Coenzyme q10 hmoovyog ib qho ntawm cov khoom koom nrog hauv cov saw hlau thauj hluav taws xob thiab kev ua pa aerobic hauv mitochondria ntawm eukaryotic hlwb. Nws yog xim daj rau txiv kab ntxwv-daj crystalline hmoov, tsw thiab saj tsis qab, thiab yooj yim decomposed thaum raug lub teeb. Coenzyme Q10 yog cov khoom noj muaj roj-soluble, uas tuaj yeem tsis tsuas yog muab lub zog rau lub plawv, tab sis kuj muaj cov haujlwm zoo ntawm kev tiv thaiv oxidation thiab tshem tawm cov pa dawb radicals, thiab tuaj yeem tiv thaiv lipid peroxidation ntawm phab ntsa hlab ntsha, yog li tiv thaiv atherosclerosis. tshwm sim thiab kev loj hlob ntawm sclerosis, thiab coenzyme Q10 nws tus kheej tsis muaj kev phiv tshuaj lom. Nws cov haujlwm tshwj xeeb tuaj yeem cuam tshuam los ntawm kev pab lub plawv los tiv thaiv lub plawv cov leeg zoo, txhim kho cov laus ntawm daim tawv nqaij, tiv thaiv qaug zog, thiab tiv thaiv kab mob.
Vim tias coenzyme Q10 yog cov khoom noj muaj roj-soluble, nws yuav tsum tau noj ua ke nrog cov rog rog kom pab txhawb kev nqus txhua hnub. Yog li ntawd, noj nws nrog zaub mov lossis hauv ib nrab ib teev tom qab noj mov pom zoo. Coenzyme Q10 feem ntau yog noj peb zaug ib hnub twg. Nws yuav yog qhov zoo tshaj rau noj tshais, pluas su, lossis noj hmo lossis hauv ib nrab teev tom qab noj mov kom zoo tshaj plaws.
Dab tsi yog Pharmacological Properties ntawm Coenzyme Q10
Coenzyme Q10 muaj kev ua haujlwm ntawm kev txhawb nqa oxidative phosphorylation cov tshuaj tiv thaiv thiab tiv thaiv kev ncaj ncees ntawm biofilm qauv. Cov khoom no yog cov roj-soluble quinone compound uas muaj dav hauv cov kab mob. Coenzyme Q10 los ntawm ntau qhov chaw muaj cov lej sib txawv ntawm cov kab sib txuas isoamyl. Tib neeg thiab tsiaj txhu muaj kaum isoamyl units, yog li nws hu ua coenzyme Q10. Coenzyme Q10 ua lub luag haujlwm tseem ceeb hauv kev hloov pauv ntawm proton thiab hloov hluav taws xob hauv cov kab ua pa hauv lub cev. Nws yog ib qho activator ntawm tes ua pa thiab cov metabolism thiab ib qho tseem ceeb antioxidant thiab tsis muaj kev tiv thaiv kab mob.
Cov kev sim tsiaj tau lees paub tias cov khoom no feem ntau muaj cov teebmeem hauv qab no:
(1) Nws tuaj yeem txo qhov tsis muaj zog ntawm myocardial contractility thiab cov ntsiab lus ntawm creatine phosphate thiab adenosine triphosphate thaum mob ischemia, tswj cov morphology thiab cov qauv ntawm mitochondria hauv ischemic cardiomyocytes, thiab muaj kev tiv thaiv tshwj xeeb ntawm ischemic myocardium.
(2) Ua kom lub plawv tso zis thiab txo qis peripheral tsis kam, uas yog qhov zoo rau kev kho mob plawv tsis ua hauj lwm thiab tuaj yeem cuam tshuam cov synthesis thiab secretion ntawm aldosterone thiab thaiv nws cov nyhuv ntawm lub raum tubules.
(3) Thaum perfusing lub ventricular leeg ntawm cov tsiaj nyob rau hauv hypoxic tej yam kev mob, lub sij hawm ntawm kev txiav txim muaj peev xwm yuav luv luv, thiab qhov pib ntawm ventricular arrhythmia yog siab dua li cov tsiaj tswj.
(4) Nws tuaj yeem txo cov hlab ntsha peripheral thiab muaj cov nyhuv anti-aldosterone.
(5) Cov khoom no kuj muaj cov nyhuv anti-cardiotoxic ntawm doxorubicin thiab cov nyhuv hepatoprotective.
Coenzyme Q10 tuaj yeem siv los ua kev kho mob ntxiv rau cov kab mob hauv qab no:
1. Cov kab mob plawv, xws li kab mob myocarditis thiab mob plawv tsis txaus.
2. Kab mob siab, xws li kab mob siab viral, subacute daim siab necrosis, thiab mob siab ua haujlwm siab.
3. Kev kho mob qog noj ntshav: Nws tuaj yeem txo qee qhov kev phiv tshwm sim los ntawm kev siv xov tooj cua thiab kws khomob.
Ua ntej noj Coenzyme Q10
Nug koj tus kws kho mob, kws muag tshuaj, lossis lwm tus kws kho mob rau cov lus qhia, thiab qhia rau koj tus kws kho mob paub ua ntej yog tias koj muaj
1. Ntshav siab lossis qis;
2. Tau txais tshuaj khomob;
3. Kev haus luam yeeb;
4. Coenzyme Q10 yog suav tias muaj kev nyab xeeb rau kev siv thaum cev xeeb tub. Txawm li cas los xij, yog tias koj cev xeeb tub, tsis txhob siv cov khoom no yam tsis muaj lus qhia kho mob.
5. Nws tsis paub tias nws yuav nkag mus rau hauv cov kua mis los yog nws yuav ua rau muaj mob rau tus menyuam mos.
Tsis txhob siv cov khoom no yam tsis muaj kws kho mob cov lus qhia yog tias koj pub niam mis rau menyuam.
Q10 npaum li cas koj yuav tsum noj ib hnub
1. Cov tshuaj rau cov neeg laus: noj 10-15mg qhov ncauj ib zaug, peb zaug hauv ib hnub, tom qab noj mov.
2. Cov tshuaj me nyuam: noj 10-20mg qhov ncauj ib zaug, 2-3 zaug ib hnub. Nws yuav tsum tau ua raws li kev saib xyuas ntawm tus neeg laus thiab tus kws kho mob.
Yuav Ua Li Cas Ntsuas Coenzyme Q10
1. Chromatographic tej yam kev mob thiab system haum xeem: Octadecylsilane bonded silica gel yog siv los ua muab tub lim; methanol-absolute ethanol (1: 1) yog siv los ua lub sijhawm txawb; sab kub yog 35 degree; nrhiav wavelength yog 275nm. Noj cov khoom tsim nyog ntawm coenzyme Q10 siv cov khoom siv thiab coenzyme Q9 cov khoom siv, yaj thiab dilute nrog cov ethanol kiag li los ua cov tshuaj sib xyaw uas muaj txog 0.2mg hauv txhua 1ml, noj 20ul thiab txhaj rau hauv cov kua chromatograph, ncov ntawm coenzyme Q9 thiab lub ncov ntawm coenzyme Q10 Qhov kev daws teeb meem yuav tsum muaj ntau dua 6.5, thiab tus naj npawb ntawm cov ntawv theoretical xam raws li lub ncov coenzyme Q10 yuav tsum tsis pub tsawg dua 3000.
2.Txoj kev txiav txim siab: Noj 20mg ntawm cov khoom no, ntsuas nws kom raug, ntxiv txog 40mL ntawm ethanol kiag li, co thiab yaj hauv 50 degree dej da dej. Cia txias, hloov mus rau 100mL ntsuas lub raj mis, dilute mus rau lub cim nrog kiag li ethanol, co zoo raws li cov tshuaj ntsuam xyuas, ntsuas kom raug 20 μL, txhaj rau hauv cov kua chromatograph, thiab sau cov chromatogram; noj lwm qhov tsim nyog ntawm coenzyme Q10 cov khoom siv, thiab ntsuas nws nrog tib txoj kev. Raws li tus txheej txheem sab nraud los xam cov cheeb tsam ncov, uas yog.
Yuav ntim thiab khaws Q10 li cas?
Ntim: export qib ntim nruas, lub tshuab nqus tsev ntim aluminium foil ntim, kuj tuaj yeem ntim raws li cov neeg siv khoom xav tau.
Cia: thov khaws cia rau hauv qhov chaw txias thiab qhuav kom tsis txhob muaj lub teeb ci thiab kub.
Yog tias koj xav yuav Q10, thov hu rau Xi'an Sonwu.
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