Vinblastine Sulfate hmoov

Dab tsi yog Ntuj Qhov Chaw Ntawm Vinblastine
Vinblastine sulfate hmoov, tseem hu ua vincristine, yog alkaloid rho tawm los ntawm cov nroj tsuag Catharanthus roseus. Vincristine yog bisindole-hom alkaloid. Nws cov txiaj ntsig kho mob yog kwv yees li kaum npaug siab dua li ntawm vinblastine. Nws tuaj yeem siv los kho tus mob lymphoblastic leukemia nrog kev ua tau zoo. Nws kuj zoo kho lwm yam mob leukemias, Hodgkin's kab mob, thiab lymphosarcoma. Nws tseem muaj txiaj ntsig zoo hauv reticulum cell sarcoma thiab kab mob ntawm lub mis. Cov alkaloids muaj nyob rau hauv Vinca loj, ua ke nrog vinblastine, pangolin, thiab pefloxacin, muaj cov nyhuv ntawm kev txwv kev faib cell (mitosis) hauv metaphase. Qhov ntawd zoo ib yam li colchicine, tab sis nws qhov cuam tshuam muaj zog dua colchicine. Zoo li colchicine, nws tuaj yeem khi rau tubulin thiab inhibit nws txoj haujlwm lom neeg, tab sis qhov chaw sib txawv. Tsis tas li ntawd, tsis zoo li colchicine, nws kuj ua rau cov proteins uas tsis yog tubulin, xws li actin thiab 10-nanometer filament protein.
Nws yog siv nyob rau hauv kev kho mob tshuaj raws li ib tug ntawm cov anti-lesion cell pab pawg neeg, tshwj xeeb tshaj yog zoo tiv thaiv kab mob ntawm hematopoietic kab mob. Vinblastine sulfate tuaj yeem siv los kho Hodgkin tus kab mob thiab chorioepithelial carcinoma nrog kev ua tau zoo; Nws kuj tseem siv tau rau kev kho mob lymphosarcoma, reticulocyte sarcoma, mob leukemia (VP, "V" hauv VDLP program vincristine, thiab D yog Daunorubicin ("L" sawv cev rau asparaginase, "P" sawv cev rau prednisone), kab mob ntawm lub mis, nephroblastoma, Cov kab mob ntawm zes qe menyuam, kab mob qog ntshav, neuroblastoma, thiab malignant melanoma kuj muaj cov teebmeem tshwj xeeb.Yog tias koj tseem xav siv tshuaj khomob, thov hu rau Xi'an Sonwu. Xi'an Sonwu tuaj yeem muab cov tshuaj dawb huv vincristine sulfate rau koj.

Certificate Of Analysis

Vinblastine Sulfate yuav online
Xi'an Sonwu Biotech Co. Ltd. muaj ntau tshaj kaum xyoo ntawm kev lag luam kev lag luam, tshwj xeeb hauv kev tsim thiab muag cov ntaub ntawv raw. Xi'an Sonwu tau tsim kev sib koom tes ruaj khov thiab txhim khu kev qha nrog cov teb chaws hauv Asmeskas, Asia, Europe, thiab Oceania. Xi'an Sonwu muab cov khoom zoo ua ntej thiab siv zog los muab txhua tus neeg siv khoom nrog cov kev pabcuam zoo kom tau raws li lawv cov kev xav tau tag nrho.
Xi'an Sonwu muab qhov tseem ceeb rau cov khoom lag luam zoo, thiab nws txoj kev cog lus rau kev ua tau zoo yog pom tseeb hauv txhua yam, suav nrog kev xaiv cov khoom siv, kev tsim khoom, kev sim qauv, thiab kev tshaj lij ntawm nws cov neeg ua haujlwm. Los ntawm kev tswj hwm txhua qhov kev nthuav dav, Xi'an Sonwu tuaj yeem txo tus nqi yam tsis muaj kev cuam tshuam zoo, ua kom cov neeg siv khoom tau txais cov khoom muaj txiaj ntsig tshwj xeeb.
Xi'an Sonwu zoo siab rau cov lus pom zoo uas nws tau txais los ntawm cov neeg siv khoom, uas tau lees paub qhov zoo ntawm cov khoom. Txhawm rau ua pov thawj ntxiv cov khoom lag luam, Xi'an Sonwu yuav muab 99 vinblastine sulfate cov qauv rau koj kuaj.

Cov neeg siv khoom zoo lus

Dab tsi yog Vincristine Sulphate siv rau
Vinblastine sulfate hmoovyog siv los kho ntau yam mob hnyav, suav nrog:
1. Leukemia
Leukemia yog ib hom kab mob uas muaj qhov txawv txav ntawm cov qe ntshav dawb. Qee zaum, cov qe ntshav dawb no txawv txav thiab tsis tuaj yeem ua haujlwm li qub. Leukemia tuaj yeem muab faib ua ob hom: mob lymphoblastic leukemia thiab mob myeloid leukemia, raws li hom kab mob thiab kab mob ntev. Vincristine sulfate feem ntau yog siv rau hauv cov tshuaj tua kab mob rau ntau hom leukemia thiab lwm yam kab mob malignant. Nws belongs rau ib chav kawm ntawm cov tshuaj hu ua vincristines (vinca alkaloids), uas thaiv kev loj hlob ntawm cov hlwb tsis zoo. Cov tshuaj no feem ntau yog siv nrog lwm cov tshuaj, suav nrog doxorubicin thiab cyclophosphamide, los tsim ib txoj kev npaj kho mob leukemia ntau dua.

2. Hodgkin tus kab mob
Hodgkin tus kab mob, tseem hu ua lymphomatous kab mob, yog ib tug malignant kab mob ntawm lymphoid cov ntaub so ntswg, feem ntau yog txuam nrog cov qog thiab lymphatic system. Hodgkin tus kab mob tuaj yeem muab faib ua ob hom: classic Hodgkin's kab mob thiab tsis yog-classic Hodgkin's kab mob, nrog rau cov kab mob classic Hodgkin yog feem ntau. Tus kab mob no feem ntau tshwm sim los ntawm kev mob lymphadenopathy, kub taub hau, poob phaus, thiab qaug zog. Kev kho mob ntawm Hodgkin tus kab mob feem ntau suav nrog kev siv tshuaj khomob, xov tooj cua, thiab kev tiv thaiv kab mob. Nyob rau hauv xyoo tas los no, txoj kev kho tshiab xws li kev siv tshuaj tiv thaiv kab mob thiab cov phiaj xwm kho mob kuj tau siv dav los kho Hodgkin tus kab mob. Lub mechanism ntawm kev txiav txim ntawm Vincristine sulfate yog los thaiv mitosis ntawm cov kab mob hlwb, yog li inhibiting lawv txoj kev loj hlob. Feem ntau, nws tau ua ke nrog lwm cov tshuaj chemotherapy los tsim ib txoj kev kho mob ntau dua.

3. Lymphoma
Lymphoma yog ib hom kab mob malignant uas cuam tshuam nrog lymphatic system. Cov kab mob lymphatic suav nrog cov qog nqaij hlav, cov hlab ntsha lymphatic, spleen, tonsils, thiab cov pob txha pob txha. Muaj ntau hom qog ntshav qog ntshav, ntau yam xws li Hodgkin's disease thiab non-Hodgkin's lymphoma, uas yog los ntawm ntau hom lymphocytes. Cov tsos mob ntawm lymphoma tej zaum yuav muaj xws li mob qog nqaij hlav o, ua npaws, poob phaus, tawm hws hmo ntuj, thiab qaug zog.

4. Kab mob hlwb
Cov kab mob hauv lub paj hlwb tshwm sim hauv cov ntaub so ntswg thiab tuaj yeem ua benign lossis malignant. Cov kab mob hauv hlwb yuav ua rau muaj ntau yam tsos mob ntsig txog qhov chaw thiab qhov loj ntawm qhov txhab, nrog rau mob taub hau, xeev siab, ntuav, thiab hnov ​​​​mob lossis lub cev muaj zog. Qee zaum, nws yog siv los kho qee yam mob hlwb, tshwj xeeb tshaj yog nyob rau hauv cov neeg mob me. Vincristine-based chemotherapy tshuaj inhibit kev loj hlob thiab kis los ntawm kev thaiv cov kab mob mitosis hauv cov kab mob. Kev kho mob ntawm cov kab mob hauv lub hlwb feem ntau yog kev kho mob ntau yam, suav nrog kev phais phais, xov tooj cua, tshuaj kho mob, kev kho mob, thiab kev txhawb nqa cov tsos mob. Kev phais phais feem ntau yog ib qho ntawm thawj txoj kev kho mob, thiab Vincristine sulfate yuav siv tau los ua kev kho mob ntxiv los tswj lossis txo qhov kev loj hlob ntawm qhov txhab.

5. Lwm yam kab mob
Vincristine sulfate tuaj yeem kho lwm yam kab mob, xws li neuroblastoma, rhabdomyosarcoma, nephroblastoma, thiab lwm yam.

Dab tsi yog Mechanism Ntawm Kev Ua Ntawm Vinblastine Sulphate
Vinblastine sulfate inhibits cell division thiab cell voj voog ntes los ntawm kev tiv thaiv kev tsim cov microtubules, uas cuam tshuam mitotic spindle sib dhos thiab muaj cov nyhuv kho. Nws yog ib qho mitosis inhibitor uas khi rau -tubulin, microtubule protein tivthaiv, ua rau microtubule depolymerization thiab cuam tshuam qhov sib npaug ntawm qhov sib npaug ntawm cov microtubule sib dhos. Kev cuam tshuam nrog cov theem metaphase ntawm cell faib los ntawm qhov cuam tshuam ntawm microtubule dynamics thaum kawg ua rau cell tuag. Nws tuaj yeem cuam tshuam rau cov cell membrane, tiv thaiv kev tsim cov proteins thiab RNA thiab cuam tshuam nrog kev hloov pauv ntawm cov amino acids. Vinblastine zoo tiv thaiv ntau yam kab mob txaus ntshai. Nws pom tau tias muaj zog tiv thaiv nas L1210 leukemia, Ehrlich ascites mob, S180, C3H nas tshwm sim thiab kab mob metastatic mis, thiab tseem pab tau rau kev hloov pauv ntawm koob tshuaj 0.05 txog 0.1 mg / kg. Tsis tas li ntawd, nws tiv thaiv kev loj hlob ntawm cov kab mob chorionic hlwb hauv hamster sab plhu pouches.

Dab tsi yog Qhov Kev Mob Phem Ntawm Vincristine Sulfate
Kev phiv tshuaj
1. Hematological toxicity: Nws yog ib qho tshuaj tiv thaiv kab mob. Cov tshuaj tua kab mob hauv pob txha muaj zog dua li vincristine, thiab nws rov zoo sai sai tom qab tso tseg cov tshuaj.
2. Cov kab mob hauv plab: tsis qab los noj mov, xeev siab, ntuav, raws plab, mob plab, stomatitis, thiab lwm yam.
3. Peripheral paj toxicity: loog ntawm cov ntiv tes (ntiv taw) cov lus qhia, mob nyob rau hauv nqua, nqaij ntshiv, poob ntawm tendon reflexes, thiab lwm yam.
4. Lwm tus: Ob peb tus neeg mob yuav ntsib orthostatic hypotension, plaub hau poob, insomnia, mob taub hau, thiab lwm yam.
Kev sib tham
Itraconazole tuaj yeem inhibit hepatic cytochrome P4503A, thiab vincristine metabolized los ntawm hepatic cytochrome P4503A. Kev siv ua ke tuaj yeem cuam tshuam cov metabolism ntawm vincristine thiab ua rau muaj kev phiv ntawm cov khoom no ntawm cov leeg thiab cov hlab ntsha.
Ua ke cov khoom no nrog platinum-muaj cov tshuaj tiv thaiv kab mob malignant tuaj yeem txhim kho qhov thib yim khub ntawm cov hlab ntsha tawg.
Thaum ua ke nrog asparaginase, cov tshuaj no tuaj yeem ua rau cov ntshav siab thiab cov kab mob hauv lub paj hlwb. Thov nco ntsoov, vincristine sulfate tuaj yeem siv tau 12-24 teev ua ntej kev tswj hwm L-asparaginase.
Cov khoom no tuaj yeem tiv thaiv methotrexate los ntawm kev tawm ntawm cov hlwb thiab ua rau kom cov ntshav siab nyob rau tom kawg. Yog li, cov khoom no feem ntau txhaj tshuaj ua ntej, thiab tom qab ntawd siv methotrexate.
Kev siv cov khoom no nrog isoniazid thiab txha caj qaum hluav taws xob tuaj yeem ua rau lub paj hlwb toxicity.
Cov koob tshuaj yuav tsum raug txo kom tsawg yog tias lwm cov tshuaj leukocyte-txo qis nyob rau hauv kev sib xyaw ua ke ntawm cov tshuaj khomob. Hauv cov kab mob siab tsis txaus, koob tshuaj yuav tsum raug txo yog tias lwm cov tshuaj khomob uas tau tso tawm los ntawm cov kua tsib (xws li doxorubicin) tau koom nrog. Thaum ua ke nrog allopurinol, colchicine, lossis probenecid, vinblastine tuaj yeem ua rau cov ntshav uric acid nce ntxiv.

Hoobkas
1. Xi'an Sonwu Biotech Co., Ltd muaj lub Hoobkas tsim, tsim khoom, thiab khaws cov khoom, yog li nws muaj cov khoom tsim nyog. Xi'an Sonwu muaj kev txiav txim kom zoo, huv si, thiab huv si ntau lawm. Nyob rau hauv Xi'an Sonwu, cov kws tshawb fawb tuaj yeem tsim cov khoom tshiab zoo.
2. Xi'an Sonwu muaj cov cai nruj rau cov neeg ua haujlwm faib los ntawm kev tsim khoom thiab kev sim rau kev muag khoom. Tag nrho cov khoom escorting yog lav los ntawm uncompromising cov ntaub ntawv txhawb nqa thiab kev pab cuam tom qab muag.

Daim ntawv pov thawj

Pob

Logistics

Dhau li lav cov khoom, lwm qhov tseem ceeb tshaj plaws yog cov neeg siv khoom tuaj yeem tau txais cov khoom zoo. Yog li, Xi'an Sonwu muab txhua yam kev xa khoom raws li kev xav tau sib txawv.

FAQ
Qhov ntau npaum li cas rau cov neeg laus yog 1 ~ 2 mg (los yog 1.4 mg / m2) thiab tsis ntau tshaj 2 mg. Qhov ntau npaum li cas rau cov neeg laus dua 65 yog 1 mg txhua lub sijhawm. Cov menyuam yaus: 75 ug/kg lossis 2.0 mg/m2, txhaj tshuaj rau hauv cov hlab ntsha lossis infusion ib zaug ib lub lim tiam. Kev sib xyaw tshuaj khomob yog siv tsis tu ncua rau ob lub lis piam ua lub voj voog.
Yog tias koj xav paub txog 99 vinblastine sulfate chaw tsim tshuaj paus, koj tuaj yeem tiv tauj Xi'an Sonwu. Nyem rau email, thiab tom qab ntawd koj tau txais cov khoom zoovinblastine sulfate hmoov.
Email:sales@sonwu.com

Cim npe nrov: vinblastine sulfate hmoov, Tuam Tshoj, lwm tus neeg, manufacturers, hoobkas, lag luam wholesale, yuav, nqe, tej, ntshiab, raw, mov, kev muag khoom