Cov ntshav qab zib siab, lossis hyperglycemia, feem ntau suav hais tias yog teeb meem metabolic nkaus xwb. Txawm li cas los xij, nws cov teebmeem yog kev ua haujlwm, txuas mus deb dhau ntawm qhov dej - paub txog cov teeb meem cuam tshuam rau lub qhov muag, lub raum, thiab lub paj hlwb. Ib qho chaw tseem ceeb thiab feem ntau saib tsis taus yog kab mob plab, qhov uas tswj ntshav qab zib tsis zoo tuaj yeem ua rau muaj ntau yam teeb meem kev noj qab haus huv. Kev nkag siab txog kev sib txuas ntawm cov ntshav siab thiab ntshav qab zib yog qhov tseem ceeb, vim tias cov teeb meem hauv plab hnyuv tuaj yeem ua rau muaj kev tswj hwm ntshav qab zib ntau ntxiv thiab txo qis lub neej zoo.
Yog li, cov ntshav qab zib siab puas ua rau muaj teeb meem hauv plab hnyuv?
Dab tsi yog qee yam ntshav qab zib- cuam tshuam txog kev mob plab hnyuv?
Mob ntshav qab zib autonomic neuropathy, lossis cov hlab ntsha puas tsuaj cuam tshuam rau lub paj hlwb tsis muaj zog (xws li lub plab zom mov), yog qhov ua rau muaj ntau yam mob ntshav qab zib tseem ceeb - cuam tshuam txog plab hnyuv:
1. Gastroparesis (Nyob rau hauv lub plab zom mov)
Qhov no yog qhov sib cav ntau tshaj plaws thiab mob plab hnyuv loj cuam tshuam nrog ntshav qab zib. Kev puas tsuaj rau cov hlab ntsha vagus (uas tswj cov leeg nqaij ntawm lub plab) tuaj yeem ua rau qeeb lossis ua kom tiav ntawm plab hnyuv.
Cov tsos mob muaj xws li thaum ntxov satiety (xav tias tag nrho tom qab noj tsuas yog me me ntawm cov zaub mov), postprandial fullness, tsam plab, xeev siab, ntuav ntawm undigested zaub mov, thiab mob plab mog. Lub voj voog vicious, feem ntau tshwm sim los ntawm gastroparesis, ua rau cov ntshav qab zib tswj tau nyuaj heev vim tias ncua sij hawm thiab kev nqus zaub mov tsis tuaj yeem ua rau muaj kev hloov pauv loj hauv cov ntshav qab zib.
2. Enteropathy (Gut Problems)
Qhov no yog hais txog cov teeb meem cuam tshuam rau cov hnyuv me thiab cov hnyuv loj, ua rau qee qhov tshwm sim tab sis thab cov tsos mob:
Mob ntshav qab zib raws plab: tuaj yeem mob ntev, noj hmo, lossis tsis sib xws, feem ntau yog vim muaj kev hloov pauv hauv plab hnyuv, cov kab mob hauv plab me me (SIBO), lossis txo cov kua dej thiab kev nqus.
Slowed colonic motility yog ib qho tsos mob ntawm cem quav, uas tuaj yeem ua rau cem quav ntev.
Kev tswj lub plab qeeb vim cov hlab ntsha puas tsuaj rau lub qhov quav sphincter tuaj yeem ua rau muaj teeb meem hauv kev tswj cov quav.
3. Esophageal Involvement thiab Reflux
Cov ntshav qab zib siab tuaj yeem ua rau txoj hlab pas ua haujlwm tsis zoo, ua rau muaj kab mob gastroesophageal reflux (GERD), uas feem ntau tshwm sim los ntawm kev ua kom tsis zoo ntawm cov hlab pas qis, ua rau lub plab acid rov qab mus rau hauv txoj hlab pas thiab ua rau kub siab thiab, qee zaum, nqos nyuaj (dysphagia).
4. Nonalcoholic Fatty Liver Disease (NAFLD)
Thaum NAFLD tsis yog ib qho teeb meem ntawm plab hnyuv siab raum, nws yog ib qho teeb meem ntawm hom 2 mob ntshav qab zib mellitus thiab insulin tsis kam, uas tshwm sim los ntawm cov rog ntau dhau hauv daim siab hlwb. Cov kab mob no tuaj yeem txhim kho mus rau hauv cov kab mob uas tsis yog-coholic steatohepatitis (NASH), uas cuam tshuam nrog kev mob thiab daim siab puas.
Yog li, teeb meem kev noj qab haus huv dab tsi tuaj yeem tswj cov ntshav qab zib tsis zoo tuaj yeem ua rau?
Kev puas tsuaj los ntawm kev tswj cov ntshav qab zib tsis zoo (hloov hyperglycemia) yog qhov sib ntxiv, cuam tshuam rau lub cev cov hlab ntsha thiab cov hlab ntsha, ua rau muaj kev cuam tshuam loj rau ntev -, feem ntau muab faib ua kab mob macrovascular (cov kab mob tseem ceeb ntawm cov hlab ntsha) thiab kab mob microvascular (mob hlab ntsha me).
1. Cov teeb meem Macrovascular: Cov ntshav qab zib siab ua rau cov hlab ntsha thiab cov hlab ntsha nqaim (atherosclerosis), ua rau muaj kev pheej hmoo ntawm plawv nres thiab mob stroke. Thaum cov hlab ntsha peripheral (PADs) raug mob, cov ntshav ntws txo qis, tshwj xeeb tshaj yog rau ob txhais ceg thiab ko taw, ua rau mob thiab rwj.
2. Microvascular Complications: Mob ntshav qab zib nephropathy (mob raum): ntshav qab zib siab ua rau lub nra ntawm lub raum pom, thaum kawg ua rau lub raum tsis ua haujlwm, thiab mob hnyav, txawm tias yuav tsum tau lim ntshav lossis hloov lub raum. Mob ntshav qab zib retinopathy (mob qhov muag): Kev puas tsuaj rau cov hlab ntsha me me hauv retina tuaj yeem ua rau muaj teeb meem tsis pom kev, nrog rau qhov muag tsis pom. Mob ntshav qab zib neuropathy ( paj hlwb puas ) cuam tshuam cov hlab ntsha thoob plaws hauv lub cev, ua rau mob, tingling, thiab loog (feem ntau ntawm tes thiab ko taw), nrog rau kev ua haujlwm tsis zoo ntawm cov hnyuv (raws li tau piav qhia saum toj no) thiab ntawm cov zis thiab cov kab mob hauv lub cev.
Cov teeb meem plab hnyuv dab tsi tuaj yeem ua rau poob phaus?
Kev poob phaus tsis tuaj yeem ua rau nws tus kheej yog ib qho cim ntawm cov ntshav qab zib siab. Txawm li cas los xij, cov teeb meem hauv plab hnyuv tuaj yeem ua rau poob phaus, feem ntau vim yog cov khoom noj tsis txaus lossis txo qis qab los noj mov. Kab mob plab hnyuv loj (IBD, suav nrog Crohn's disease thiab ulcerative colitis) tuaj yeem ua rau mob plab hnyuv. Qhov mob no tuaj yeem ua rau malabsorption, raws plab, nce calorie ntau ntau, thiab txo qis qab los noj mov vim mob plab thiab xeev siab.
Kab mob Celiac yog ib hom kab mob autoimmune uas noj gluten ua rau cov kab mob hauv cov hnyuv, ua rau mob plab tsis zoo, mob plab, tsam plab, thiab poob phaus tom qab. Tib lub sijhawm, cov kab mob peptic tuaj yeem ua rau qhib qhov txhab hauv plab lossis cov hnyuv loj. Qhov mob los ntawm qhov txhab, tshwj xeeb tshaj yog tom qab noj mov, tuaj yeem ua rau tsis qab los noj mov thiab ntuav, ua rau poob phaus. Gastroparesis (feem ntau hauv cov ntshav qab zib) tuaj yeem ua rau mob plab, xeev siab, thiab ntuav, uas txwv tsis pub noj zaub mov hnyav, ua rau tsis muaj zaub mov noj thiab poob phaus.
Yog li ntawd, hais txog cov xwm txheej nyuaj uas tshwm sim los ntawm cov ntshav qab zib siab yuav tsum tau ua haujlwm ntev, nyuaj. Kev nce qib tsis ntev los no hauv kev lag luam kws tshuaj tau ua rau muaj ntau yam kev kho mob, xws li rettrutide. Cov peptide no-zoo li cov khoom siv tau txais kev saib xyuas tseem ceeb hauv kev noj qab haus huv metabolic vim nws ntau - lub hom phiaj ntawm kev ua haujlwm. Tsis zoo li ib txwm ib txwm muaj - cov khoom siv receptor, cov khoom siv no nthuav tawm cov txiaj ntsig zoo thoob plaws ntau qhov ntev, suav nrog kev tswj ntshav qab zib, tswj qhov hnyav, thiab lub plab ua haujlwm.