwv no.
2. HELDATID DAB TSI (Cystic Echinococcocos), tshwm sim los ntawm cov menyuam dev (Taenia Canis), feem ntau yog cov hlwv (feem ntau hauv lub siab lossis lub ntsws). Nws yog siv ua ntej, thaum lub sijhawm, thiab tom qab kev phais mob lossis kev phais mob hauv Parasites los tua cov cab thiab tiv thaiv kev rov ua dua.
3. Kab mob hnyav rau lub kaus mom hlau (av qeeg (av {{1- pinkinisias). Nws yog ua tau zoo tawm tsam ntau cov kabmob plab hnyuv thiab feem ntau siv hauv cov kev pab cuam loj loj hauv cov cheeb tsam uas yog helminisis mob siab. Nws tuaj yeem kho ASCARIAIS, WAUGJWorms, hookworms, thiab plab hnyuv cab.
4. Lwm yam kab mob
Xws li wookworms thiab cov cab. Cutension Larva Migrans yog qhov kev sib tw tawm los ntawm tsiaj cov tsiaj nyaum tsiaj. Cov neeg mob microstroridiosis (xws li encephalitis) muaj ntau yam hauv kev txhaj tshuaj immunocompomised.
Dab tsi koob albendazole ua
Albendazole ua haujlwm los ntawm kev tshaib plab thiab tuag tes rog lub parasite. Nws ua li no los ntawm kev sib tw tshwj xeeb thiab rhuav tshem cov qauv tseem ceeb hauv lub cab uas tus tswv tsev tsis cia siab rau tib txoj kev. Tus txheej txheem no tuaj yeem faib ua peb kauj ruam tseem ceeb.
1. Hom phiaj - tubulin
Nws yog lub hom phiaj tseem ceeb yog cov protein hu ua - tubulin. Tubulin yog ib feem ntawm microlotubules - ntev, khoob khoob uas ua rau lub cev pob txha pob ntseg (cytoskeleton). Microrotres yog qhov tseem ceeb rau ntau cov txheej txheem ntawm tes.
2. Inhibing microtomine polymerization
Albendazole muaj kev sib txawv heev rau kev sib txawv rau cov cab no - tubulin. Thaum nws khi rau cov protein no, nws tiv thaiv lawv los ntawm kev sib sau ua kom microlotubules. Tus txheej txheem no hu ua catabolism catabolism.
3. Cuam tshuam cov ntsiab lus cellular
Nrog microlotules puas, lub parasite lub hlwb tsis tuaj yeem ua lawv cov haujlwm tseem ceeb. Ob qho kev cuam tshuam tseem ceeb tshaj plaws yog: cov microlotubules tau koom nrog hauv kev thauj cov hnab qab zib (qab zib) los ntawm cov kab mob plab rau hauv nws cov hlwb. Yog tsis muaj microlotubules, cov parasite yuav nqus tsis tau cov as-ham. Qhov no ua rau depletion ntawm cov khw muag khoom siv hluav taws xob (glycogen), thaum kawg ua rau tshaib plab. Cov microlotubules kuj tseem ceeb heev rau kev faib xov tooj ntawm tes (mitosis) thiab tswj cov qauv ntawm cov kab mob plab hnyuv. Kev cuam tshuam ntawm microleubules renders cov cab no immobile (tuag tes tuag taw). Cov kev sib xyaw ua ke ntawm kev tshaib plab thiab tuag tes tuag taw cia lub cev ua kom ib txwm rhuav tshem kev tuag lossis tuag patasites los ntawm lub plab zom mov.
Muaj pes tsawg hnub nws noj rau Albendazole ua haujlwm
Qhov pib ntawm nws cov txiaj ntsig zoo nyob ntawm ntau yam, feem ntau hom cab kab mob raug kho. Cov hauv qab no yog cov xwm txheej tshwj xeeb.
1. Rau cov pob txha caj pas (xws li cov cab ntsuab, cov voj voog)
Txawm hais tias cov cua nab tuag sai sai, xws li tus txiv ntseej - mob plab, raws plab, mob raws plab, mob plab zom mov) lossis ntev ntev mus daws. Qhov no yog vim tias lub cev xav tau lub sijhawm los ntiab cov tuag cov neeg tuag thiab ua pa rau kev tso tseg.
2. Rau cov nqaij so ntswg-} ayas tsis txaus ntseeg (xws li Echinococcos lossis neurocysticercosis lossis neurocysticercosis lossis neurocysticercosis lossis neurocysticercosis)
Cov mob hnyav ntawm hom no xav tau kev kho mob ntev dua, piv txwv li lub hlis rov qab ua raws 14 {-hnub so, rov ua dua rau ob peb hlis). Txawm li cas los xij, kev kho mob kho mob tseem ceeb lossis daws teeb meem / kev daws teeb meem yuav siv sijhawm ntev dua, lub hlis, lossis ntev dua. Thaum lub sijhawm ntev ntev, kev nce qib tuaj yeem raug taug qab los ntawm kev kuaj ntshav thiab kev kho mob (xws li CT lossis MRI scans). Cov tsos mob yuav maj mam txhim kho thaum kho, tab sis daws teeb meem yuav qeeb.
3. Rau lwm cov chav kawm, cov chav kho mob feem ntau yog ntev dua li cov kab mob Helinthy (piv txwv li, 3-7 hnub). Cov tsos mob tuaj yeem txhim kho li ob peb hnub.
Thaum noj tshuaj yuav tshem tawm cov cab no kis tau sai sai, lub cev kev kho kom zoo (cov tsos mob nyem) yuav siv sijhawm ntev dua. Yog li ntawd, cov kws tshaj lij kev noj qab haus huv yuav tsum saib xyuas cov neeg mob tu ncua thoob plaws kev kho.
Yog tias koj xav nyob rau hauv 99 albendazole cov nqe lossis muaj lwm cov lus nug txog cov khoom, thov tsis txhob ua siab deb hu rau Xi'an Sonwu.
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