J147 hmoov

Taw qhia

J147 hmoovyog ib qho curcumin thiab Cyclohexyl-Bisphenol A (CBA) derivative uas yog cov tshuaj muaj zog neurogenic thiab neuroprotective. Nws tau tsim los rau kev siv kho cov mob neurodegenerative cuam tshuam nrog kev laus. Curcumin yog ib qho polyphenol thiab lub luag haujlwm tseem ceeb ntawm turmeric thiab Ginger thiab muaj ntau cov txiaj ntsig pov thawj hauv kev kho mob ntau yam, tab sis vim nws tsis muaj peev xwm hla cov ntshav-hlwb barrier (BBB), muaj cov kev txwv tseeb. Txawm li cas los xij, J147 tuaj yeem hla cov ntshav-hlwb thaiv mus rau hauv lub hlwb (muaj zog) thiab ua rau cov kab mob neuronal qia cell tsim. Xi'an Sonwu, ua cov chaw tsim khoom thiab cov muag khoom hauv Suav teb, tuaj yeem muab cov khoom lag luam zoo nrog tus nqi txaus nyiam. Yog tias koj xav tau J147, thov hu rau Xi'an Sonwu.

Specification

Muaj nuj nqi

1. Txhim kho mitochondria kev ua haujlwm thiab kev ua haujlwm ntev

J147 ua haujlwm los ntawm kev khi rau hauv mitochondria, cov hlwb uas muaj lub luag haujlwm tsim lub zog hauv peb lub cev. Qhov kev txiav txim ntawm J147 pab tiv thaiv oxidative kev nyuaj siab nyob rau hauv mitochondria hlwb, ua rau lub cell ua hauj lwm zoo dua thiab ntev. J147 zoo heev los tiv thaiv oxidative kev nyuaj siab thiab txhim kho mitochondrial muaj nuj nqi.

Piv txwv li, J147 nce mitochondrial muaj nuj nqi los ntawm kev txhim kho ATP qib (inhibiting ATP synthase, tshwj xeeb ATP5A). Los ntawm inhibiting ATP synthase, J147 tuaj yeem txo cov tshuaj lom metabolites uas ua rau excitotoxicity, cov txheej txheem los ntawm cov hlwb tuag los ntawm kev zoo siab heev. Qhov no tso cai rau kev noj qab haus huv ntau dua / hluas mitochondria (ntawm qib molecular los ntawm kev hloov kho AMPK / mTOR txoj hauv kev).

2. Tiv thaiv Alzheimer's Disease

Raws li cov kev sim uas cuam tshuam, J147 thim rov qab kev paub tsis meej hauv tus qauv nas ntawm Alzheimer's Disease. J147 tuaj yeem txhim kho Amyloid-Beta (A) metabolism thiab txo cov qib hauv lub hlwb los ntawm kev txo cov protein ntau ntawm -Secretase (BACE). Hauv cov qauv tsiaj ntawm AD, J147 tuaj yeem tiv thaiv BBB permeability homeostasis thiab txhim kho cov hlab ntsha hauv lub hlwb. Nws kuj tseem tuaj yeem nce qib ntawm Docosahexaenoic Acid (DHA) hauv lub hlwb. J147 tuaj yeem kho cov qib Glutamate (synthesized los ntawm TCA intermediate -ketoglutarate) hauv hlwb. Dhau li ntawd, J-147 curcumin modulates neurotrophin signaling los lav neuronal ciaj sia taus, li no, nco tsim thiab cognition.

Cov neeg mob nrog AD muaj tsawg dua cov teeb meem neurotrophic. Txawm li cas los xij, kev noj J-147 Alzheimer's supplement boosts NGF thiab BDNF. Cov neurotransmitters no pab tsim kev nco, kev kawm, thiab kev txawj ntse.

3. Txhim kho kev nco

J147 kuj tau qhia ntau qhov kev cog lus ntawm cov qauv nas ntsuas hauv kev txhim kho kev nco. Nws txhim kho kev nco hauv cov nas nrog AD thiab cov qauv qub qub. Txawm hais tias hauv cov qauv tsiaj qub heev, J147 tuaj yeem thim rov qab qhov kev paub tsis txaus ntseeg loj heev.Cov tshuaj txawm tau pab rov qab qhov kev xav tsis zoo hauv cov kev xeem laus thaum cov kev tshawb fawb tshawb fawb. J147 kuj tseem tuaj yeem txhim kho qhov chaw nco thiab txhim kho Long-Term Potentiation (LTP).

4. Tiv thaiv neurons thiab pab lub hlwb loj hlob

J147 kuj muaj cov khoom tiv thaiv neuroprotective uas tiv thaiv oxidative kev ua hauv hlwb. Qhov no pab tiv thaiv neurons los ntawm kev puas tsuaj. J147 tuaj yeem ua rau lub hlwb loj hlob. Nws kuj tseem tuaj yeem txhim kho synaptic plasticity hauv lub hlwb, ua rau kev loj hlob. Nws tuaj yeem tiv thaiv kev tuag neuronal uas yog vim oxidative kev nyuaj siab. Cov tshuaj ntxiv no tseem thaiv cov kev ua haujlwm dhau ntawm NMDA (N-Methyl-D-aspartate) receptors, uas yog lub luag haujlwm rau neurodegeneration. Noj J-147 tshuaj yuav txhawb nqa lub hlwb-derived neurotrophic yam (BDNF) thiab cov paj hlwb loj hlob (NGF). Ob lub neurotransmitters no ua rau cov kab mob neurodegenerative xws li Alzheimer's thiab dementia. Dab tsi ntxiv, BDNF tseem ceeb hauv neurogenesis.

Txoj cai ua haujlwm

J147 hmoovs cov nyhuv ntawm lub cell tseem tsis paub txog kom txog thaum Salk lub koom haum Neurobiologists txiav txim siab qhov puzzle. Cov tshuaj ua haujlwm los ntawm kev khi rau ATP synthase. ATP synthase, tseem hu ua Adenosine Triphosphate Synthase, yog mitochondrial protein uas ua haujlwm los pab cov hlwb tsim ATP. ATP yog mitochondrial cell lub zog txiaj. Qhov no mitochondrial protein modulates zus tau tej cov cellular zog, li no, tswj txoj kev laus.

Raws li cov kws tshawb fawb, qhov muaj J-147 ntxiv rau hauv tib neeg lub cev tiv thaiv kev muaj hnub nyoog txog cov tshuaj lom uas tshwm sim los ntawm kev ua haujlwm tsis zoo ntawm mitochondria thiab overproduction ntawm ATP. Nws kuj tseem pom tias J147 ua rau txhim kho kev tsim khoom ntawm ATP hauv lub cev. Cov tshuaj kuj tseem tuaj yeem pab tswj cov mitochondria, uas yog qhov tseem ceeb hauv kev tiv thaiv kev laus. Qhov tseem ceeb ntawm cov kev ua no tseem ceeb rau ib qho laj thawj. Qhov no yog vim qhov loj tshaj plaws ua rau Alzheimer's, dementia, thiab lwm yam kev txawj ntse yog kev laus. Nrhiav txoj hauv kev kom qeeb lossis thim rov qab cov teebmeem ntawm kev laus hauv lub hlwb tuaj yeem muaj txiaj ntsig zoo hauv kev kho Alzheimer's.

J147 kuj tau siv los tsom rau kev tsim cov protein beta-amyloid. Kev sib sau siab ntawm cov protein no hauv cov neeg mob Alzheimer tau tshaj tawm hauv kev tshawb fawb yav dhau los. J147 aims kom tshem tawm cov beta-amyloid plaque tsub zuj zuj, uas nyob rau hauv lem yuav pab tau rov qab los yog tiv thaiv kev loj hlob ntawm Alzheimer's thiab lwm yam teeb meem kev txawj ntse.

Factory & Certifications

Shipping & Ntim

Peb Qhov Zoo

1. Xi'an Sonwu tau koom nrog ntshuam-export rau ntau tshaj 10 xyoo nrog kev nplua nuj nyob rau hauv txoj kev loj hlob, kev tshawb fawb thiab zus tau tej cov API, cog extract, zaub mov additives, thiab lwm yam raw cov khoom xyaw ntawm cov khoom kho mob.

2. Xi'an Sonwu muaj cov kws tshaj lij nrog kev faib ua haujlwm kom meej.

3. Cov khoom raug kuaj los ntawm cov neeg thib peb.

4. Kev pabcuam OEM muaj.

Xi'an Sonwu tuaj yeem muab cov khoom zoo J147 nrog tus nqi tsim nyog. Yog xav yuavJ147 hmoov, txais tos hu rau Xi'an Sonwu.

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